Cadherin-mediated cellular signaling

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Noren, 2000, p120 catenin regulates the actin cytoskeleton via Rho family GTPases, J Cell Biol, 150, 567, 10.1083/jcb.150.3.567

Grosheva, 2001, p120 catenin affects cell motility via modulation of activity of Rho-family GTPases: a link between cell–cell contact formation and regulation of cell locomotion, J Cell Sci, 114, 695, 10.1242/jcs.114.4.695

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Goodwin M, Kovacs EM, Thoreson MA, Reynolds AB, Yap AS: Minimal mutation of the cytoplasmic tail inhibits the ability of E-cadherin to activate rac but not PI3-kinase. Direct evidence of a role for cadherin-activated Rac signaling in adhesion and contact formation. J Biol Chem 2003, in press.

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George-Weinstein, 1997, N-cadherin promotes the commitment and differentiation of skeletal muscle precursor cells, Dev Biol, 185, 14, 10.1006/dbio.1997.8542

Meriane, 2000, Critical activities of Rac1 and Cdc42Hs in skeletal myogenesis: antagonistic effects of JNK and p38 pathways, Mol Biol Cell, 11, 2513, 10.1091/mbc.11.8.2513

Carnac, 1998, RhoA GTPase and serum response factor control selectively the expression of MyoD without affecting Myf5 in mouse myoblasts, Mol Biol Cell, 9, 1891, 10.1091/mbc.9.7.1891

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Lambert, 2002, Dynamics of ligand-induced, Rac1-dependent anchoring of cadherins to the actin cytoskeleton, J Cell Biol, 157, 469, 10.1083/jcb.200107104

Lampugnani, 2002, VE-cadherin regulates endothelial actin activating Rac and increasing membrane association of Tiam, Mol Biol Cell, 13, 1175, 10.1091/mbc.01-07-0368

Kouklis P, Konstantoulaki M, Malik AB: VE-cadherin induced Cdc42 signaling regulates formation of membrane protrusions in endothelial cells. J Biol Chem 2003, in press.

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Simcha, 2001, Cadherin sequences that inhibit β-catenin signaling: a study in yeast and mammalian cells, Mol Biol Cell, 12, 1177, 10.1091/mbc.12.4.1177

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Stockinger, 2001, E-cadherin regulates cell growth by modulating proliferation-dependent β-catenin transcriptional activity, J Cell Biol, 154, 1185, 10.1083/jcb.200104036

van de Wetering, 2001, Mutant E-cadherin breast cancer cells do not display constitutive Wnt signaling, Cancer Res, 61, 278

Gottardi, 2001, E-cadherin suppresses cellular transformation by inhibiting β-catenin signaling in an adhesion-independent manner, J Cell Biol, 153, 1049, 10.1083/jcb.153.5.1049

Doherty, 2000, CAMs and axonal growth: a critical evaluation of the role of calcium and the MAPK cascade, Mol Cell Neurosci, 16, 283, 10.1006/mcne.2000.0907

Skaper, 2001, Cell signalling cascades regulating neuronal growth-promoting and inhibitory cues, Prog Neurobiol, 65, 593, 10.1016/S0301-0082(01)00017-X

Utton, 2001, Soluble N-cadherin stimulates fibroblast growth factor receptor dependent neurite outgrowth and N-cadherin and the fibroblast growth factor receptor co-cluster in cells, J Neurochem, 76, 1421, 10.1046/j.1471-4159.2001.00140.x

Williams, 2002, Dimeric versions of two short N-cadherin binding motifs (HAVDI and INPISG) function as N-cadherin agonists, J Biol Chem, 277, 4361, 10.1074/jbc.M109185200

Kim, 2000, N-cadherin extracellular repeat 4 mediates epithelial-to-mesenchymal transition and increased motility, J Cell Biol, 151, 1193, 10.1083/jcb.151.6.1193

Nieman, 1999, N-cadherin promotes motility in human breast cancer cells regardless of their E-cadherin expression, J Cell Biol, 147, 631, 10.1083/jcb.147.3.631

Hazan, 2000, Exogenous expression of N-cadherin in breast cancer cells induces cell migration, invasion, and metastasis, J Cell Biol, 148, 779, 10.1083/jcb.148.4.779

Wheelock, 2001, Cadherin junctions in mammary tumors, J Mammary Gland Biol Neoplasia, 6, 275, 10.1023/A:1011319507155

Suyama, 2002, A signaling pathway leading to metastasis is controlled by N-cadherin and the FGF receptor, Cancer Cell, 2, 301, 10.1016/S1535-6108(02)00150-2

Carmeliet, 1999, Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis, Cell, 98, 147, 10.1016/S0092-8674(00)81010-7

Zanetti, 2002, Vascular endothelial growth factor induces SHC association with vascular endothelial cadherin: a potential feedback mechanism to control vascular endothelial growth factor receptor 2 signaling, Arterioscler Thromb Vasc Biol, 22, 617, 10.1161/01.ATV.0000012268.84961.AD

Shay-Salit, 2002, VEGF receptor 2 and the adherens junction as a mechanical transducer in vascular endothelial cells, Proc Natl Acad Sci USA, 99, 9462, 10.1073/pnas.142224299

Nakagawa, 2001, Recruitment and activation of Rac1 by the formation of E-cadherin-mediated cell–cell adhesion sites, J Cell Sci, 114, 1829, 10.1242/jcs.114.10.1829

Kuroda, 1998, Role of IQGAP1, a target of the small GTPases Cdc42 and Rac1, in regulation of E-cadherin-mediated cell–cell adhesion, Science, 281, 832, 10.1126/science.281.5378.832

Takaishi, 1997, Regulation of cell–cell adhesion by rac and rho small G proteins in MDCK cells, J Cell Biol, 139, 1047, 10.1083/jcb.139.4.1047

Kuroda, 1999, Cdc42, Rac1, and their effector IQGAP1 as molecular switches for cadherin-mediated cell–cell adhesion, Biochem Biophys Res Commun, 262, 1, 10.1006/bbrc.1999.1122

Noren, 2001, Cadherin engagement regulates Rho family GTPases, J Biol Chem, 276, 33305, 10.1074/jbc.C100306200

Noren NK, Arthur WT, Burridge K: Cadherin engagement inhibits RhoA via p190RhoGAP. J Biol Chem 2003, in press.

Anastasiadis, 2000, Inhibition of RhoA by p120 catenin, Nat Cell Biol, 2, 637, 10.1038/35023588