CaMKII in Vascular Signalling: “Friend or Foe”?

Heart, Lung and Circulation - Tập 27 - Trang 560-567 - 2018
Obialunanma V. Ebenebe1, Alison Heather1, Jeffrey R. Erickson1
1Department of Physiology, School of Medical Sciences and HeartOtago, University of Otago, Dunedin, Otago, New Zealand

Tài liệu tham khảo

Bers, 2009, CaMKII regulation of cardiac ion channels, J Cardiovasc Pharmacol, 54, 180, 10.1097/FJC.0b013e3181a25078 Erickson, 2008, CaMKII and its role in cardiac arrhythmia, J Cardiovasc Electrophysiol, 19, 1332, 10.1111/j.1540-8167.2008.01295.x Erickson, 2013, Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation, Nature, 502, 372, 10.1038/nature12537 Erickson, 2008, A dynamic pathway for calcium-independent activation of CaMKII by methionine oxidation, Cell, 133, 462, 10.1016/j.cell.2008.02.048 Coultrap, 2014, Nitric oxide induces Ca2+-independent activity of the Ca2+/calmodulin-dependent protein kinase II (CaMKII), J Biol Chem, 289, 19458, 10.1074/jbc.M114.558254 Erickson, 2015, S-Nitrosylation induces both autonomous activation and inhibition of calcium/calmodulin-dependent protein kinase II delta, J Biol Chem, 290, 25646, 10.1074/jbc.M115.650234 Tobimatsu, 1989, Tissue-specific expression of four types of rat calmodulin-dependent protein kinase II mRNAs, J Biol Chem, 264, 17907, 10.1016/S0021-9258(19)84658-6 Caran, 2001, Cytosolic targeting domains of gamma and delta calmodulin-dependent protein kinase II, J Biol Chem, 276, 42514, 10.1074/jbc.M103013200 Zhang, 2007, CaMKIIdelta isoforms differentially affect calcium handling but similarly regulate HDAC/MEF2 transcriptional responses, J Biol Chem, 282, 35078, 10.1074/jbc.M707083200 Gray, 2014, CaMKIIdelta subtypes: localization and function, Front Pharmacol, 5, 15, 10.3389/fphar.2014.00015 Vanhoutte, 1989, Endothelium and control of vascular function. State of the Art lecture, Hypertension, 13, 658, 10.1161/01.HYP.13.6.658 Rokolya, 2000, Inhibition of CaM kinase II activation and force maintenance by KN-93 in arterial smooth muscle, Am J Physiol Cell Physiol, 278, C537, 10.1152/ajpcell.2000.278.3.C537 Kim, 2000, Ca2+-calmodulin-dependent protein kinase II-dependent activation of contractility in ferret aorta, J Physiol, 526, 367, 10.1111/j.1469-7793.2000.00367.x Pauly, 1995, Role of calcium/calmodulin-dependent protein kinase II in the regulation of vascular smooth muscle cell migration, Circulation, 91, 1107, 10.1161/01.CIR.91.4.1107 Bilato, 1997, The inhibition of vascular smooth muscle cell migration by peptide and antibody antagonists of the alphavbeta3 integrin complex is reversed by activated calcium/calmodulin- dependent protein kinase II, J Clin Invest, 100, 693, 10.1172/JCI119582 Owens, 2004, Molecular regulation of vascular smooth muscle cell differentiation in development and disease, Physiol Rev, 84, 767, 10.1152/physrev.00041.2003 House, 2007, Calcium/calmodulin-dependent protein kinase II-delta isoform regulation of vascular smooth muscle cell proliferation, Am J Physiol Cell Physiol, 292, C2276, 10.1152/ajpcell.00606.2006 Mercure, 2008, CaM kinase II delta2-dependent regulation of vascular smooth muscle cell polarization and migration, Am J Physiol Cell Physiol, 294, C1465, 10.1152/ajpcell.90638.2007 Striessnig, 2014, L-type Ca(2+) channels in heart and brain, Wiley Interdiscip Rev Membr Transp Signal, 3, 15, 10.1002/wmts.102 Lee, 2006, Calmodulin kinase II is involved in voltage-dependent facilitation of the L-type Cav1.2 calcium channel: identification of the phosphorylation sites, J Biol Chem, 281, 25560, 10.1074/jbc.M508661200 Blaich, 2010, Facilitation of murine cardiac L-type Ca(v)1.2 channel is modulated by calmodulin kinase II-dependent phosphorylation of S1512 and S1570, Proc Natl Acad Sci U S A, 107, 10285, 10.1073/pnas.0914287107 Ross, 1995, Adrenergic control of the force-frequency relation, Circulation, 92, 2327, 10.1161/01.CIR.92.8.2327 Xu, 2010, Alterations of L-type calcium current and cardiac function in CaMKIIδ knockout mice, Circ Res, 107, 398, 10.1161/CIRCRESAHA.110.222562 Bers, 2014, Ca(2+) current facilitation is CaMKII-dependent and has arrhythmogenic consequences, Front Pharmacol, 5, 144, 10.3389/fphar.2014.00144 Gao, 2006, Insulin-like growth factor-1 modulation of CaV1.3 calcium channels depends on Ca2+ release from IP3-sensitive stores and calcium/calmodulin kinase II phosphorylation of the alpha1 subunit EF hand, J Neurosci, 26, 6259, 10.1523/JNEUROSCI.0481-06.2006 Jenkins, 2010, Ca2+-dependent facilitation of Cav1.3 Ca2+ channels by densin and Ca2+/calmodulin-dependent protein kinase II, J Neurosci, 30, 5125, 10.1523/JNEUROSCI.4367-09.2010 Abiria, 2010, CaMKII associates with Ca(V)1.2 L-type calcium channels via selected β subunits to enhance regulatory phosphorylation, J Neurochem, 112, 150, 10.1111/j.1471-4159.2009.06436.x Fleming, 2001, Phosphorylation of Thr495 regulates Ca2+/calmodulin-dependent endothelial nitric oxide synthase activity, Circ Res, 88, e68, 10.1161/hh1101.092677 Hornig, 1997, Endothelial function and bradykinin in humans, Drugs, 54, 42, 10.2165/00003495-199700545-00007 Kobayashi, 2012, Involvement of CaM kinase II in the impairment of endothelial function and eNOS activity in aortas of Type 2 diabetic rats, Clin Sci (Lond), 123, 375, 10.1042/CS20110621 Lipskaia, 2014, Expression of sarco (endo) plasmic reticulum calcium ATPase (SERCA) system in normal mouse cardiovascular tissues, heart failure and atherosclerosis, Biochim Biophys Acta, 1843, 2705, 10.1016/j.bbamcr.2014.08.002 Sutliff, 1999, Phospholamban is present in endothelial cells and modulates endothelium-dependent relaxation. Evidence from phospholamban gene-ablated mice, Circ Res, 84, 360, 10.1161/01.RES.84.3.360 Simmerman, 1986, Sequence analysis of phospholamban. Identification of phosphorylation sites and two major structural domains, J Biol Chem, 261, 13333, 10.1016/S0021-9258(18)69309-3 Napolitano, 1992, Phosphorylation of phospholamban in the intact heart. A study on the physiological role of the Ca(2+)-calmodulin-dependent protein kinase system, J Mol Cell Cardiol, 24, 387, 10.1016/0022-2828(92)93193-N Toyofuku, 1994, Identification of Ser38 as the site in cardiac sarcoplasmic reticulum Ca(2+)-ATPase that is phosphorylated by Ca2+/calmodulin-dependent protein kinase, J Biol Chem, 269, 26492, 10.1016/S0021-9258(18)47221-3 Xu, 1993, Phosphorylation and activation of the Ca(2+)-pumping ATPase of cardiac sarcoplasmic reticulum by Ca2+/calmodulin-dependent protein kinase, J Biol Chem, 268, 8394, 10.1016/S0021-9258(18)52885-4 Grover, 1996, Sarcoplasmic reticulum Ca2+ pump in pig coronary artery smooth muscle is regulated by a novel pathway, Am J Physiol, 271, C181, 10.1152/ajpcell.1996.271.1.C181 Reddy, 1996, Purified, reconstituted cardiac Ca2+-ATPase is regulated by phospholamban but not by direct phosphorylation with Ca2+/calmodulin-dependent protein kinase, J Biol Chem, 271, 14964, 10.1074/jbc.271.25.14964 Rodriguez, 2004, Critical evaluation of cardiac Ca2+-ATPase phosphorylation on serine 38 using a phosphorylation site-specific antibody, J Biol Chem, 279, 17111, 10.1074/jbc.M400462200 Trebak, 2010, Interplay between calcium and reactive oxygen/nitrogen species: an essential paradigm for vascular smooth muscle signaling, Antioxid Redox Signal, 12, 657, 10.1089/ars.2009.2842 Lu, 2015, Activation of M3 cholinoceptors attenuates vascular injury after ischaemia/reperfusion by inhibiting the Ca2+/calmodulin-dependent protein kinase II pathway, Br J Pharmacol, 172, 5619, 10.1111/bph.13183 Zhu, 2014, Oxidative activation of the Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) regulates vascular smooth muscle migration and apoptosis, Vascul Pharmacol, 60, 75, 10.1016/j.vph.2014.01.001 Scott, 2013, The multifunctional Ca(2)(+)/calmodulin-dependent kinase IIdelta (CaMKIIdelta) regulates arteriogenesis in a mouse model of flow-mediated remodeling, PLoS One, 8, 10.1371/journal.pone.0071550 Pandey, 2011, Calcium/calmodulin-dependent kinase II mediates the phosphorylation and activation of NADPH oxidase 5, Mol Pharmacol, 80, 407, 10.1124/mol.110.070193 Meoli, 2009, Thrombin induces fibronectin-specific migration of pulmonary microvascular endothelial cells: requirement of calcium/calmodulin-dependent protein kinase II, Am J Physiol Lung Cell Mol Physiol, 297, L706, 10.1152/ajplung.90598.2008 Muthalif, 2002, Functional significance of activation of calcium/calmodulin-dependent protein kinase II in angiotensin II–induced vascular hyperplasia and hypertension, Hypertension, 2, 704, 10.1161/hy0202.103823 Prasad, 2015, Calcium/calmodulin-dependent kinase II inhibition in smooth muscle reduces angiotensin II-induced hypertension by controlling aortic remodeling and baroreceptor function, J Am Heart Assoc, 4, 10.1161/JAHA.115.001949 Yousif, 2008, Role of Ca2+/calmodulin-dependent protein kinase II in development of vascular dysfunction in diabetic rats with hypertension, Cell Biochem Funct, 26, 256, 10.1002/cbf.1446 Zander, 2002, Peripheral arterial disease in diabetes mellitus type 1 and type 2: are there different risk factors?, Vasa, 31, 249, 10.1024/0301-1526.31.4.249 Gray, 2017, CaMKIIdelta subtypes differentially regulate infarct formation following ex vivo myocardial ischemia/reperfusion through NF-kappaB and TNF-alpha, J Mol Cell Cardiol, 103, 48, 10.1016/j.yjmcc.2017.01.002 Spinelli, 2015, Smooth muscle CaMKIIdelta promotes allergen-induced airway hyperresponsiveness and inflammation, Pflugers Arch, 467, 2541, 10.1007/s00424-015-1713-5 House, 2008, The non-excitable smooth muscle: calcium signaling and phenotypic switching during vascular disease, Pflugers Arch, 456, 769, 10.1007/s00424-008-0491-8 House, 2008, CaMKII-delta isoform regulation of neointima formation after vascular injury, Arterioscler Thromb Vasc Biol, 28, 441, 10.1161/ATVBAHA.107.156810 Li, 2011, The multifunctional Ca2+/calmodulin-dependent kinase II delta (CaMKIIdelta) controls neointima formation after carotid ligation and vascular smooth muscle cell proliferation through cell cycle regulation by p21, J Biol Chem, 286, 7990, 10.1074/jbc.M110.163006 Wang, 2010, Calcium/calmodulin-dependent protein kinase II delta 6 (CaMKIIdelta6) and RhoA involvement in thrombin-induced endothelial barrier dysfunction, J Biol Chem, 285, 21303, 10.1074/jbc.M110.120790 Murthy, 2017, Endothelial CaMKII as a regulator of eNOS activity and NO-mediated vasoreactivity, PLoS One, 12, 10.1371/journal.pone.0186311 Farb, 1999, Pathology of acute and chronic coronary stenting in humans, Circulation, 99, 44, 10.1161/01.CIR.99.1.44 Saddouk, 2016, Ca2+/calmodulin-dependent protein kinase II-gamma (CaMKIIgamma) negatively regulates vascular smooth muscle cell proliferation and vascular remodeling, FASEB J, 30, 1051, 10.1096/fj.15-279158 Singer, 2012, Ca2+/calmodulin-dependent protein kinase II function in vascular remodelling, J Physiol, 590, 1349, 10.1113/jphysiol.2011.222232 Toussaint, 2016, Vascular CaMKII: heart and brain in your arteries, Am J Physiol Cell Physiol, 311, C462, 10.1152/ajpcell.00341.2015 Louis, 2010, Vascular smooth muscle cell motility: from migration to invasion, Exp Clin Cardiol, 15, e75 Solberg, 2003, A functional overlap of plasminogen and MMPs regulates vascularization during placental development, Development, 130, 4439, 10.1242/dev.00642 Hattori, 2009, MMP-13 plays a role in keratinocyte migration, angiogenesis, and contraction in mouse skin wound healing, Am J Pathol, 175, 533, 10.2353/ajpath.2009.081080 Scott, 2012, The multifunctional Ca2+/calmodulin-dependent kinase II regulates vascular smooth muscle migration through matrix metalloproteinase 9, Am J Physiol Heart Circ Physiol, 302, H1953, 10.1152/ajpheart.00978.2011 Sesso, 2010, Abnormalities in metalloproteinase pathways and IGF-I axis: a link between birth weight, hypertension, and vascular damage in childhood, Am J Hypertens, 23, 6, 10.1038/ajh.2009.200 Tzemos, 2010, Endothelial function, carotid-femoral stiffness, and plasma matrix metalloproteinase-2 in men with bicuspid aortic valve and dilated aorta, J Am Coll Cardiol, 55, 660, 10.1016/j.jacc.2009.08.080 Hidalgo, 2001, Development of matrix metalloproteinase inhibitors in cancer therapy, J Natl Cancer Inst, 93, 178, 10.1093/jnci/93.3.178 Cathcart, 2015, Targeting matrix metalloproteinases in cancer: bringing new life to old ideas, Genes Dis, 2, 26, 10.1016/j.gendis.2014.12.002 Zou, 2002, Oxidation of the zinc-thiolate complex and uncoupling of endothelial nitric oxide synthase by peroxynitrite, J Clin Invest, 109, 817, 10.1172/JCI0214442 Yang, 2009, eNOS uncoupling and endothelial dysfunction in aged vessels, Am J Physiol Heart Circ Physiol, 297, H1829, 10.1152/ajpheart.00230.2009 Raman, 1998, Crystal structure of constitutive endothelial nitric oxide synthase: a paradigm for pterin function involving a novel metal center, Cell, 95, 939, 10.1016/S0092-8674(00)81718-3 Suvorava, 2015, Impact of eNOS-dependent oxidative stress on endothelial function and neointima formation, Antioxid Redox Signal, 23, 711, 10.1089/ars.2014.6059 Muthalif, 2001, Functional interaction of calcium-/calmodulin-dependent protein kinase II and cytosolic phospholipase A(2), J Biol Chem, 276, 39653, 10.1074/jbc.M103136200 Muthalif, 1998, 20-Hydroxyeicosatetraenoic acid mediates calcium/calmodulin-dependent protein kinase II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells, Proc Natl Acad Sci U S A, 95, 12701, 10.1073/pnas.95.21.12701 Liu, 2013, CaMKIIdelta-dependent inhibition of cAMP-response element-binding protein activity in vascular smooth muscle, J Biol Chem, 288, 33519, 10.1074/jbc.M113.490870 Schauer, 2010, CREB downregulation in vascular disease: a common response to cardiovascular risk, Arterioscler Thromb Vasc Biol, 30, 733, 10.1161/ATVBAHA.109.199133 Klemm, 2001, cAMP response element-binding protein content is a molecular determinant of smooth muscle cell proliferation and migration, J Biol Chem, 276, 46132, 10.1074/jbc.M104769200 Ross, 1993, The pathogenesis of atherosclerosis: a perspective for the 1990, Nature, 362, 801, 10.1038/362801a0 Qu, 2017, Oxidized CaMKII promotes asthma through the activation of mast cells, JCI Insight, 2, 10.1172/jci.insight.90139 Liu, 2008, CaMKII promotes TLR-triggered proinflammatory cytokine and type I interferon production by directly binding and activating TAK1 and IRF3 in macrophages, Blood, 112, 4961, 10.1182/blood-2008-03-144022 Pereira, 2008, Wnt5A/CaMKII signaling contributes to the inflammatory response of macrophages and is a target for the antiinflammatory action of activated protein C and interleukin-10, Arterioscler Thromb Vasc Biol, 28, 504, 10.1161/ATVBAHA.107.157438 Zhou, 2014, Calcium/calmodulin-dependent protein kinase II regulates cyclooxygenase-2 expression and prostaglandin E2 production by activating cAMP-response element-binding protein in rat peritoneal macrophages, Immunology, 143, 287, 10.1111/imm.12309 Weinreuter, 2014, CaM kinase II mediates maladaptive post-infarct remodeling and pro-inflammatory chemoattractant signaling but not acute myocardial ischemia/reperfusion injury, EMBO Mol Med, 6, 1231, 10.15252/emmm.201403848 Timmins, 2009, Calcium/calmodulin-dependent protein kinase II links ER stress with Fas and mitochondrial apoptosis pathways, J Clin Invest, 119, 2925, 10.1172/JCI38857 Maione, 2017, Cellular subtype expression and activation of CaMKII regulate the fate of atherosclerotic plaque, Atherosclerosis, 256, 53, 10.1016/j.atherosclerosis.2016.11.006