Ca2+ signaling is critical for pancreatic stellate cell’s pathophysiology : from fibrosis to cancer hallmarks

Current Opinion in Physiology - Tập 17 - Trang 255-260 - 2020
Silviya Radoslavova1,2, Halima Ouadid-Ahidouch1, Natalia Prevarskaya2
1Laboratory of Cellular and Molecular Physiology, UR 4667, University of Picardie Jules Verne, Amiens, France
2Laboratory of Cell Physiology, INSERM U1003, Laboratory of Excellence, Ion Channels Science and Therapeutics, University of Lille 1, Villeneuve d’Ascq, France

Tài liệu tham khảo

Apte, 2015, Pancreatic stellate cell: physiologic role, role in fibrosis and cancer, Curr Opin Gastroenterol, 31, 416, 10.1097/MOG.0000000000000196 Bachem, 1998, Identification, culture, and characterization of pancreatic stellate cells in rats and humans, Gastroenterology, 115, 421, 10.1016/S0016-5085(98)70209-4 Apte, 2004, Desmoplastic reaction in pancreatic cancer: role of pancreatic stellate cells, Pancreas, 29, 179, 10.1097/00006676-200410000-00002 Berridge, 1998, Calcium - a life and death signal, Nature, 395, 645, 10.1038/27094 Petersen, 2005, Calcium signalling: past present and future, Cell Calcium, 38, 161, 10.1016/j.ceca.2005.06.023 Apte, 1998, Periacinar stellate shaped cells in rat pancreas: identification, isolation, and culture, Gut, 43, 128, 10.1136/gut.43.1.128 McCarroll, 2006, Vitamin A inhibits pancreatic stellate cell activation: implications for treatment of pancreatic fibrosis, Gut, 55, 79, 10.1136/gut.2005.064543 Phillips, 2010, Pancreatic stellate cells produce acetylcholine and may play a role in pancreatic exocrine secretion, Proc Natl Acad Sci U S A, 107, 17397, 10.1073/pnas.1000359107 Masamune, 2008, Pancreatic stellate cells express toll-like receptors, J Gastroenterol, 43, 352, 10.1007/s00535-008-2162-0 Ferdek, 2017, Biology of pancreatic stellate cells—more than just pancreatic cancer, Pflugers Arch, 469, 1039, 10.1007/s00424-017-1968-0 Jaster, 2008, Crucial role of fibrogenesis in pancreatic diseases, Best Pract Res Clin Gastroenterol, 22, 17, 10.1016/j.bpg.2007.10.004 Apte, 2012, Pancreatic stellate cells: a starring role in normal and diseased pancreas, Front Physiol, 3, 10.3389/fphys.2012.00344 Apte, 1999, Pancreatic stellate cells are activated by proinflammatory cytokines: implications for pancreatic fibrogenesis, Gut, 44, 534, 10.1136/gut.44.4.534 Schneider, 2001, Identification of mediators stimulating proliferation and matrix synthesis of rat pancreatic stellate cells, Am J Physiol-Cell Physiol, 281, C532, 10.1152/ajpcell.2001.281.2.C532 Vogelmann, 2001, Effects of fibrogenic mediators on the development of pancreatic fibrosis in a TGF-β1 transgenic mouse model, Am J Physiol-Gastrointest Liver Physiol, 280, G164, 10.1152/ajpgi.2001.280.1.G164 Shimada, 2002, IL-6 secretion by human pancreatic periacinar myofibroblasts in response to inflammatory mediators, J Immunol Baltim Md 1950, 168, 861 Apte, 2000, Does alcohol directly stimulate pancreatic fibrogenesis? Studies with rat pancreatic stellate cells, Gastroenterology, 118, 780, 10.1016/S0016-5085(00)70148-X Gryshchenko, 2018, Calcium signalling in the acinar environment of the exocrine pancreas: physiology and pathophysiology, J Physiol, 596, 2663, 10.1113/JP275395 Gryshchenko, 2016, Ca2+ signals mediated by bradykinin type 2 receptors in normal pancreatic stellate cells can be inhibited by specific Ca2+ channel blockade, J Physiol, 594, 281, 10.1113/JP271468 Ferdek, 2016, Bile acids induce necrosis in pancreatic stellate cells dependent on calcium entry and sodium‐driven bile uptake, J Physiol, 594, 6147, 10.1113/JP272774 Won, 2011, Phenotypic changes in mouse pancreatic stellate cell Ca2+ signaling events following activation in culture and in a disease model of pancreatitis, Mol Biol Cell, 22, 421, 10.1091/mbc.e10-10-0807 Klonowski-Stumpe, 2003, Production and effects of endothelin-1 in rat pancreatic stellate cells, Pancreas, 27, 67, 10.1097/00006676-200307000-00010 Reinehr, 2004, Effects of angiotensin II on rat pancreatic stellate cells, Pancreas, 28, 129, 10.1097/00006676-200403000-00003 Masamune, 2008, Hypoxia stimulates pancreatic stellate cells to induce fibrosis and angiogenesis in pancreatic cancer, Am J Physiol Gastrointest Liver Physiol, 295, G709, 10.1152/ajpgi.90356.2008 Luttenberger, 2000, Platelet-derived growth factors stimulate proliferation and extracellular matrix synthesis of pancreatic stellate cells: implications in pathogenesis of pancreas fibrosis, Lab Investig J Tech Methods Pathol, 80, 47, 10.1038/labinvest.3780007 Allam, 2017, Pancreatic stellate cells in pancreatic cancer: i focus, Pancreatol Off J Int Assoc Pancreatol IAP Al, 17, 514 Hegyi, 2018, Necrotic amplification loop in acute pancreatitis: pancreatic stellate cells and nitric oxide are important players in the development of the disease, J Physiol, 596, 2679, 10.1113/JP275930 Gerasimenko, 2018, Ca2+ signalling underlying pancreatitis, Cell Calcium, 70, 95, 10.1016/j.ceca.2017.05.010 Gerasimenko, 2013, Ca2+ release-activated Ca2+ channel blockade as a potential tool in antipancreatitis therapy, Proc Natl Acad Sci U S A, 110, 13186, 10.1073/pnas.1300910110 Norton, 2020, Pancreatic cancer associated fibroblasts (CAF): under-explored target for pancreatic cancer treatment, Cancers, 12, 10.3390/cancers12051347 Pereira, 2019, CAF subpopulations: a new reservoir of stromal targets in pancreatic cancer, Trends Cancer, 5, 724, 10.1016/j.trecan.2019.09.010 Öhlund, 2017, Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer, J Exp Med, 214, 579, 10.1084/jem.20162024 Neuzillet, 2019, Inter‐ and intra‐tumoural heterogeneity in cancer‐associated fibroblasts of human pancreatic ductal adenocarcinoma, J Pathol, 248, 51, 10.1002/path.5224 Habisch, 2010, Interaction of stellate cells with pancreatic carcinoma cells, Cancers, 2, 1661, 10.3390/cancers2031661 Vonlaufen, 2008, Pancreatic stellate cells: partners in crime with pancreatic cancer cells, Cancer Res, 68, 2085, 10.1158/0008-5472.CAN-07-2477 Sousa, 2016, Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion, Nature, 536, 479, 10.1038/nature19084 Schneiderhan, 2007, Pancreatic stellate cells are an important source of MMP-2 in human pancreatic cancer and accelerate tumor progression in a murine xenograft model and CAM assay, J Cell Sci, 120, 512, 10.1242/jcs.03347 Hwang, 2008, Cancer-associated stromal fibroblasts promote pancreatic tumor progression, Cancer Res, 68, 918, 10.1158/0008-5472.CAN-07-5714 Jakubowska, 2016, Nitric oxide signals are interlinked with calcium signals in normal pancreatic stellate cells upon oxidative stress and inflammation, Open Biol, 6, 10.1098/rsob.160149 Hennigs, 2011, Molecular basis of P2-receptor-mediated calcium signaling in activated pancreatic stellate cells, Pancreas, 40, 740, 10.1097/MPA.0b013e31821b5b68 Haanes, 2012, The P2X7 receptor supports both life and death in fibrogenic pancreatic stellate cells, PLoS One, 7, 10.1371/journal.pone.0051164 Giannuzzo, 2016, Targeting of the P2X7 receptor in pancreatic cancer and stellate cells, Int J Cancer, 139, 2540, 10.1002/ijc.30380 Santofimia-Castaño, 2015, Melatonin induces calcium mobilization and influences cell proliferation independently of MT1/MT2 receptor activation in rat pancreatic stellate cells, Cell Biol Toxicol, 31, 95, 10.1007/s10565-015-9297-6 Estaras, 2019, Melatonin induces reactive oxygen species generation and changes in glutathione levels and reduces viability in human pancreatic stellate cells, J Physiol Biochem, 75, 185, 10.1007/s13105-019-00671-x Martínez-Morcillo, 2019, The organophosphorus pesticide dimethoate decreases cell viability and induces changes in different biochemical parameters of rat pancreatic stellate cells, Toxicol In Vitro, 54, 89, 10.1016/j.tiv.2018.09.011 Zhang, 2013, Prolonged high fat/alcohol exposure increases TRPV4 and its functional responses in pancreatic stellate cells, Am J Physiol - Regul Integr Comp Physiol, 304, R702, 10.1152/ajpregu.00296.2012 Waldron, 2019, The Orai Ca2+ channel inhibitor CM4620 targets both parenchymal and immune cells to reduce inflammation in experimental acute pancreatitis, J Physiol, 597, 3085, 10.1113/JP277856 Fels, 2016, Role of TRPC1 channels in pressure-mediated activation of murine pancreatic stellate cells, Eur Biophys J, 45, 657, 10.1007/s00249-016-1176-4 Nielsen, 2017, TRPC6 channels modulate the response of pancreatic stellate cells to hypoxia, Pflüg Arch - Eur J Physiol, 469, 1567, 10.1007/s00424-017-2057-0 Storck, 2016, Ion channels in control of pancreatic stellate cell migration, Oncotarget, 8, 769, 10.18632/oncotarget.13647 Kuntze, 2020, Protonation of Piezo1 impairs cell-matrix interactions of pancreatic stellate cells, Front Physiol, 11, 10.3389/fphys.2020.00089