CTRP family: linking immunity to metabolism

Wong, 2004, A family of Acrp30/adiponectin structural and functional paralogs, Proc. Natl. Acad. Sci. U.S.A., 101, 10302, 10.1073/pnas.0403760101 Kishore, 2004, C1q and tumor necrosis factor superfamily: modularity and versatility, Trends Immunol., 25, 551, 10.1016/j.it.2004.08.006 Shapiro, 1998, The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor, Curr. Biol., 8, 335, 10.1016/S0960-9822(98)70133-2 Ghai, 2007, C1q and its growing family, Immunobiology, 212, 253, 10.1016/j.imbio.2006.11.001 Schaffler, 2003, Genomic organization, promoter, amino acid sequence, chromosomal localization, and expression of the human gene for CORS-26 (collagenous repeat-containing sequence of 26-kDa protein), Biochim. Biophys. Acta, 1630, 123, 10.1016/j.bbaexp.2003.08.013 Schaffler, 2003, Genomic organization, chromosomal localization and adipocytic expression of the murine gene for CORS-26 (collagenous repeat-containing sequence of 26 kDa protein), Biochim. Biophys. Acta, 1628, 64, 10.1016/S0167-4781(03)00114-3 Maeda, 2001, Molecular cloning and characterization of a novel gene, CORS26, encoding a putative secretory protein and its possible involvement in skeletal development, J. Biol. Chem., 276, 3628, 10.1074/jbc.M007898200 Schaffler, 2004, Role of specificity protein-1, PPARgamma, and pituitary protein transcription factor-1 in transcriptional regulation of the murine CORS-26 promoter, Biochim. Biophys. Acta, 1678, 150, 10.1016/j.bbaexp.2004.02.006 Innamorati, 2002, GIP, a G-protein-coupled receptor interacting protein, Regul. Pept., 109, 173, 10.1016/S0167-0115(02)00201-X Wong, 2008, Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions, Biochem. J., 416, 161, 10.1042/BJ20081240 Kim, 2006, Tumor necrosis factor-alpha and interleukin-1beta increases CTRP1 expression in adipose tissue, FEBS Lett., 580, 3953, 10.1016/j.febslet.2006.06.034 Jeon, 2008, A novel adipokine CTRP1 stimulates aldosterone production, FASEB J., 22, 1502, 10.1096/fj.07-9412com Wong, 2009, Identification and characterization of CTRP9, a novel secreted glycoprotein, from adipose tissue that reduces serum glucose in mice and forms heterotrimers with adiponectin, FASEB J., 23, 241, 10.1096/fj.08-114991 Calmont, 2000, Identification of a short cis-acting element in the human vasopressin type 2 receptor gene which confers high-level expression of a reporter gene specifically in collecting duct cells, Mol. Endocrinol., 14, 1682, 10.1210/me.14.10.1682 Schrier, 2006, Optimal care of autosomal dominant polycystic kidney disease patients, Nephrology (Carlton), 11, 124, 10.1111/j.1440-1797.2006.00535.x Cooper, 1997, ACE, angiotensinogen and obesity: a potential pathway leading to hypertension, J. Hum. Hypertens., 11, 107, 10.1038/sj.jhh.1000391 Lasser, 2006, C1qTNF-related protein-1 (CTRP-1): a vascular wall protein that inhibits collagen-induced platelet aggregation by blocking VWF binding to collagen, Blood, 107, 423, 10.1182/blood-2005-04-1425 Maeda, 2001, PPARgamma ligands increase expression and plasma concentrations of adiponectin, an adipose-derived protein, Diabetes, 50, 2094, 10.2337/diabetes.50.9.2094 Li, 2011, High level expression, purification and characterization of active fusion human C1q and tumor necrosis factor related protein 2 (hCTRP2) in Escherichia coli, Protein Expr. Purif., 79, 1, 10.1016/j.pep.2011.03.013 Weigert, 2005, The adiponectin paralog CORS-26 has anti-inflammatory properties and is produced by human monocytic cells, FEBS Lett., 579, 5565, 10.1016/j.febslet.2005.09.022 Peterson, 2011, C1q/TNF-related protein-3 (CTRP3), a novel adipokine that regulates hepatic glucose output, J. Biol. Chem., 285, 39691, 10.1074/jbc.M110.180695 Wurm, 2007, Plasma levels of leptin, omentin, collagenous repeat-containing sequence of 26-kDa protein (CORS-26) and adiponectin before and after oral glucose uptake in slim adults, Cardiovasc. Diabetol., 6, 7, 10.1186/1475-2840-6-7 Wiest, 2009, Peritoneal fluid adipokines: ready for prime time?, Eur. J. Clin. Invest., 39, 219, 10.1111/j.1365-2362.2009.02085.x Hofmann, 2011, C1q/TNF-related protein-3 (CTRP-3) is secreted by visceral adipose tissue and exerts antiinflammatory and antifibrotic effects in primary human colonic fibroblasts, Inflamm. Bowel Dis., 17, 2462, 10.1002/ibd.21647 Kopp, 2010, C1q/TNF-related protein-3 represents a novel and endogenous lipopolysaccharide antagonist of the adipose tissue, Endocrinology, 151, 5267, 10.1210/en.2010-0571 Schaffler, 2007, Regulation and function of collagenous repeat containing sequence of 26-kDa protein gene product ‘cartonectin’, Obesity (Silver Spring), 15, 303, 10.1038/oby.2007.566 Maeda, 2006, Cartducin, a paralog of Acrp30/adiponectin, is induced during chondrogenic differentiation and promotes proliferation of chondrogenic precursors and chondrocytes, J. Cell Physiol., 206, 537, 10.1002/jcp.20493 Akiyama, 2007, CTRP3/cartducin promotes proliferation and migration of endothelial cells, Mol. Cell. Biochem., 304, 243, 10.1007/s11010-007-9506-6 Akiyama, 2006, Cartducin stimulates mesenchymal chondroprogenitor cell proliferation through both extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways, FEBS J., 273, 2257, 10.1111/j.1742-4658.2006.05240.x Li, 2007, Temporal evolution of gene expression in rat carotid artery following balloon angioplasty, J. Cell Biochem., 101, 399, 10.1002/jcb.21190 Compton, 2010, CTRP-3: blocking a toll booth to obesity-related inflammation, Endocrinology, 151, 5095, 10.1210/en.2010-0916 Kopp, 2011, Effects of the new adiponectin paralogous protein CTRP-3 and of LPS on cytokine release from monocytes of patients with type 2 diabetes mellitus, Cytokine, 49, 51, 10.1016/j.cyto.2009.10.001 Wolfing, 2008, Effects of the new C1q/TNF-related protein (CTRP-3) ‘cartonectin’ on the adipocytic secretion of adipokines, Obesity (Silver Spring), 16, 1481, 10.1038/oby.2008.206 Snoussi, 2006, Leptin and leptin receptor polymorphisms are associated with increased risk and poor prognosis of breast carcinoma, BMC Cancer, 6, 38, 10.1186/1471-2407-6-38 Li, 2011, Identification of C1qTNF-related protein 4 as a potential cytokine that stimulates the STAT3 and NF-kappaB pathways and promotes cell survival in human cancer cells, Cancer Lett., 308, 203, 10.1016/j.canlet.2011.05.005 Lee, 2005, Microarray profiling of isolated abdominal subcutaneous adipocytes from obese vs non-obese Pima Indians: increased expression of inflammation-related genes, Diabetologia, 48, 1776, 10.1007/s00125-005-1867-3 Ayyagari, 2005, Late-onset macular degeneration and long anterior lens zonules result from a CTRP5 gene mutation, Invest. Ophthalmol. Vis. Sci., 46, 3363, 10.1167/iovs.05-0159 Mandal, 2006, CTRP5 is a membrane-associated and secretory protein in the RPE and ciliary body and the S163R mutation of CTRP5 impairs its secretion, Invest. Ophthalmol. Vis. Sci., 47, 5505, 10.1167/iovs.06-0312 Park, 2009, C1q tumor necrosis factor alpha-related protein isoform 5 is increased in mitochondrial DNA-depleted myocytes and activates AMP-activated protein kinase, J. Biol. Chem., 284, 27780, 10.1074/jbc.M109.005611 Yamauchi, 2003, Cloning of adiponectin receptors that mediate antidiabetic metabolic effects, Nature, 423, 762, 10.1038/nature01705 Yamada, 2008, Genetic risk for metabolic syndrome: examination of candidate gene polymorphisms related to lipid metabolism in Japanese people, J. Med. Genet., 45, 22, 10.1136/jmg.2007.052415 Hayward, 2003, Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration, Hum. Mol. Genet., 12, 2657, 10.1093/hmg/ddg289 Borooah, 2009, Late-onset retinal macular degeneration: clinical insights into an inherited retinal degeneration, Postgrad. Med. J., 85, 495, 10.1136/bjo.2008.150151 Shu, 2006, Disease mechanisms in late-onset retinal macular degeneration associated with mutation in C1QTNF5, Hum. Mol. Genet., 15, 1680, 10.1093/hmg/ddl091 Chavali, 2011, A CTRP5 gene S163R mutation knock-in mouse model for late-onset retinal degeneration, Hum. Mol. Genet., 20, 2000, 10.1093/hmg/ddr080 Mandal, 2006, Spatial and temporal expression of MFRP and its interaction with CTRP5, Invest. Ophthalmol. Vis. Sci., 47, 5514, 10.1167/iovs.06-0449 Kim, 2011, C1qTNF-related protein-6 increases the expression of interleukin-10 in macrophages, Mol. Cells, 30, 59, 10.1007/s10059-010-0088-x Eyre, 2011, Overlapping genetic susceptibility variants between three autoimmune disorders: rheumatoid arthritis, type 1 diabetes and coeliac disease, Arthritis Res. Ther., 12, R175, 10.1186/ar3139 Wallis, 2009, Type 1 diabetes in the BB rat: a polygenic disease, Diabetes, 58, 1007, 10.2337/db08-1215 Cooper, 2008, Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci, Nat. Genet., 40, 1399, 10.1038/ng.249 Jin, 2011, Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo, N. Engl. J. Med., 362, 1686, 10.1056/NEJMoa0908547 Takeuchi, 2011, Expression of a secretory protein C1qTNF6, a C1qTNF family member, in hepatocellular carcinoma, Anal. Cell. Pathol. (Amst.), 34, 113, 10.1155/2011/578097 Dick, 2011, Genome-wide association study of conduct disorder symptomatology, Mol. Psychiatry, 16, 800, 10.1038/mp.2010.73 Peterson, 2009, CTRP8 and CTRP9B are novel proteins that hetero-oligomerize with C1q/TNF family members, Biochem. Biophys. Res. Commun., 388, 360, 10.1016/j.bbrc.2009.08.014 Berube, 1999, Cloning and characterization of CRF, a novel C1q-related factor, expressed in areas of the brain involved in motor function, Brain Res. Mol. Brain Res., 63, 233, 10.1016/S0169-328X(98)00278-2 Chacko, 2011, Magnesium supplementation, metabolic and inflammatory markers, and global genomic and proteomic profiling: a randomized, double-blind, controlled, crossover trial in overweight individuals, Am. J. Clin. Nutr., 93, 463, 10.3945/ajcn.110.002949 Zheng, 2011, C1q/TNF-related proteins, a family of novel adipokines, induce vascular relaxation through the adiponectin receptor-1/AMPK/eNOS/nitric oxide signaling pathway, Arterioscler. Thromb. Vasc. Biol., 31, 2616, 10.1161/ATVBAHA.111.231050 Wei, 2011, Metabolic regulation by C1q/TNF-related protein-13 (CTRP13): activation of AMP-activated protein kinase and suppression of fatty acid-induced JNK signaling, J. Biol. Chem., 286, 15652, 10.1074/jbc.M110.201087 Wobser, 2009, Lipid accumulation in hepatocytes induces fibrogenic activation of hepatic stellate cells, Cell Res., 19, 996, 10.1038/cr.2009.73 Wanninger, 2011, Lipid accumulation impairs adiponectin-mediated induction of activin A by increasing TGFbeta in primary human hepatocytes, Biochim. Biophys. Acta, 1811, 626, 10.1016/j.bbalip.2010.11.001 Davis, 2008, Adiponectin: no longer the lone soul in the fight against insulin resistance?, Biochem. J., 416, e7, 10.1042/BJ20082033 Shimomura, 1996, Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity, Nat. Med., 2, 800, 10.1038/nm0796-800 Tsao, 2003, Role of disulfide bonds in Acrp30/adiponectin structure and signaling specificity. Different oligomers activate different signal transduction pathways, J. Biol. Chem., 278, 50810, 10.1074/jbc.M309469200 Kadowaki, 2005, Adiponectin and adiponectin receptors, Endocr. Rev., 26, 439, 10.1210/er.2005-0005 Maeda, 1996, cDNA cloning and expression of a novel adipose specific collagen-like factor, apM1 (adipose most abundant gene transcript 1), Biochem. Biophys. Res. Commun., 221, 286, 10.1006/bbrc.1996.0587 Basu, 2007, Selective downregulation of the high molecular weight form of adiponectin in hyperinsulinemia and in type 2 diabetes: differential regulation from nondiabetic subjects, Diabetes, 56, 2174, 10.2337/db07-0185 Pajvani, 2004, Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity, J. Biol. Chem., 279, 12152, 10.1074/jbc.M311113200 Waki, 2003, Impaired multimerization of human adiponectin mutants associated with diabetes. Molecular structure and multimer formation of adiponectin, J. Biol. Chem., 278, 40352, 10.1074/jbc.M300365200 Wang, 2008, Adiponectin, cardiovascular function, and hypertension, Hypertension, 51, 8, 10.1161/HYPERTENSIONAHA.107.099424 Barseghian, 2011, Adiponectin and vulnerable atherosclerotic plaques, J. Am. Coll. Cardiol., 57, 761, 10.1016/j.jacc.2010.11.011 Kadowaki, 2006, Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome, J. Clin. Invest., 116, 1784, 10.1172/JCI29126 Lo, 2011, Adiponectin, cardiovascular disease, chronic kidney disease: emerging data on complex interactions, Pediatr. Nephrol., 10.1007/s00467-011-1906-x Ouchi, 2011, Adipokines in inflammation and metabolic disease, Nat. Rev. Immunol., 11, 85, 10.1038/nri2921 Schäffler, 2005, Mechanism of disease: adipocytokines and visceral adipose tissue: emerging role in non-alcoholic fatty liver disease, Nat. Clin. Pract. (Gastroenterol. Hepatol.), 2, 273, 10.1038/ncpgasthep0186 Scherer, 2006, Adipose tissue: from lipid storage compartment to endocrine organ, Diabetes, 55, 1537, 10.2337/db06-0263 Stenvinkel, 2011, Adiponectin in chronic kidney disease: a complex and context sensitive clinical situation, J. Ren. Nutr., 21, 82, 10.1053/j.jrn.2010.10.019 Abke, 2006, Adiponectin-induced secretion of interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1, CCL2) and interleukin-8 (IL-8, CXCL8) is impaired in monocytes from patients with type I diabetes, Cardiovasc. Diabetol., 5, 17, 10.1186/1475-2840-5-17 Weigert, 2009, Circulating levels of chemerin and adiponectin are higher in ulcerative colitis and chemerin is elevated in Crohn's disease, Inflamm. Bowel Dis., 16, 630, 10.1002/ibd.21091 Van Berendoncks, 2010, Exercise training reduces circulating adiponectin levels in patients with chronic heart failure, Clin. Sci. (Lond)., 118, 281, 10.1042/CS20090213 Fayad, 2007, Adiponectin deficiency protects mice from chemically induced colonic inflammation, Gastroenterology, 132, 601, 10.1053/j.gastro.2006.11.026 Frommer, 2010, Adiponectin-mediated changes in effector cells involved in the pathophysiology of rheumatoid arthritis, Arthritis Rheum., 62, 2886, 10.1002/art.27616 Neumeier, 2006, Different effects of adiponectin isoforms in human monocytic cells, J. Leukoc. Biol., 75, 803, 10.1189/jlb.0905521 Zhang, 1994, Positional cloning of the mouse obese gene and its human homologue, Nature, 372, 425, 10.1038/372425a0 Tartaglia, 1995, Identification and expression cloning of a leptin receptor, OB-R, Cell, 83, 1263, 10.1016/0092-8674(95)90151-5 Murakami, 1995, Cloning of rat obese cDNA and its expression in obese rats, Biochem. Biophys. Res. Commun., 209, 944, 10.1006/bbrc.1995.1589 Ogawa, 1995, Molecular cloning of rat obese cDNA and augmented gene expression in genetically obese Zucker fatty (fa/fa) rats, J. Clin. Invest., 96, 1647, 10.1172/JCI118204 Shima, 1996, Exercise training has a long-lasting effect on prevention of non-insulin-dependent diabetes mellitus in Otsuka Long–Evans–Tokushima fatty rats, Metabolism, 45, 475, 10.1016/S0026-0495(96)90222-X