CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes

Cell - Tập 154 Số 2 - Trang 442-451 - 2013
Luke A. Gilbert1,2,3,4, Matthew H. Larson1,2,3,4, Leonardo Morsut3,4, Zairan Liu5, Gloria A. Brar1,2,3,4, Sandra E. Torres1,2,3,4, Noam Stern‐Ginossar1,2,3,4, Onn Brandman1,2,3,4, Evan H. Whitehead1,3,6, Jennifer A. Doudna1,2,7,8,9,4,10, Wendell A. Lim1,3,4,6, Jonathan S. Weissman1,2,3,4,6, Lei S. Qi1,3,6
1California Institute for Quantitative Biomedical Research, San Francisco, CA 94158, USA
2Center for RNA Systems Biology, University of California, Berkeley, Berkeley, CA 94720, USA
3Department of Cellular and Molecular Pharmacology, University of California San Francisco, San Francisco, CA 94158, USA
4Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94158, USA
5Peking University, Beijing, China
6UCSF Center for Systems and Synthetic Biology, University of California, San Francisco, San Francisco, CA 94158, USA
7Department of Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA
8Department of Chemistry, University of California, Berkeley, Berkeley, CA 94720 USA
9Department of Molecular and Cellular Biology, University of California Berkeley, Berkeley, CA 94720, USA
10Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA 94720, USA

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