CLINICAL AND LABORATORY EVALUATION OF AIDS TRICHOPATHY

International Journal of Dermatology - Tập 32 Số 1 - Trang 33-38 - 1993
Neil S. Sadick1
1Department of Medicine, Cornell University Medical College, New York, New York.

Tóm tắt

Abstract Background. The present study reports the incidence of trichocutaneous disorders studied in 500 patients infected with HIV I in a large university‐based setting. Correlation of these findings with immunologic function at the time of diagnosis is presented. Unusual presentations and therapeutic interventions are discussed. Prognosis as related to various trichocutaneous disorders is elaborated. Methods. All patients in this study were hivi positive by Western blot assay. T‐cell subsets were evaluated by monoclonal antibodies against T‐cell surface markers. Hair disorders were analyzed by means of light hair pull test, hair mount, polarizing microscopy, trichogram, scalp biophsy, and cultures for bacteria, fungi, and mycobacteria as indicated. Trichologic manifestations were classified based upon immunologic correlation of absolute level of helper T cells/mm3. Results. The majority of hair disorders in the study population occurred with helper T cell numbers of less than 150/mm3. Papulosquamous problems including seborrheic dermatitis and psoriasis were most commonly noted followed by disorders of cell growth cycle regulation and trichokeratinization, i.e., telogen effluvium and loose anagen syndrome. Conclusions. Multiple trichocutaneous disorders occur in the setting of retroviral infection. Most of these disorders occur in the setting of progressive immunoincompetence. The awareness of the disorders described here will aid the clinician in both the recognition and management of pilar aberrations in the appropriate clinical setting.

Từ khóa


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International Journal of Dermatology

Tập 32 Số 1

33-38

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