CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

Nature - Tập 569 Số 7755 - Trang 270-274 - 2019
Xiaogang Wang1, Michael D. Green2, Yuanyuan Qiao2, Miguel A. Gijón3, Paul D. Kennedy3, Jeffrey Johnson3, Peng Liao1, Xueting Lang1, Ilona Kryczek1, Amanda Sell1, Houjun Xia2, Jiajia Zhou1, Gaopeng Li1, Jing Li2, Wei Li1, Shuang Wei2, Linda Vatan2, Xiaohui Zhang2, Wojciech Szeliga2, Wei Gu4, Rebecca Liu5, Theodore S. Lawrence6, Candice Lamb7, Yuri Tanno7, Marcin Cieślik8, Everett Stone7, George Georgiou7, Timothy A. Chan9, Arul M. Chinnaiyan8, Weiping Zou2
1Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI, USA
2Center of Excellence for Cancer Immunology and Immunotherapy, University of Michigan Rogel Cancer Center, University of Michigan School of Medicine, Ann Arbor, MI, USA
3Cayman Chemical Company, Ann Arbor, MI, USA
4Institute for Cancer Genetics, Department of Pathology and Cell Biology, and Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeons, Columbia University, New York, NY, USA
5Department of Obstetrics and Gynecology, University of Michigan School of Medicine, Ann Arbor, MI, USA
6Department of Radiation Oncology, University of Michigan School of Medicine, Ann Arbor, MI, USA
7Department of Chemical Engineering, University of Texas at Austin, Austin, TX, USA
8Department of Pathology, University of Michigan School of Medicine, Ann Arbor, MI USA
9Immunogenomics and Precision Oncology Platform, Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY, USA

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