CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response
Tài liệu tham khảo
Benjamini, 1995, Controlling the false discovery rate: a practical and powerful approach to multiple testing, J. R. Stat. Soc. B, 57, 289
Bruzzone, 2009, Catastrophic NAD+ depletion in activated T lymphocytes through Nampt inhibition reduces demyelination and disability in EAE, PLoS One, 4, e7897, 10.1371/journal.pone.0007897
Buck, 2016, Mitochondrial dynamics controls T cell fate through metabolic programming, Cell, 166, 63, 10.1016/j.cell.2016.05.035
Buck, 2015, T cell metabolism drives immunity, J. Exp. Med., 212, 1345, 10.1084/jem.20151159
Camacho-Pereira, 2016, CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism, Cell Metab., 23, 1127, 10.1016/j.cmet.2016.05.006
Caro-Maldonado, 2012, Matched and mismatched metabolic fuels in lymphocyte function, Semin. Immunol., 24, 405, 10.1016/j.smim.2012.12.002
Chang, 2013, Posttranscriptional control of T cell effector function by aerobic glycolysis, Cell, 153, 1239, 10.1016/j.cell.2013.05.016
Chang, 2016, Emerging concepts of T cell metabolism as a target of immunotherapy, Nat. Immunol., 17, 364, 10.1038/ni.3415
Chatterjee, 2014, Reducing CD73 expression by IL1β-Programmed Th17 cells improves immunotherapeutic control of tumors, Cancer Res., 74, 6048, 10.1158/0008-5472.CAN-14-1450
Chen, 2009, ToppGene Suite for gene list enrichment analysis and candidate gene prioritization, Nucleic Acids Res., 37, W305, 10.1093/nar/gkp427
Chini, 2009, CD38 as a regulator of cellular NAD: a novel potential pharmacological target for metabolic conditions, Curr. Pharm. Des., 15, 57, 10.2174/138161209787185788
Crompton, 2014, Reprogramming antitumor immunity, Trends Immunol., 35, 178, 10.1016/j.it.2014.02.003
Daitoku, 2004, Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity, Proc. Natl. Acad. Sci. USA, 101, 10042, 10.1073/pnas.0400593101
Daitoku, 2011, Regulation of FoxO transcription factors by acetylation and protein-protein interactions, Biochim. Biophys. Acta, 1813, 1954, 10.1016/j.bbamcr.2011.03.001
Daitoku, 2003, Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR, Diabetes, 52, 642, 10.2337/diabetes.52.3.642
Doedens, 2013, Hypoxia-inducible factors enhance the effector responses of CD8(+) T cells to persistent antigen, Nat. Immunol., 14, 1173, 10.1038/ni.2714
Emtage, 2003, Generating potent Th1/Tc1 T cell adoptive immunotherapy doses using human IL-12: Harnessing the immunomodulatory potential of IL-12 without the in vivo-associated toxicity, J. Immunother., 26, 97, 10.1097/00002371-200303000-00002
Gerriets, 2015, Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation, J. Clin. Invest., 125, 194, 10.1172/JCI76012
Gubbels Bupp, 2009, T cells require Foxo1 to populate the peripheral lymphoid organs, Eur. J. Immunol., 39, 2991, 10.1002/eji.200939427
Harrington, 2008, Memory CD4 T cells emerge from effector T-cell progenitors, Nature, 452, 356, 10.1038/nature06672
Hess Michelini, 2013, Differentiation of CD8 memory T cells depends on Foxo1, J. Exp. Med., 210, 1189, 10.1084/jem.20130392
Jogl, 2004, Structure and function of carnitine acyltransferases, Ann. N. Y. Acad. Sci., 1033, 17, 10.1196/annals.1320.002
Kerkar, 2011, Genetic engineering of murine CD8+ and CD4+ T cells for preclinical adoptive immunotherapy studies, J. Immunother., 34, 343, 10.1097/CJI.0b013e3182187600
Klysz, 2015, Glutamine-dependent α-ketoglutarate production regulates the balance between T helper 1 cell and regulatory T cell generation, Sci. Signal., 8, ra97, 10.1126/scisignal.aab2610
Koya, 2010, Kinetic phases of distribution and tumor targeting by T cell receptor engineered lymphocytes inducing robust antitumor responses, Proc. Natl. Acad. Sci. USA, 107, 14286, 10.1073/pnas.1008300107
Kryczek, 2011, Human TH17 cells are long-lived effector memory cells, Sci. Transl. Med., 3, 104ra100, 10.1126/scitranslmed.3002949
Le, 2012, Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells, Cell Metab., 15, 110, 10.1016/j.cmet.2011.12.009
Lee, 2012, Induction and molecular signature of pathogenic TH17 cells, Nat. Immunol., 13, 991, 10.1038/ni.2416
Li, 2013, SIRT1 and energy metabolism, Acta Biochim. Biophys. Sin. (Shanghai), 45, 51, 10.1093/abbs/gms108
Lord, 2005, T-bet is required for optimal proinflammatory CD4+ T-cell trafficking, Blood, 106, 3432, 10.1182/blood-2005-04-1393
Lu, 2012, Th9 cells promote antitumor immune responses in vivo, J. Clin. Invest., 122, 4160, 10.1172/JCI65459
Mehrotra, 2012, A coreceptor-independent transgenic human TCR mediates anti-tumor and anti-self immunity in mice, J. Immunol., 189, 1627, 10.4049/jimmunol.1103271
Meyerhof, 1951, Mechanisms of glycolysis and fermentation, Can. J. Med. Sci., 29, 63
Morandi, 2015, A non-canonical adenosinergic pathway led by CD38 in human melanoma cells induces suppression of T cell proliferation, Oncotarget, 6, 25602, 10.18632/oncotarget.4693
Mullen, 2002, Hlx is induced by and genetically interacts with T-bet to promote heritable T(H)1 gene induction, Nat. Immunol., 3, 652, 10.1038/ni807
Muranski, 2008, Tumor-specific Th17-polarized cells eradicate large established melanoma, Blood, 112, 362, 10.1182/blood-2007-11-120998
Muranski, 2011, Th17 cells are long lived and retain a stem cell-like molecular signature, Immunity, 35, 972, 10.1016/j.immuni.2011.09.019
Newsholme, 1985, Glutamine metabolism in lymphocytes: its biochemical, physiological and clinical importance, Q. J. Exp. Physiol., 70, 473, 10.1113/expphysiol.1985.sp002935
Pearce, 2007, Generation of CD8 T cell memory is regulated by IL-12, J. Immunol., 179, 2074, 10.4049/jimmunol.179.4.2074
Rao, 2012, Transcription factor Foxo1 represses T-bet-mediated effector functions and promotes memory CD8(+) T cell differentiation, Immunity, 36, 374, 10.1016/j.immuni.2012.01.015
Redeker, 2016, Improving Adoptive T Cell Therapy: The Particular Role of T Cell Costimulation, Cytokines, and Post-Transfer Vaccination, Front. Immunol., 7, 345, 10.3389/fimmu.2016.00345
Rodgers, 2005, Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1, Nature, 434, 113, 10.1038/nature03354
Rolf, 2013, AMPKα1: a glucose sensor that controls CD8 T-cell memory, Eur. J. Immunol., 43, 889, 10.1002/eji.201243008
Rosenberg, 2015, Adoptive cell transfer as personalized immunotherapy for human cancer, Science, 348, 62, 10.1126/science.aaa4967
Sásik, 2004, Microarray truths and consequences, J. Mol. Endocrinol., 33, 1, 10.1677/jme.0.0330001
Scharping, 2016, The Tumor Microenvironment Represses T Cell Mitochondrial Biogenesis to Drive Intratumoral T Cell Metabolic Insufficiency and Dysfunction, Immunity, 45, 374, 10.1016/j.immuni.2016.07.009
Shi, 2011, HIF1alpha-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells, J. Exp. Med., 208, 1367, 10.1084/jem.20110278
Staveley-O’Carroll, 2003, In vivo ligation of CD40 enhances priming against the endogenous tumor antigen and promotes CD8+ T cell effector function in SV40 T antigen transgenic mice, J. Immunol., 171, 697, 10.4049/jimmunol.171.2.697
Sukumar, 2013, Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function, J. Clin. Invest., 123, 4479, 10.1172/JCI69589
Terme, 2011, IL-18 induces PD-1-dependent immunosuppression in cancer, Cancer Res., 71, 5393, 10.1158/0008-5472.CAN-11-0993
Tsung, 1997, IL-12 induces T helper 1-directed antitumor response, J. Immunol., 158, 3359, 10.4049/jimmunol.158.7.3359
Tullius, 2014, NAD+ protects against EAE by regulating CD4+ T-cell differentiation, Nat. Commun., 5, 5101, 10.1038/ncomms6101
Tusher, 2001, Significance analysis of microarrays applied to the ionizing radiation response, Proc. Natl. Acad. Sci. USA, 98, 5116, 10.1073/pnas.091062498
van der Windt, 2012, Metabolic switching and fuel choice during T-cell differentiation and memory development, Immunol. Rev., 249, 27, 10.1111/j.1600-065X.2012.01150.x
Wei, 2012, Th17 cells have stem cell-like features and promote long-term immunity, OncoImmunology, 1, 516, 10.4161/onci.19440
Yu, 1999, Glutamine: a precursor of glutathione and its effect on liver, World J. Gastroenterol., 5, 143, 10.3748/wjg.v5.i2.143
Yu, 2013, Adoptive transfer of Tc1 or Tc17 cells elicits antitumor immunity against established melanoma through distinct mechanisms, J. Immunol., 190, 1873, 10.4049/jimmunol.1201989
Zhang, 2010, SIRT1-dependent regulation of chromatin and transcription: linking NAD(+) metabolism and signaling to the control of cellular functions, Biochim. Biophys. Acta, 1804, 1666, 10.1016/j.bbapap.2009.10.022