CD16/PD-L1 bi-specific aptamer for cancer immunotherapy through recruiting NK cells and acting as immunocheckpoint blockade

Molecular Therapy - Nucleic Acids - Tập 27 - Trang 998-1009 - 2022
Aixian Zheng1, Yanlin Du1,2,3, Yiru Wang1,4, Youshi Zheng1, Zhaoyu Ning1,4, Ming Wu1, Cuilin Zhang1, Da Zhang1, Jingfeng Liu1,5, Xiaolong Liu1,5,2
1The United Innovation of Mengchao Hepatobiliary Technology Key Laboratory of Fujian Province, Mengchao Hepatobiliary Hospital of Fujian Medical University, Fuzhou 350025, P.R. China
2Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou 350002, P.R. China
3College of Life Science, Fujian Agriculture and Forestry University, Fuzhou 350002, P.R. China
4College of Biological Science and Engineering, Fuzhou University, Fuzhou 350116, P.R. China
5The Hepatobiliary Medical Center of Fujian Province, Fujian Cancer Hospital & Fujian Medical University Cancer Hospital, Fuzhou 350014, P.R. China

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