CCAAT/enhancer-binding protein β: vai trò của nó trong ung thư vú và liên kết với các receptor tyrosine kinase

10.1016/S0026-0495(03)00311-1

http://2zip.molgen.mpg.de/

http://www.transcriptionfactor.org To predict leucine zippers in your amino acid sequence use:

www.cancer.gov/cancertopics/types/breast The DBD is a database of predicted transcription factors in completely sequenced genomes.

10.1017/S1462399408000641

10.1042/BJ20050009

10.1101/gad.11.17.2153

Raught, 1996, Expression of a translationally regulated, dominant-negative CCAAT/enhancer-binding protein beta isoform and up-regulation of the eukaryotic translation initiation factor 2alpha are correlated with neoplastic transformation of mammary epithelial cells, Cancer Research, 56, 4382

10.1083/jcb.115.4.887

10.1126/science.1092472

10.1038/sj.onc.1209982

10.1074/jbc.M110827200

10.1074/jbc.272.45.28349

10.1016/S1043-2760(97)00114-8

Foekens, 1989, Prognostic value of receptors for insulin-like growth factor 1, somatostatin, and epidermal growth factor in human breast cancer, Cancer Research, 49, 7002

Pekonen, 1988, Receptors for epidermal growth factor and insulin-like growth factor I and their relation to steroid receptors in human breast cancer, Cancer Research, 48, 1343

10.1172/JCI114868

10.1038/nature05887

10.1038/ng2075

10.1038/bjc.1992.256

10.1083/jcb.200107119

10.1016/j.cytogfr.2005.01.001

10.1016/0046-8177(92)90257-4

10.1038/nrc1609

10.1128/MCB.19.10.7181

10.1038/cdd.2008.105

10.1677/erc.0.0100043

Conze, 2001, Autocrine production of interleukin 6 causes multidrug resistance in breast cancer cells, Cancer Research, 61, 8851

10.1101/gad.12.12.1907

Czubayko, 1994, Tumor growth and angiogenesis induced by a secreted binding protein for fibroblast growth factors, Journal of Biological Chemistry, 269, 28243, 10.1016/S0021-9258(18)46920-7

Zahnow, 1997, Overexpression of C/EBPbeta-LIP, a naturally occurring, dominant-negative transcription factor, in human breast cancer, Journal of the National Cancer Institute, 89, 1887, 10.1093/jnci/89.24.1887

10.1016/j.ccr.2004.05.015

10.1038/sj.onc.1209165

10.1038/415530a

10.1073/pnas.0337434100

10.1128/MCB.13.7.3964

10.1074/jbc.M910269199

10.1128/MCB.16.5.2295

10.1074/jbc.M410076200

10.1182/blood-2003-08-2671

10.1074/jbc.M305501200

10.1016/S1097-2765(00)80384-6

10.1074/jbc.M305680200

10.1093/emboj/cdg094

10.1016/j.mce.2008.03.009

10.1074/jbc.273.16.9552

10.1038/364544a0

10.1074/jbc.274.44.31597

10.1073/pnas.90.6.2207

10.1101/gad.6.3.439

10.1126/science.2683088

10.1128/MCB.19.3.1695

10.1073/pnas.90.17.8219

10.1016/0092-8674(91)90531-3

10.1101/gad.1.2.133

10.1016/0092-8674(86)90266-7

10.1042/bj20020508

10.1074/jbc.273.47.30843

10.1016/0092-8674(91)90173-V

10.1101/gad.5.9.1538

10.1093/emboj/16.24.7432

Williams, 1995, CRP2 (C/EBP beta) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificity, EMBO Journal, 14, 3170, 10.1002/j.1460-2075.1995.tb07319.x

10.1128/MCB.16.4.1479

10.1073/pnas.90.20.9606

10.1101/gad.5.10.1754

10.1128/MCB.13.3.1854

Nerlov, 1995, CCAAT/enhancer binding protein-alpha amino acid motifs with dual TBP and TFIIB binding ability co-operate to activate transcription in both yeast and mammalian cells, EMBO Journal, 14, 4318, 10.1002/j.1460-2075.1995.tb00106.x

Mahoney, 1992, Phosphorylation of CCAAT-enhancer binding protein by protein kinase C attenuates site-selective DNA binding, Journal of Biological Chemistry, 267, 19396, 10.1016/S0021-9258(18)41789-9

10.1093/nar/29.14.3087

Burk, 1993, Synergistic activation of the chicken mim-1 gene by v-myb and C/EBP transcription factors, EMBO Journal, 12, 2027, 10.1002/j.1460-2075.1993.tb05852.x

10.1101/gad.2.7.786

10.1126/science.2885917

10.1038/nm1764

10.1101/gad.8.22.2781

10.1186/bcr428

Akira, 1990, A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP family, EMBO Journal, 9, 1897, 10.1002/j.1460-2075.1990.tb08316.x

10.1128/MCB.23.8.2720-2732.2003

10.1016/0092-8674(88)90220-6

10.1242/jcs.02459

10.1128/MCB.17.11.6609

10.1091/mbc.e08-03-0329

Alaoui-Jamali, 2003, Regulation of multiple tumor microenvironment markers by overexpression of single or paired combinations of ErbB receptors, Cancer Research, 63, 3764

10.1128/MCB.24.17.7380-7391.2004

10.1158/1055-9965.EPI-07-0654

10.1074/jbc.M007576200

10.1074/jbc.272.48.30356

10.1371/journal.pbio.0060108

10.1074/jbc.271.7.3891

10.1172/JCI3135

10.1073/pnas.90.21.10193

10.1093/nar/23.21.4371

10.1074/jbc.M107527200

10.1677/ERC-07-0080

10.1038/onc.2008.226

10.1172/JCI117266

10.4049/jimmunol.176.8.4843

10.1002/jcp.1139

10.1126/science.2530632

10.1023/A:1023929504884

Zhou, 2001, Malignant breast epithelial cells stimulate aromatase expression via promoter II in human adipose fibroblasts: an epithelial-stromal interaction in breast tumors mediated by CCAAT/enhancer binding protein beta, Cancer Research, 61, 2328

10.1039/b801920g

10.1023/A:1006194700667

10.1158/0008-5472.CAN-07-0200

10.1042/bj20030140

10.1038/cgt.2008.73

10.1016/S0092-8674(02)00966-2

Christian, 2002, Functional association of PR and CCAAT/enhancer-binding protein beta isoforms: promoter-dependent cooperation between PR-B and liver-enriched inhibitory protein, or liver-enriched activatory protein and PR-A in human endometrial stromal cells, Molecular Endocrinology, 16, 141

10.1074/jbc.274.15.10609

Holdaway, 1977, Hormone binding by human mammary carcinoma, Cancer Research, 37, 1946

10.1172/JCI4243

10.1074/jbc.M204873200

Bonneterre, 1990, Prognostic significance of insulin-like growth factor 1 receptors in human breast cancer, Cancer Research, 50, 6931

10.1038/nature06546

10.1016/S1476-5586(04)80047-2

10.1016/S0076-6879(03)76012-1

10.1210/me.2002-0239

10.1046/j.1365-2613.1998.00082.x

Screpanti, 1995, Lymphoproliferative disorder and imbalanced T-helper response in C/EBP beta-deficient mice, EMBO Journal, 14, 1932, 10.1002/j.1460-2075.1995.tb07185.x

10.1016/0092-8674(95)90418-2

10.1128/MCB.25.5.1971-1979.2005

10.1074/jbc.M801178200

10.1073/pnas.0607378104

10.1074/jbc.273.45.29279

10.1073/pnas.0503891102

10.1038/sj.bjc.6600213

10.1101/gad.7.5.749

10.1128/MCB.16.8.4257

10.1074/jbc.M801046200

10.1681/ASN.2007040406

10.1128/MCB.10.6.2757

Kagan, 2003, Complex regulation of the fibroblast growth factor-binding protein in MDA- MB-468 breast cancer cells by CCAAT/enhancer-binding protein beta, Cancer Research, 63, 1696

10.1074/jbc.270.2.647

10.1128/MCB.24.9.3682-3691.2004

10.1186/bcr53

10.1016/j.ab.2005.02.012

10.1016/j.tcb.2007.07.004

10.1073/pnas.94.12.6462

Calkhoven, 2000, Translational control of C/EBPalpha and C/EBPbeta isoform expression, Genes and Development, 14, 1920, 10.1101/gad.14.15.1920

10.1002/ijc.21812

10.1002/ijc.2910610205

10.1023/A:1025900908026

10.1016/S1097-2765(00)80237-3

10.2337/db06-0310

Ratajczak, 1992, Multiple elements within the glucocorticoid regulatory unit of the rat alpha 1-acid glycoprotein gene are recognition sites for C/EBP, Journal of Biological Chemistry, 267, 11111, 10.1016/S0021-9258(19)49882-7

10.1073/pnas.012437299

10.1023/A:1009523501499

10.1210/endo.141.1.7237

10.2337/diab.44.3.267

10.1016/j.cell.2008.03.038

10.1016/j.cell.2008.03.039

10.1074/jbc.273.24.14796

10.1038/sj.bjc.6604098

10.4049/jimmunol.179.8.5378

10.1080/07853890600551037

10.1158/1078-0432.CCR-06-1164

10.1101/gad.4.9.1541

10.1634/stemcells.19-2-125

10.1038/sj.onc.1206216

10.1073/pnas.0702507104

10.1146/annurev.cellbio.16.1.591

Zahnow, 2001, A role for CCAAT/enhancer binding protein beta-liver-enriched inhibitory protein in mammary epithelial cell proliferation, Cancer Research, 61, 261

10.1128/MCB.24.8.3238-3250.2004

10.1016/S0145-2126(01)00150-3

10.1093/nar/30.5.1240

10.1074/jbc.271.11.6217

10.1016/j.bone.2006.01.164

10.1074/jbc.M000764200

Minucci, 2006, Histone deacetylase inhibitors and the promise of epigenetic (and more) treatments for cancer. Nature Reviews, Cancer, 6, 38

10.1074/jbc.M802132200

10.4161/cc.5.9.2733

10.1073/pnas.062036999

Nolten, 1994, Expression of the insulin-like growth factor I gene is stimulated by the liver-enriched transcription factors C/EBP alpha and LAP, Molecular Endocrinology, 8, 1636

10.1074/jbc.M008542200

10.1074/jbc.M206266200

10.1016/j.ccr.2006.07.019

10.1200/JCO.2002.20.1.42

10.1128/MCB.22.18.6321-6335.2002

Buck, 1994, LAP (NF-IL-6), a tissue-specific transcriptional activator, is an inhibitor of hepatoma cell proliferation, EMBO Journal, 13, 851, 10.1002/j.1460-2075.1994.tb06328.x

Milazzo, 1992, Insulin receptor expression and function in human breast cancer cell lines, Cancer Research, 52, 3924

10.1016/S1097-2765(01)00374-4

10.1016/S1097-2765(03)00521-5

10.1074/jbc.M203913200

10.1038/sj.onc.1207816

10.1016/0092-8674(90)90459-R

10.1056/NEJMoa021967

10.1038/sj.emboj.7600789

10.1038/onc.2008.245

10.1101/gad.12.12.1917

10.1128/MCB.11.10.4959

10.1002/gcc.20368

10.1074/jbc.274.7.4147

Gruvberger, 2001, Estrogen receptor status in breast cancer is associated with remarkably distinct gene expression patterns, Cancer Research, 61, 5979

10.1038/labinvest.3700166

10.1074/jbc.M010193200

10.1017/S146239940600010X

Seagroves, 2000, C/EBPbeta (CCAAT/enhancer binding protein) controls cell fate determination during mammary gland development, Molecular Endocrinology, 14, 359

10.1128/MCB.10.12.6642

Combates, 1994, NF-IL6, a member of the C/EBP family of transcription factors, binds and trans-activates the human MDR1 gene promoter, Journal of Biological Chemistry, 269, 29715, 10.1016/S0021-9258(18)43939-7

10.1038/sj.onc.1209797

10.1126/science.256.5055.370

10.1073/pnas.0407617101

10.1172/JCI2401

10.1124/mol.65.4.906

10.1042/BJ20071649

10.1074/jbc.M511451200