CAR T-cell treatment during the COVID-19 pandemic: Management strategies and challenges

Current Research in Translational Medicine - Tập 68 - Trang 111-118 - 2020
Yongxian Hu1,2,3, Elaine Tan Su Yin1,2,3, Yingying Yang1,2,3, Hengwei Wu1,2,3, Guoqing Wei1,2,3, Junwei Su4, Qu Cui5, Aiyun Jin1,2,3, Li Yang1,2,3, Shan Fu1,2,3, Jianfeng Zhou6, Lugui Qiu7, Xi Zhang8, Aibin Liang9, Hongmei Jing10, Yuhua Li11, Didier Blaise12, Mohamad Mohty13,14, Arnon Nagler15, He Huang1,2,3
1Bone Marrow Transplantation Center, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
2Zhejiang Province Engineering Laboratory for Stem Cell and Immunity Therapy, Hangzhou, China
3Institute of Hematology, Zhejiang University, Hangzhou, China
4State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Department of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China
5Department of Hematology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
6Department of Hematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
7State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China
8Medical Center of Hematology, Xinqiao Hospital, Army Medical University, Chongqing, China
9Department of Hematology, Shanghai Tongji Hospital, Shanghai, China
10Department of Hematology, Peking University Third Hospital, Beijing, China
11Department of Hematology, ZhuJiang Hospital of Southern Medical University, Guangzhou, China
12Transplant and Cellular Immunotherapy Programs, Department of Hematology, Institut Paoli-Calmettes, Aix Marseille Univ, CNRS, INSERM, CRCM, Marseille, France
13Sorbonne University, Department of Hematology, Hôpital Saint Antoine, Paris, France
14INSERM UMRs 938, EBMT Paris Study Office/CEREST-TC, Paris, France
15Hematology and Bone Marrow Transplantation Division, Chaim Sheba Medical Center, Tel-Hashomer, Israel

Tài liệu tham khảo

World Health Organization, 2020 Singh, 2020, CAR T cells: continuation in a revolution of immunotherapy, Lancet Oncol, 21, e168, 10.1016/S1470-2045(19)30823-X Elsallab, 2020, CAR T-cell product performance in haematological malignancies before and after marketing authorisation, Lancet Oncol, 21, e104, 10.1016/S1470-2045(19)30729-6 Available from: https://www.ebmt.org/sites/default/files/2020-04/EBMT-COVID-19-guidelines_v.6.1%282020-04-07%29.pdf. Available from: https://www.astct.org/viewdocument/astct-interim-patient-guidelines-ap?CommunityKey=d3949d84-3440-45f4-814290ea05adb0e5&tab=librarydocuments. Wang, 2020, Clinical diagnosis of 8274 samples with 2019 novel coronavirus in Wuhan, medRxiv Hong, 2020, Recommendations for prophylaxis and prevention of COVID-19 in hematology department, Zhonghua Xue Ye Xue Za Zhi Bi, 2020, Epidemiology and transmission of COVID-19 in Shenzhen China: analysis of 391 cases and 1,286 of their close contacts, MedRxiv Chang, 2020, Coronavirus disease 2019: coronaviruses and blood safety, Transfus Med Rev, 10.1016/j.tmrv.2020.02.003 Zhang, 2020, A promising anti-cytokine-storm targeted therapy for COVID-19: the artificial-liver blood-purification system, Engineering (Beijing) Li, 2020, Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2), Science, 10.1126/science.abb3221 Liu, 2019, Engineering switchable and programmable universal CARs for CAR T therapy, J Hematol Oncol, 12, 69, 10.1186/s13045-019-0763-0 Chen, 2020, COVID-19 with post-chemotherapy agranulocytosis in childhood acute leukemia: a case report, Zhonghua Xue Ye Xue Za Zhi, 41, E004 Ozma, 2020, Clinical manifestation, diagnosis, prevention and control of SARS-CoV-2 (COVID-19) during the outbreak period, Infez Med, 28, 153 Liu, 2018, Cytokine release syndrome: grading, modeling, and new therapy, J Hematol Oncol, 11, 121, 10.1186/s13045-018-0653-x Yakoub-Agha, 2020, Management of adults and children undergoing chimeric antigen receptor T-cell therapy: best practice recommendations of the European Society for Blood and Marrow Transplantation (EBMT) and the Joint Accreditation Committee of ISCT and EBMT (JACIE), Haematologica, 105, 297, 10.3324/haematol.2019.229781 Mohty, 2019, CD19 chimeric antigen receptor-T cells in B-cell leukemia and lymphoma: current status and perspectives, Leukemia, 33, 2767, 10.1038/s41375-019-0615-5 Hay, 2017, Kinetics and biomarkers of severe cytokine release syndrome after CD19 chimeric antigen receptor-modified T-cell therapy, Blood, 130, 2295, 10.1182/blood-2017-06-793141 Teachey, 2016, Identification of predictive biomarkers for cytokine release syndrome after chimeric antigen receptor T-cell therapy for acute lymphoblastic leukemia, Cancer Discov, 6, 664, 10.1158/2159-8290.CD-16-0040 Zhang, 2020, The cytokine release syndrome (CRS) of severe COVID-19 and Interleukin-6 receptor (IL-6R) antagonist Tocilizumab may be the key to reduce the mortality, Int J Antimicrob Agents, 10.1016/j.ijantimicag.2020.105954 Huang, 2020, Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China, Lancet, 395, 497, 10.1016/S0140-6736(20)30183-5 Ruan, 2020, Clinical predictors of mortality due to COVID-19 based on an analysis of data of 150 patients from Wuhan, China, Intensive Care Med, 1 Xu, 2020, Management of corona virus disease-19 (COVID-19): the Zhejiang experience, Zhejiang Da Xue Xue Bao Yi Xue Ban, 49 Zhang, 2020, First case of COVID-19 in a patient with multiple myeloma successfully treated with tocilizumab, Blood Adv, 4, 1307, 10.1182/bloodadvances.2020001907 Portnoy, 2020, Telemedicine in the era of COVID-19, J Allergy Clin Immunol Pract, 10.1016/j.jaip.2020.03.008 Kansagra, 2019, Bone Marrow Transplant, 54, 1868, 10.1038/s41409-019-0451-2 Caruso, 2018, Steering CAR T cells to distinguish friend from foe, Oncoimmunology, 8, 10.1080/2162402X.2016.1271857 Jin, 2020, COVID-19 in a patient with chronic lymphocytic leukaemia, Lancet Haematol, 7, e351, 10.1016/S2352-3026(20)30074-0