Burden of anemia and its underlying causes in 204 countries and territories, 1990–2019: results from the Global Burden of Disease Study 2019

Springer Science and Business Media LLC - Tập 14 - Trang 1-16 - 2021
Saeid Safiri1,2, Ali-Asghar Kolahi3, Maryam Noori4, Seyed Aria Nejadghaderi5,6, Nahid Karamzad7, Nicola Luigi Bragazzi8, Mark J. M. Sullman9,10, Morteza Abdollahi3, Gary S. Collins11,12, Jay S. Kaufman13, Jessica A. Grieger14,15
1Research Center for Integrative Medicine in Aging, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran
2Social Determinants of Health Research Center, Department of Community Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
3Social Determinants of Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran
4Student Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
5School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
6Systematic Review and Meta-analysis Expert Group (SRMEG), Universal Scientific Education and Research Network (USERN), Tehran, Iran
7Nutrition Research Center, Department of Biochemistry and Diet Therapy, School of Nutrition and Food Sciences, Tabriz University of Medical Sciences, Tabriz, Iran
8Centre for Disease Modelling, York University, Toronto, Canada
9Department of Life and Health Sciences, University of Nicosia, Nicosia, Cyprus
10Department of Social Sciences, University of Nicosia, Nicosia, Cyprus
11Centre for Statistics in Medicine, NDORMS, Botnar Research Centre, University of Oxford, Oxford, UK
12NIHR Oxford Biomedical Research Centre, Oxford University Hospitals NHS Foundation Trust, Oxford, UK
13Department of Epidemiology, Biostatistics and Occupational Health, Faculty of Medicine, McGill University, Montreal, Canada
14Adelaide Medical School, University of Adelaide, Adelaide, Australia
15Robinson Research Institute, University of Adelaide, Adelaide, SA, Australia

Tóm tắt

Anemia is a common disease which affects around 40% of children and 30% of reproductive age women and can have major health consequences. The present study reports the global, regional and national burden of anemia and its underlying causes between 1990 and 2019, by age, sex and socio-demographic index (SDI). Publicly available data on the point prevalence and years lived with disability (YLDs) were retrieved from the global burden of disease (GBD) 2019 study for 204 countries and territories between 1990 and 2019. The point prevalence, YLD counts and rates per 100,000 population were presented, along with their corresponding 95% uncertainty intervals. In 2019, the global age-standardized point prevalence and YLD rates for anemia were 23,176.2 (22,943.5–23,418.6) and 672.4 (447.2–981.5) per 100,000 population, respectively. Moreover, the global age-standardized point prevalence and YLD rate decreased by 13.4% (12.1–14.5%) and 18.8% (16.9–20.8%), respectively, over the period 1990–2019. The highest national point prevalences of anemia were found in Zambia [49327.1 (95% UI: 46,838.5–51,700.1)], Mali [46890.1 (95% UI: 44,301.1–49,389.8)], and Burkina Faso [46117.2 (95% UI: 43,640.7–48,319.2)]. In 2019, the global point prevalence of anemia was highest in the 15–19 and 95+ age groups in females and males, respectively. Also, the burden of anemia was lower in regions with higher socio-economic development. Globally, most of the prevalent cases were attributable to dietary iron deficiency, as well as hemoglobinopathies and hemolytic anemias. Anemia remains a major health problem, especially among females in less developed countries. The implementation of preventive programs with a focus on improving access to iron supplements, early diagnosis and the treatment of hemoglobinopathies should be taken into consideration.

Tài liệu tham khảo

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