Bronchopulmonary dysplasia - an overview about pathophysiologic concepts

Doyle LW: Evaluation of neonatal intensive care for extremely-low-birth-weight infants. Semin Fetal Neonatal Med 2006, 11: 139–145. 10.1016/j.siny.2005.11.009

Stoll BJ, Hansen NI, Bell EF, Shankaran S, Laptook AR, Walsh MC, Hale EC, Newman NS, Schibler K, Carlo WA, Kennedy KA, Poindexter BB, Finer NN, Ehrenkranz RA, Duara S, Sanchez PJ, O'Shea TM, Goldberg RN, Van Meurs KP, Faix RG, Phelps DL, Frantz ID, 3rd, Watterberg KL, Saha S, Das A, Higgins RD (2010) Neonatal outcomes of extremely preterm infants from the NICHD Neonatal Research Network. Pediatrics 126:443–456

Gortner L, Misselwitz B, Milligan D, Zeitlin J, Kollee L, Boerch K, Agostino R, Van Reempts P, Chabernaud JL, Breart G, Papiernik E, Jarreau PH, Carrapato M, Gadzinowski J, Draper E (2011) Rates of bronchopulmonary dysplasia in very preterm neonates in Europe: results from the MOSAIC cohort. Neonatology 99:112–117

Carraro S, Filippone M, Da Dalt L, Ferraro V, Maretti M, Bressan S, El Mazloum D, Baraldi E (2013) Bronchopulmonary dysplasia: the earliest and perhaps the longest lasting obstructive lung disease in humans. Early Hum Dev 89(Suppl 3):S3–S5

Jobe AH, Ikegami M: Prevention of bronchopulmonary dysplasia. Curr Opin Pediatr 2001, 13: 124–129. 10.1097/00008480-200104000-00006

Bhandari A, Panitch HB: Pulmonary outcomes in bronchopulmonary dysplasia. Semin Perinatol 2006, 30: 219–226. 10.1053/j.semperi.2006.05.009

Coalson JJ: Pathology of bronchopulmonary dysplasia. Semin Perinatol 2006, 30: 179–184. 10.1053/j.semperi.2006.05.004

Coalson JJ: Pathology of new bronchopulmonary dysplasia. Semin neonatol 2003, 8: 73–81. 10.1016/S1084-2756(02)00193-8

Jobe AH: The new bronchopulmonary dysplasia. Curr Opin Pediatr 2011, 23: 167–172. 10.1097/MOP.0b013e3283423e6b

Bose CL, Dammann CE, Laughon MM: Bronchopulmonary dysplasia and inflammatory biomarkers in the premature neonate. Arch Dis Child Fetal Neonatal Ed 2008, 93: F455-F461. 10.1136/adc.2007.121327

Bhandari V: Hyperoxia-derived lung damage in preterm infants. Semin Fetal Neonatal Med 2010, 15: 223–229. 10.1016/j.siny.2010.03.009

Wallace MJ, Probyn ME, Zahra VA, Crossley K, Cole TJ, Davis PG, Morley CJ, Hooper SB (2009) Early biomarkers and potential mediators of ventilation-induced lung injury in very preterm lambs. Respir Res 10:19

Gortner L, Shen J, Tutdibi E: Sexual dimorphism of neonatal lung development. Klin Padiatr 2013, 225: 64–69. 10.1055/s-0033-1333758

Blackwell TS, Hipps AN, Yamamoto Y, Han W, Barham WJ, Ostrowski MC, Yull FE, Prince LS (2011) NF-kappaB signaling in fetal lung macrophages disrupts airway morphogenesis. J Immunol 187:2740–2747

Bland RD, Ertsey R, Mokres LM, Xu L, Jacobson BE, Jiang S, Alvira CM, Rabinovitch M, Shinwell ES, Dixit A (2008) Mechanical ventilation uncouples synthesis and assembly of elastin and increases apoptosis in lungs of newborn mice. Prelude to defective alveolar septation during lung development? Am J Physiol Lung Cell Mol Physiol 294:L3–L14

Iosef C, Alastalo TP, Hou Y, Chen C, Adams ES, Lyu SC, Cornfield DN, Alvira CM (2012) Inhibiting NF-kappaB in the developing lung disrupts angiogenesis and alveolarization. Am J Physiol Lung Cell Mol Physiol 302:L1023–L1036

Thebaud B, Abman SH: Bronchopulmonary dysplasia: where have all the vessels gone? Roles of angiogenic growth factors in chronic lung disease. Am J Respir Crit Care Med 2007, 175: 978–985. 10.1164/rccm.200611-1660PP

Bourbon J, Boucherat O, Chailley-Heu B, Delacourt C: Control mechanisms of lung alveolar development and their disorders in bronchopulmonary dysplasia. Pediatr Res 2005, 57: 38r-46r. 10.1203/01.PDR.0000159630.35883.BE

Teichert-Kuliszewska K, Kutryk MJ, Kuliszewski MA, Karoubi G, Courtman DW, Zucco L, Granton J, Stewart DJ (2006) Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension. Circ Res 98:209–217

Maeda Y, Dave V, Whitsett JA: Transcriptional control of lung morphogenesis. Physiol Rev 2007, 87: 219–244. 10.1152/physrev.00028.2006

Hilgendorff A, Reiss I, Ehrhardt H, Eickelberg O, Alvira CM: Chronic lung disease in the preterm infant. Lessons learned from animal models. Am J Respir Cell Mol Biol 2014, 50: 233–245.

Hines EA, Sun X: Tissue crosstalk in lung development. J Cell Biochem 2014, 115: 1469–1477. 10.1002/jcb.24811

Asikainen TM, Chang LY, Coalson JJ, Schneider BK, Waleh NS, Ikegami M, Shannon JM, Winter VT, Grubb P, Clyman RI, Yoder BA, Crapo JD, White CW (2006) Improved lung growth and function through hypoxia-inducible factor in primate chronic lung disease of prematurity. FASEB J 20:1698–1700

Compernolle V, Brusselmans K, Acker T, Hoet P, Tjwa M, Beck H, Plaisance S, Dor Y, Keshet E, Lupu F, Nemery B, Dewerchin M, Van Veldhoven P, Plate K, Moons L, Collen D, Carmeliet P (2002) Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice. Nat Med 8:702–710

Suzuki Y, Montagne K, Nishihara A, Watabe T, Miyazono K: BMPs promote proliferation and migration of endothelial cells via stimulation of VEGF-A/VEGFR2 and angiopoietin-1/Tie2 signalling. J Biochem 2008, 143: 199–206. 10.1093/jb/mvm215

de Jesus Perez VA, Alastalo TP, Wu JC, Axelrod JD, Cooke JP, Amieva M, Rabinovitch M (2009) Bone morphogenetic protein 2 induces pulmonary angiogenesis via Wnt-beta-catenin and Wnt-RhoA-Rac1 pathways. J Cell Biol 184:83–99

Alvira CM, Abate A, Yang G, Dennery PA, Rabinovitch M (2007) Nuclear factor-kappaB activation in neonatal mouse lung protects against lipopolysaccharide-induced inflammation. Am J Respir Crit Care Med 175:805–815

Bland RD, Mokres LM, Ertsey R, Jacobson BE, Jiang S, Rabinovitch M, Xu L, Shinwell ES, Zhang F, Beasley MA (2007) Mechanical ventilation with 40% oxygen reduces pulmonary expression of genes that regulate lung development and impairs alveolar septation in newborn mice. Am J Physiol Lung Cell Mol Physiol 293:L1099–L1110

Copland IB, Kavanagh BP, Engelberts D, McKerlie C, Belik J, Post M: Early changes in lung gene expression due to high tidal volume. Am J Respir Crit Care Med 2003, 168: 1051–1059. 10.1164/rccm.200208-964OC

Coalson JJ, Kuehl TJ, Escobedo MB, Hilliard JL, Smith F, Meredith K, Null DM Jr., Walsh W, Johnson D, Robotham JL (1982) A baboon model of bronchopulmonary dysplasia II pathologic features. Exp Mol Pathol 37:335–350

Escobedo MB, Hilliard JL, Smith F, Meredith K, Walsh W, Johnson D, Coalson JJ, Kuehl TJ, Null DM Jr., Robotham JL (1982) A baboon model of bronchopulmonary dysplasia I clinical features. Exp mol Pathol 37:323–334

Bonvillain RW, Danchuk S, Sullivan DE, Betancourt AM, Semon JA, Eagle ME, Mayeux JP, Gregory AN, Wang G, Townley IK, Borg ZD, Weiss DJ, Bunnell BA (2012) A nonhuman primate model of lung regeneration: detergent-mediated decellularization and initial in vitro recellularization with mesenchymal stem cells. Tissue Eng Part A 18:2437–2452