Broad-spectrum activity of 8-chloro-7-deazaguanosine against RNA virus infections in mice and rats

Antiviral Research - Tập 26 - Trang 203-209 - 1995
Donald F. Smee1, Hassan A. Alaghamandan1, Kandasamy Ramasamy1, Ganapathi R. Revankar1
1ICN Nucleic Acid Research Institute, Costa Mesa, CA 92626, USA

Tài liệu tham khảo

Kunder, 1993, Biological response modifier-mediated resistance to herpesvirus infections requires induction of αβ interferon, Antiviral Res., 21, 129, 10.1016/0166-3542(93)90049-O Michael, 1993, Alkylpurines as immunepotentiating agents, J. Med. Chem., 36, 3431, 10.1021/jm00074a025 Morahan, 1991, Varying role of αβ interferon in the antiviral efficacy of synthetic immuno-modulators against Semliki Forest virus infection, Antiviral Res., 15, 241, 10.1016/0166-3542(91)90070-8 Nagahara, 1990, Thiazolo[4,5-d]pyrimidine nucleosides, J. Med. Chem., 33, 407, 10.1021/jm00163a064 Ramasamy, 1988, A facile and improved synthesis of tubercidin and certain pyrrolo[2,3-d]pyrimidine nucleosides by the stereospecific sodium salt glycosylation procedure, J. Heterocycl. Chem., 25, 1893, 10.1002/jhet.5570250652 Sarzotti, 1989, The in vivo antiviral effect of CL246,738 is mediated by the independent induction of interferon-α and interferon-β, J. Interferon Res., 9, 265, 10.1089/jir.1989.9.265 Smee, 1989, Broad-spectrum in vivo antiviral activity of 7-thia-8-oxoguanosine, a novel immunopotentiating agent, Antimicrob. Agents Chemother., 33, 1487, 10.1128/AAC.33.9.1487 Smee, 1990, Antiviral activity of the novel immune modulator 7-thia-8-oxoguanosine, J. Biol. Response Modif., 9, 24 Smee, 1990, Intranasal treatment of picornavirus and coronavirus respiratory infections in rodents using 7-thia-8-oxoguanosine, Antiviral Chem. Chemother., 1, 47, 10.1177/095632029000100108 Smee, 1990, Roles of interferon and natural killer cells in the antiviral activity of 7-thia-8-oxoguanosine against Semliki Forest virus infections in mice, Antiviral Res., 13, 91, 10.1016/0166-3542(90)90025-3 Smee, 1991, Immunoenhancing properties and antiviral activity of 7-deazaguanosine in mice, Antimicrob. Agents Chemother., 35, 152, 10.1128/AAC.35.1.152 Smee, 1991, Prophylactic and therapeutic activities of 7-thia-8-oxoguanosine against Punta Toro virus infections in mice, Antiviral Res., 15, 229, 10.1016/0166-3542(91)90069-4 Smee, 1992, Antiviral and immunoenhancing properties of 7-thia-8-oxoguanosine and related guanosine analogues, Can. J. Infect. Dis., 3, 41B, 10.1155/1992/382672 Stringfellow, 1977, Suppressed response to interferon induction in mice infected with encephalomyocarditis virus, Semliki Forest virus, influenza A2 virus, Herpesvirus hominis type 2, or murnie cytomegalovirus, J. Infect. Dis., 135, 540, 10.1093/infdis/135.4.540