Branched synthetic peptide constructs mimic cellular binding and efflux of apolipoprotein AI in reconstituted high density lipoproteins

Forte, 1994, The role of apolipoprotein A-I-containing lipoproteins in atherosclerosis, Curr Opin Lipidol, 5, 354, 10.1097/00041433-199410000-00007 Rubin, 1991, Inhibition of early atherogenesis in transgenic mice by human apolipoprotein A-I, Nature, 353, 265, 10.1038/353265a0 Breslow, 1996, New mouse models of lipoprotein disorders and atherosclerosis, 363 Mahlberg, 1992, Cellular cholesterol efflux: role of cell membrane kinetic pools and interaction with apolipoproteins AI, AII, and Cs, J Biol Chem, 267, 4541, 10.1016/S0021-9258(18)42867-0 Luchoomun, 1994, Structural domain of apolipoprotein A-I involved in its interaction with cells, Biochim Biophys Acta, 1212, 319, 10.1016/0005-2760(94)90206-2 Banka, 1994, Localization of an apolipoprotein A-I epitope critical for lipoprotein-mediated cholesterol efflux from monocytic cells, J Biol Chem, 269, 10 288, 10.1016/S0021-9258(17)34059-0 Fielding, 1994, Unique epitope of apolipoprotein A-I expressed in pre-β-1 high-density lipoprotein and its role in the catalyzed efflux of cellular cholesterol, Biochemistry, 33, 6981, 10.1021/bi00188a030 Palgunachari, 1996, Only the two end helices of eight tandem amphipathic helical domains of human apo A-I have significant lipid affinity. Implications for HDL assembly, Arterioscler Thromb Vasc Biol, 161, 328, 10.1161/01.ATV.16.2.328 Fielding, 1972, A protein cofactor of lecithin: cholesterol acyl transferase, Biochim Biophys Res Commun, 46, 1493, 10.1016/0006-291X(72)90776-0 Jonas, 1987, Reaction of discoidal complexes of apolipoprotein A-I and various phosphatidylcholines with lecithin cholesterol acyltransferase, J Biol Chem, 262, 4818, 10.1016/S0021-9258(18)61297-9 Pieters, 1993, Cholesterol esters selectively delivered in vivo by high-density-lipoprotein subclass Lp-AI to rat liver are processed faster into bile acids than are LpA-I/LpA-II-derived cholesteryl esters, Biochem J, 292, 819, 10.1042/bj2920819 Acton, 1996, Identification of scavenger receptor SR-BI as a high density lipoprotein receptor, Science, 271, 518, 10.1126/science.271.5248.518 Brasseur, 1990, Mode of assembly of amphipathic helical segments in model high density lipoproteins, Biochim Biophys Acta, 1043, 245, 10.1016/0005-2760(90)90023-Q Pownall, 1987, Lipid-protein interactions and lipoprotein reassembly, 95 Yokoyama, 1980, The mechanism of activation of lecithin:cholesterol acyl transferase by apolipoprotein A-I and an amphiphilic peptide, J Biol Chem, 255, 7333, 10.1016/S0021-9258(20)79708-5 Fukushima, 1980, Chain length-function correlation of amphiphilic peptides: synthesis and surface properties of a tetratetracontapeptide segment of apolipoprotein A-I, J Biol Chem, 255, 10 651, 10.1016/S0021-9258(19)70356-1 Vanloo, 1995, Association of synthetic peptide fragments of human apolipoprotein A-I with phospholipids, J Lipid Res, 36, 1686, 10.1016/S0022-2275(20)41488-9 Demoor, 1996, Branched synthetic constructs that mimic the physico-chemical properties of apolipoprotein AI in reconstituted high-density lipoproteins, Eur J Biochem, 239, 74, 10.1111/j.1432-1033.1996.0074u.x Brasseur, 1991, Molecular modeling of the amphipathic helices of the plasma apolipoproteins, Proteins Struct Funct Genet, 13, 246, 10.1002/prot.340130307 Mezdour, 1987, Anion-exchange fast protein liquid chromatographic characterisation and purification of apolipoproteins A-I, A-II, C-I, C-II, C-III0, C-III1, C-III2 and E from human plasma, J Chromatogr, 414, 35, 10.1016/0378-4347(87)80022-1 Bonomo, 1988, A rapid method for the synthesis of protein–lipid complexes using adsorption chromatography, J Lipid Res, 29, 380, 10.1016/S0022-2275(20)38530-8 Lowry, 1951, Protein measurement with the Folin phenol reagent, J Biol Chem, 193, 265, 10.1016/S0021-9258(19)52451-6 Bilheimer, 1972, The metabolism of low density lipoproteins. Preliminary in vitro and in vivo observations, Biochim Biophys Acta, 260, 212, 10.1016/0005-2760(72)90034-3 Marcel, 1991, The epitopes of apolipoprotein A-I define distinct structural domains including a mobile middle region, J Biol Chem, 266, 3644, 10.1016/S0021-9258(19)67843-9 Calabresi, 1993, Apolipoprotein A-I conformation in discoidal particles: evidence for alternate structures, Biochemistry, 32, 6477, 10.1021/bi00076a023 McConahey, 1980, Radioiodination of proteins by the use of the chloramine T method, Methods Enzymol, 70, 210, 10.1016/S0076-6879(80)70050-2 De La Llera Moya, 1994, A cell culture system for screening human serum for ability to promote cellular cholesterol efflux: relationships between serum components and efflux, esterification and transfer, Arterioscler Thromb, 14, 1056, 10.1161/01.ATV.14.7.1056 Vercaemst, 1989, Separation and quantitation of free cholesterol and cholesteryl esters in a macrophage cell line by high performance liquid chromatography, J Chromatogr, 494, 43, 10.1016/S0378-4347(00)82655-9 Peelman, 1998, A proposed architecture for lecithin cholesterol acyl transferase. Identification of the catalytic triad and molecular modeling of LCAT, Prot Sci, 7, 587, 10.1002/pro.5560070307 Vanloo, 1992, Activation of lecithin cholesterol acyl transferase (LCAT) by the CNBr fragments of human apo AI and conversion of the discoidal complexes into spherical particles, Biochim Biophys Acta, 1128, 258, 10.1016/0005-2760(92)90316-N Phillips, 1980, Mechanism of cholesterol efflux from cells, Atherosclerosis, 36, 409, 10.1016/0021-9150(80)90220-8 Lagrost, 1995, Modulation of cholesterol efflux from Fu5AH hepatoma cells by the apolipoprotein content of high density lipoprotei particles, J Biol Chem, 270, 13 004, 10.1074/jbc.270.22.13004 Davidson, 1995, Effects of acceptor particle size on the efflux of cellular free cholesterol, J Biol Chem, 270, 17 106, 10.1074/jbc.270.29.17106 Von Eckeardstein, 1993, Interaction of reconstituted high density lipoproteins discs containing apoA-I variants with murine adipocytes and macrophages: evidence for reduced cholesterol efflux promotion by apo A-I (Pro165→Arg), J Biol Chem, 268, 2616, 10.1016/S0021-9258(18)53819-9 Allan, 1992, Antibodies to the carboxyl terminus of human apolipoprotein AI, J Biol Chem, 267, 13 257, 10.1016/S0021-9258(18)42203-X Allan, 1993, Monoclonal antibodies to human apolipoprotein AI: probing the putative receptor binding domain of apolipoprotein AI, Biochem J, 290, 449, 10.1042/bj2900449 Barter, 1985, Lipoprotein substrates for plasma cholesterol esterification. Influence of particle size and composition of the high density lipoprotein subfraction 3, Atherosclerosis, 58, 97, 10.1016/0021-9150(85)90058-9 Hoelvoet, 1995, Phospholipid binding and lecithin:cholesterol acyltransferase activation properties of apolipoprotein A-I mutants, Biochemistry, 34, 13 334, 10.1021/bi00041a009