Both activators and inhibitors of protein kinase C promote the inhibition of phenylephrine-induced [Ca2+]i oscillations in single intact rat hepatocytes

Berridge, 1990, Calcium oscillations, J. Biol. Chem., 265, 9583, 10.1016/S0021-9258(19)38704-6 Woods, 1986, Repetitive transient rises in cytoplasmic free calcium in hormonestimulated hepatocytes, Nature, 319, 600, 10.1038/319600a0 Woods, 1987, Agonistinduced oscillations in cytoplasmic free calcium concentration in single rat hepatocytes, Cell Calcium, 8, 79, 10.1016/0143-4160(87)90038-8 Berridge, 1993, Inositol trisphosphate and calcium signalling, Nature, 361, 315, 10.1038/361315a0 Sanchez-Bueno, 1990, Inhibitors of protein kinase C prolong the falling phase of each free-calcium transient in a hormone-stimulated hepatocyte, Biochem. J., 268, 627, 10.1042/bj2680627 Berridge, 1988, Spatial and temporal aspects of cell signalling, Philos. Trans. R. Soc. Lond. [Biol], 320, 325, 10.1098/rstb.1988.0080 Cobbold, 1988, The generation of repetitive free calcium transients in a hormonestimulated hepatocyte, 135 Cobbold, 1990, Receptor control of calcium transients, 185 Woods, 1987, Phorbolester-induced alterations of free calcium ion transients in single rat hepatocytes, Biochem. J., 246, 619, 10.1042/bj2460619 Sanchez-Bueno, 1992, Effect of perturbing diacylglycerol metabolism on cytosolic free Ca2+ oscillations in single hepatocytes, FEBS Lett., 312, 57, 10.1016/0014-5793(92)81409-F Meyer, 1989, A derivative of staurosporine (CGP 41 251) shows selectivity for protein kinase C inhibition and in vitro antiproliferative as well as in vivo anti-tumour activity, Int. J. Cancer, 43, 851, 10.1002/ijc.2910430519 Ruegg, 1989, Staurosporine K-252 and UCN-01: potent but non-specific inhibitors of protein kinases, Trends Pharmacol. Sci., 10, 218, 10.1016/0165-6147(89)90263-0 Davis, 1989, Potent selective inhibitors of protein kinase C, FEBS Lett., 259, 61, 10.1016/0014-5793(89)81494-2 Toullec, 1991, The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C, J. Biol. Chem., 266, 15771, 10.1016/S0021-9258(18)98476-0 Herbert, 1990, Chelerythrine is a potent and specific inhibitor of protein kinase C, Biochem. Biophys. Res. Commun., 172, 993, 10.1016/0006-291X(90)91544-3 House, 1987, Protein kinase C contains a pseudosubstrate prototope in its regulatory domain, Science, 238, 1726, 10.1126/science.3686012 House, 1990, Protein kinase C pseudosubstrate prototope: structure-function relationships, Cell. Signal., 2, 187, 10.1016/0898-6568(90)90022-3 Alexander, 1989, A protein kinase C pseudosubstrate peptide inhibits phosphorylation of the CD3 antigen in streptolysin-O-permeabilised human T lymphocytes, Biochem. J., 260, 893, 10.1042/bj2600893 Alexander, 1990, A method for measuring protein kinase C activity in permeabilised T lymphocytes by using peptide substrates. Evidence for multiple pathways of kinase activation, Biochem. J., 268, 303, 10.1042/bj2680303 Eichholtz, 1993, A myristoylated pseudosubstrate peptide, a novel protein kinase C inhibitor, J. Biol. Chem., 268, 1982, 10.1016/S0021-9258(18)53951-X Malinow, 1989, Inhibition of postsynaptic PKC or CaMKII blocks induction but not expression of LTP, Science, 245, 862, 10.1126/science.2549638 Rane, 1989, Specific inhibitors of protein kinase C block transmitter-induced modulation of sensory neuron calcium current, Neuron, 3, 239, 10.1016/0896-6273(89)90037-8 Ioannides, 1990, Inhibition of IL-2 receptor induction and IL-2 production in the human leukaemic cell line Jurkat by a novel peptide inhibitor of protein kinase C, Cell. Immunol., 131, 242, 10.1016/0008-8749(90)90250-U O'Brian, 1991, A novel N-myristoylated synthetic octapeptide inhibits protein kinase C activity and partially reverses murine fibrosarcoma cell resistance to adriamycin, Invest. New Drugs, 9, 169, 10.1007/BF00175084 Merrill, 1989, Modulation of protein kinase C and diverse cell functions by sphingosine — a pharmacologically interesting compound linking sphingolipids and signal transduction, Biochim. Biophys. Acta, 1010, 131, 10.1016/0167-4889(89)90152-3 Sando, 1992, Role of co-factors in protein kinase C activation, Cell. Signal., 4, 595, 10.1016/0898-6568(92)90041-6 Nishizuka, 1984, The role of protein kinase C in cell surface signal transduction and tumour promotion, Nature, 308, 693, 10.1038/308693a0 Asaoka, 1991, Metabolic rate of membrane permeant diacylglycerol and its relation to human resting T-lymphocyte activation, 88, 8681 Nishizuka, 1992, Intracellular signalling by hydrolysis of phospholipids and activation of protein kinase C, Science, 258, 607, 10.1126/science.1411571 Billah, 1990, The regulation and cellular functions of phosphatidylcholine hydrolysis, Biochem. J., 269, 281, 10.1042/bj2690281 Exton, 1990, Signalling through phosphatidylcholine breakdown, J. Biol. Chem., 265, 1, 10.1016/S0021-9258(19)40184-1 Augert, 1989, Hormonal stimulation of diacylglycerol formation in hepatocytes. Evidence for phosphatidylcholine breakdown, J. Biol. Chem., 264, 21689, 10.1016/S0021-9258(20)88241-6 Kanoh, 1990, Diacylglycerol kinase: a key modulator of signal transduction?, Trends Biochem. Sci., 15, 47, 10.1016/0968-0004(90)90172-8 Kanoh, 1989, Phosphorylation of diacylglycerol kinase in vitro by protein kinase C, Biochem. J., 258, 455, 10.1042/bj2580455 Schaap, 1993, Diacylglycerol kinase is phosphorylated in vivo upon stimulation of the epidermal growth factor receptor and serine/threonine kinases, including protein kinase C-ϵ, Biochem. J., 289, 875, 10.1042/bj2890875 Kanoh, 1993, Diacylglycerol kinase and phosphatidic acid phosphatase — enzymes metabolising lipid second messengers, Cell. Signal., 5, 495, 10.1016/0898-6568(93)90045-N Van der Bend, 1994, Diacylglycerol kinase in receptor-stimulated cells converts its substrate in a topologically restricted manner, J. Biol. Chem., 269, 4098, 10.1016/S0021-9258(17)41748-0 Gomez-Munoz, 1992, Effects of okadaic acid on the activities of two distinct phosphatidate phosphohydrolases in rat hepatocytes, FEBS Lett., 301, 103, 10.1016/0014-5793(92)80219-7 Ko, 1990, Antiplatelet effects of chelerythrine chloride isolated from Zanthoxylum simulans, Biochim. Biophys. Acta, 1052, 360, 10.1016/0167-4889(90)90144-3 Hug, 1993, Protein kinase C isozymes: divergence in signal transduction?, Biochem. J., 291, 329, 10.1042/bj2910329 Dekker, 1994, Protein kinase C — a question of specificity, Trends Biochem. Sci., 19, 73, 10.1016/0968-0004(94)90038-8 Sakane, 1990, Porcine diacylglycerol kinase sequence has zinc finger and E-F hand motifs, Nature, 344, 345, 10.1038/344345a0 Goto, 1993, Molecular cloning and expression of a 90-kDa diacylglycerol kinase that predominantly localises in neurons, 90, 7598 Sakane, 1989, Different effects of sphingosine, R59022 and anionic amphiphiles on two diacylglycerol kinase isozymes purified from porcine thymus cytosol, FEBS Lett., 255, 409, 10.1016/0014-5793(89)81134-2 Yamada, 1993, The different effects of sphingosine on diacylglycerol kinase isozymes in Jurkat cells, a human T-cell line, Biochim. Biophys. Acta, 1169, 211, 10.1016/0005-2760(93)90242-2 Mullmann, 1991, Sphingosine inhibits phosphatidate phosphohydrolase in human neutrophils by a protein kinase C-independent mechanism, J. Biol. Chem., 266, 2013, 10.1016/S0021-9258(18)52201-8 Chao, 1994, Sphingosinemediated phosphatidylinositol metabolism and calcium mobilisation, J. Biol. Chem., 269, 5849, 10.1016/S0021-9258(17)37539-7