Bone Size and Quality Regulation: Concerted Actions of mTOR in Mesenchymal Stromal Cells and Osteoclasts
Hongguang Wu1,2, Zhixiang Wu1,2, Ping Li2, Qian Cong2, Rongrong Chen3, Wenrui Xu4, Soma Biswas2, Huijuan Liu1,2, Xuechun Xia2, Shanshan Li5, Weiwei Hu5, Zhenlin Zhang5, Samy L. Habib6, Lingli Zhang7, Jun Zou7, Hongbing Zhang3, Weihong Zhang4, Baojie Li1,2,7
1Bio-X-Renji Hospital Research Center, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China
2Key Laboratory for the Genetics of Developmental and Neuropsychiatric Disorders, Bio-X Institutes, Ministry of Education, Shanghai Jiao Tong University, Shanghai 200240, China
3State Key Laboratory of Medical Molecular Biology, Department of Physiology, Institute of Basic Medical Sciences, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China
4Department of Radiology, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China
5Research Unit, Department of Osteoporosis and Bone Diseases, Shanghai Jiao Tong University Affiliated with Sixth People's Hospital, 600 Yishan Road, Shanghai 200233, China
6Department of Cellular and Structural Biology, South Texas Veterans Health Care System, San Antonio, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
7Scientific Research Department, Shanghai University of Sport, 399 Changhai Road, Yangpu District, Shanghai, 200438, China