Bone Sialoprotein Shows Enhanced Expression in Early, High-Proliferation Stages of Three-Dimensional Spheroid Cell Cultures of Breast Cancer Cell Line MDA-MB-231
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Wu, 2016, Pattern of local recurrence and distant metastasis in breast cancer by molecular subtype, Cureus, 8, e924, 10.7759/cureus.924
Chen, 2017, Comparison of patterns and prognosis among distant metastatic breast cancer patients by age groups: a SEER population-based analysis, Sci Rep., 7, 9254, 10.1038/s41598-017-10166-8
Savci-Heijink, 2015, Retrospective analysis of metastatic behaviour of breast cancer subtypes, Breast Cancer Res Treat., 150, 547, 10.1007/s10549-015-3352-0
Langley, 2011, The seed and soil hypothesis revisited-the role of tumor-stroma interactions in metastasis to different organs, Int J Cancer, 128, 2527, 10.1002/ijc.26031
Mundy, 2002, Metastasis to bone: causes, consequences and therapeutic opportunities, Nat Rev Cancer, 2, 584, 10.1038/nrc867
Raymaekers, 2015, The vasculature: a vessel for bone metastasis, Bonekey Rep., 4, 742, 10.1038/bonekey.2015.111
Arneson, 2012, Estimated number of prevalent cases of metastatic bone disease in the US adult population, Clin Epidemiol., 4, 87, 10.2147/CLEP.S28339
Obenauf, 2015, Surviving at a distance: organ-specific metastasis, Trends Cancer, 1, 76, 10.1016/j.trecan.2015.07.009
Liu, 2008, Humoral bone morphogenetic protein 2 is sufficient for inducing breast cancer microcalcification, Mol Imaging, 7, 175, 10.2310/7290.2008.00018A
Chen, 2010, Breast cancer metastasis to the bone: mechanisms of bone loss, Breast Cancer Res., 12, 215, 10.1186/bcr2781
Coleman, 2001, Metastatic bone disease: clinical features, pathophysiology and treatment strategies, Cancer Treat Rev., 27, 165, 10.1053/ctrv.2000.0210
Coleman, 2006, Clinical features of metastatic bone disease and risk of skeletal morbidity, Clin Cancer Res., 12, 6243s, 10.1158/1078-0432.CCR-06-0931
Kingsley, 2007, Molecular biology of bone metastasis, Mol Cancer Ther., 6, 2609, 10.1158/1535-7163.MCT-07-0234
Raggatt, 2010, Cellular and molecular mechanisms of bone remodeling, J Biol Chem., 285, 25103, 10.1074/jbc.R109.041087
Kakonen, 2003, Mechanisms of osteolytic bone metastases in breast carcinoma, Cancer, 97, 834, 10.1002/cncr.11132
Kang, 2003, A multigenic program mediating breast cancer metastasis to bone, Cancer Cell, 3, 537, 10.1016/S1535-6108(03)00132-6
Köhrmann, 2009, Expression of matrix metalloproteinases (MMPs) in primary human breast cancer and breast cancer cell lines: new findings and review of the literature, BMC Cancer, 9, 188, 10.1186/1471-2407-9-188
Esquivel-Velázquez, 2015, The role of cytokines in breast cancer development and progression, J Interf Cytokine Res., 35, 1, 10.1089/jir.2014.0026
Zhao, 2018, The role of osteopontin in the progression of solid organ tumour, Cell Death Dis., 9, 356, 10.1038/s41419-018-0391-6
Bellahcène, 1996, Detection of bone sialoprotein in human breast cancer tissue and cell lines at both protein and messenger ribonucleic acid levels, Lab Invest., 75, 203
Merdad, 2014, Expression of matrix metalloproteinases (MMPs) in primary human breast cancer: MMP-9 as a potential biomarker for cancer invasion and metastasis, Anticancer Res., 34, 1355
Shiozawa, 2015, Bone marrow as a metastatic niche for disseminated tumor cells from solid tumors, Bonekey Rep., 4, 689, 10.1038/bonekey.2015.57
Shao, 2013, Hematopoietic stem cell senescence and cancer therapy-induced long-term bone marrow injury, Transl Cancer Res., 2, 397, 10.3978/j.issn.2218-676X.2013.07.03
Herring, 1972, The Biochemistry and Physiology of Bone
Fisher, 2003, Six genes expressed in bones and teeth encode the current members of the SIBLING family of proteins, Connect Tissue Res., 44, 33, 10.1080/713713644
Bellahcène, 2008, Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancer, Nat Rev Cancer, 8, 212, 10.1038/nrc2345
Fisher, 2001, Flexible structures of SIBLING proteins, bone sialoprotein, and osteopontin, Biochem Biophys Res Commun., 280, 460, 10.1006/bbrc.2000.4146
Ogbureke, 2004, Expression of SIBLINGs and their partner MMPs in salivary glands, J Dent Res., 83, 664, 10.1177/154405910408300902
Ogbureke, 2005, Renal expression of SIBLING proteins and their partner matrix metalloproteinases (MMPs), Kidney Int., 68, 155, 10.1111/j.1523-1755.2005.00389.x
Ogbureke, 2007, Up-regulation of SIBLING proteins and correlation with cognate MMP expression in oral cancer, Oral Oncol., 43, 920, 10.1016/j.oraloncology.2006.11.011
Bianco, 1991, Expression of bone sialoprotein (BSP) in developing human tissues, Calcif Tissue Int., 49, 421, 10.1007/BF02555854
Oldberg, 1988, The primary structure of a cell-binding bone sialoprotein, J Biol Chem., 263, 19430, 10.1016/S0021-9258(19)77651-0
Hattar, 2005, Potential of biomimetic surfaces to promote in vitro osteoblast-like cell differentiation, Biomaterials, 26, 839, 10.1016/j.biomaterials.2004.03.026
Mizuno, 2000, Bone sialoprotein (BSP) is a crucial factor for the expression of osteoblastic phenotypes of bone marrow cells cultured on type I collagen matrix, Calcif Tissue Int., 66, 388, 10.1007/s002230010078
Zepp, 2018, IDK1 is a rat monoclonal antibody against hypoglycosylated bone sialoprotein with application as biomarker and therapeutic agent in breast cancer skeletal metastasis, J Pathol Clin Res., 4, 55, 10.1002/cjp2.88
Wuttke, 2001, Structural characterization of human recombinant and bone-derived bone sialoprotein. Functional implications for cell attachment and hydroxyapatite binding, J Biol Chem., 276, 36839, 10.1074/jbc.M105689200
Raynal, 1996, Bone sialoprotein stimulates in vitro bone resorption, Endocrinology, 137, 2347, 10.1210/endo.137.6.8641185
Sung, 1998, Bone sialoprotein supports breast cancer cell adhesion proliferation and migration through differential usage of the alpha(v)beta3 and alpha(v)beta5 integrins, J Cell Physiol., 176, 482, 10.1002/(SICI)1097-4652(199809)176:3<482::AID-JCP5>3.0.CO;2-K
Karadag, 2004, Bone sialoprotein, matrix metalloproteinase 2, and alpha(v)beta3 integrin in osteotropic cancer cell invasion, J Natl Cancer Inst., 96, 956, 10.1093/jnci/djh169
Fedarko, 2000, Factor H binding to bone sialoprotein and osteopontin enables tumor cell evasion of complement-mediated attack, J Biol Chem., 275, 16666, 10.1074/jbc.M001123200
Diel, 1999, Serum bone sialoprotein in patients with primary breast cancer is a prognostic marker for subsequent bone metastasis, Clin Cancer Res., 5, 3914
Loibl, 2006, [PTHrP and bone sialoprotein as prognostic markers for developing bone metastases in breast cancer patients], Zentralbl Gynakol., 128, 330, 10.1055/s-2006-942314
Adwan, 2004, Downregulation of osteopontin and bone sialoprotein II is related to reduced colony formation and metastasis formation of MDA-MB-231 human breast cancer cells, Cancer Gene Ther., 11, 109, 10.1038/sj.cgt.7700659
Bäuerle, 2006, Treatment of bone metastasis induced by MDA-MB-231 breast cancer cells with an antibody against bone sialoprotein, Int J Oncol., 28, 573, 10.3892/ijo.28.3.573
Ducy, 1997, Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation, Cell, 89, 747, 10.1016/S0092-8674(00)80257-3
Lee, 2000, Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12, Mol Cell Biol., 20, 8783, 10.1128/MCB.20.23.8783-8792.2000
Lee, 2002, Both the Smad and p38 MAPK pathways play a crucial role in Runx2 expression following induction by transforming growth factor-beta and bone morphogenetic protein, Oncogene, 21, 7156, 10.1038/sj.onc.1205937
Qiao, 2004, Insulin-like growth factor-1 regulates endogenous RUNX2 activity in endothelial cells through a phosphatidylinositol 3-kinase/ERK-dependent and Akt-independent signaling pathway, J Biol Chem., 279, 42709, 10.1074/jbc.M404480200
Cohen-Solal, 2015, RUNX2 and the PI3K/AKT axis reciprocal activation as a driving force for tumor progression, Mol Cancer, 14, 137, 10.1186/s12943-015-0404-3
Ogata, 1997, Transforming growth factor-beta 1 regulation of bone sialoprotein gene transcription: identification of a TGF-beta activation element in the rat BSP gene promoter, J Cell Biochem., 65, 501, 10.1002/(SICI)1097-4644(19970615)65:4<501::AID-JCB6>3.0.CO;2-S
Ogata, 2008, Bone sialoprotein and its transcriptional regulatory mechanism, J Periodontal Res., 43, 127, 10.1111/j.1600-0765.2007.01014.x
Nakayama, 2006, Insulin-like growth factor-I increases bone sialoprotein (BSP) expression through fibroblast growth factor-2 response element and homeodomain protein-binding site in the proximal promoter of the BSP gene, J Cell Physiol., 208, 326, 10.1002/jcp.20664
Pampaloni, 2007, The third dimension bridges the gap between cell culture and live tissue, Nat Rev Mol Cell Biol., 8, 839, 10.1038/nrm2236
Nath, 2016, Three-dimensional culture systems in cancer research: focus on tumor spheroid model, Pharmacol Ther., 163, 94, 10.1016/j.pharmthera.2016.03.013
Yamada, 2007, Modeling tissue morphogenesis and cancer in 3D, Cell, 130, 601, 10.1016/j.cell.2007.08.006
Kim, 2005, Three-dimensional tissue culture models in cancer biology, Semin Cancer Biol., 15, 365, 10.1016/j.semcancer.2005.05.002
Longati, 2013, 3D pancreatic carcinoma spheroids induce a matrix-rich, chemoresistant phenotype offering a better model for drug testing, BMC Cancer, 13, 95, 10.1186/1471-2407-13-95
Debnath, 2003, Morphogenesis and oncogenesis of MCF-10A mammary epithelial acini grown in three-dimensional basement membrane cultures, Methods, 30, 256, 10.1016/S1046-2023(03)00032-X
Friedrich, 2009, Spheroid-based drug screen: considerations and practical approach, Nat Protoc., 4, 309, 10.1038/nprot.2008.226
Ivascu, 2006, Rapid generation of single-tumor spheroids for high-throughput cell function and toxicity analysis, J Biomol Screen, 11, 922, 10.1177/1087057106292763
Li, 2011, 3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen, J Biomol Screen, 16, 141, 10.1177/1087057110392995
Chen, 2014, High-throughput image analysis of tumor spheroids: a user-friendly software application to measure the size of spheroids automatically and accurately, J Vis Exp., 8, e51639, 10.3791/51639
Ivanov, 2014, Multiplexing spheroid volume, resazurin and acid phosphatase viability assays for high-throughput screening of tumour spheroids and stem cell neurospheres, PLoS ONE, 9, e103817, 10.1371/journal.pone.0103817
Piccinini, 2015, Cancer multicellular spheroids: volume assessment from a single 2D projection, Comput Methods Prog Biomed., 118, 95, 10.1016/j.cmpb.2014.12.003
Piccinini, 2015, AnaSP: a software suite for automatic image analysis of multicellular spheroids, Comput Methods Prog Biomed., 119, 43, 10.1016/j.cmpb.2015.02.006
Laemmli, 1970, Cleavage of structural proteins during the assembly of the head of bacteriophage T4, Nature, 227, 680, 10.1038/227680a0
Barnes, 2003, Osteoblast-related transcription factors Runx2 (Cbfa1/AML3) and MSX2 mediate the expression of bone sialoprotein in human metastatic breast cancer cells, Cancer Res., 63, 2631
Selvamurugan, 2004, Smad3 interacts with JunB and Cbfa1/Runx2 for transforming growth factor-β1-stimulated collagenase-3 expression in human breast cancer cells, J Biol Chem., 279, 27764, 10.1074/jbc.M312870200
Gentry, 1988, Molecular events in the processing of recombinant type 1 pre-pro-transforming growth factor beta to the mature polypeptide, Mol Cell Biol., 8, 4162, 10.1128/MCB.8.10.4162
Duguay, 1999, Post-translational processing of insulin-like growth factors, Horm Metab Res., 31, 43, 10.1055/s-2007-978697
Raghavan, 2016, Comparative analysis of tumor spheroid generation techniques for differential in vitro drug toxicity, Oncotarget, 7, 16948, 10.18632/oncotarget.7659
Hagemann, 2017, Spheroid-based 3D cell cultures enable personalized therapy testing and drug discovery in head and neck cancer, Anticancer Res., 37, 2201, 10.21873/anticanres.11555
Carey, 2017, Three-dimensional collagen matrix induces a mechanosensitive invasive epithelial phenotype, Sci Rep., 7, 42088, 10.1038/srep42088
Cavo, 2018, A new cell-laden 3D alginate-matrigel hydrogel resembles human breast cancer cell malignant morphology, spread and invasion capability observed in vivo, Sci Rep., 8, 5333, 10.1038/s41598-018-23250-4
Cavo, 2016, Microenvironment complexity and matrix stiffness regulate breast cancer cell activity in a 3D in vitro model, Sci Rep., 6, 35367, 10.1038/srep35367
Kenny, 2007, The morphologies of breast cancer cell lines in three-dimensional assays correlate with their profiles of gene expression, Mol Oncol., 1, 84, 10.1016/j.molonc.2007.02.004
Rustamov, 2017, Long-term 3D culture of the SCC4 cell line using three different culture methods and initial seeding densities, J Cell Biotechnol., 3, 41, 10.3233/JCB-179005
Vukicevic, 1992, Identification of multiple active growth factors in basement membrane Matrigel suggests caution in interpretation of cellular activity related to extracellular matrix components, Exp Cell Res., 202, 1, 10.1016/0014-4827(92)90397-Q
Kleinman, 1982, Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma, Biochemistry, 21, 6188, 10.1021/bi00267a025
Gillette, 2003, Detection of matrix metalloproteinases (MMP), tissue inhibitor of metalloproteinase-2, urokinase and plasminogen activator inhibitor-1 within matrigel and growth factor-reduced matrigel basement membrane, Tumori, 89, 421, 10.1177/030089160308900415
Kibbey, 1994, Maintenance of the EHS sarcoma and Matrigel preparation, J Tiss Cult Methods, 16, 227, 10.1007/BF01540656
Edmondson, 2016, Influence of matrices on 3D-cultured prostate cancer cells' drug response and expression of drug-action associated proteins, PLoS ONE, 11, e0158116, 10.1371/journal.pone.0158116
Fridman, 1991, Enhanced tumor growth of both primary and established human and murine tumor cells in athymic mice after coinjection with Matrigel, J Natl Cancer Inst., 83, 769, 10.1093/jnci/83.11.769
Christensen, 2015, Non-invasive in vivo imaging and quantification of tumor growth and metastasis in rats using cells expressing far-red fluorescence protein, PLoS ONE, 10, e0132725, 10.1371/journal.pone.0132725
Nam, 2006, Bone sialoprotein mediates the tumor cell–targeted prometastatic activity of transforming growth factor β in a mouse model of breast cancer, Cancer Res., 66, 6327, 10.1158/0008-5472.CAN-06-0068
Kovacheva, 2014, Sustained conditional knockdown reveals intracellular bone sialoprotein as essential for breast cancer skeletal metastasis, Oncotarget, 5, 5510, 10.18632/oncotarget.2132
Zarzynska, 2014, Two Faces of TGF-Beta1 in breast cancer, Mediators Inflamm., 2014, 1, 10.1155/2014/141747