Body weight and risk of molecular breast cancer subtypes among postmenopausal Mediterranean women

Ferlay, 2007, Estimates of the cancer incidence and mortality in Europe in 2006, Ann Oncol, 18, 581, 10.1093/annonc/mdl498 Renehan, 2008, Body mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies, Lancet, 371, 569, 10.1016/S0140-6736(08)60269-X Basen-Engquist, 2011, Obesity and cancer risk: recent review and evidence, Curr Oncol Rep, 13, 71, 10.1007/s11912-010-0139-7 Haakinson, 2012, The impact of obesity on breast cancer: a retrospective review, Ann Surg Oncol, 19, 3012, 10.1245/s10434-012-2320-8 Crispo, 2013, Molecular profiles of screen detected vs. symptomatic breast cancer and their impact on survival: results from a clinical series, BMC Cancer, 13, 15, 10.1186/1471-2407-13-15 Khandekar, 2011, Molecular mechanisms of cancer development in obesity, Nat Rev Cancer, 11, 886, 10.1038/nrc3174 Tran, 1996, Insulin promotion of colon tumors in rats, Cancer Epidemiol Biomarkers Prev, 5, 1013 Giovannucci, 1995, Insulin and colon cancer, Cancer Causes Control, 6, 164, 10.1007/BF00052777 Kaaks, 2001, Energy balance and cancer: the role of insulin and insulin-like growth factor-I, Proc Nutr Soc, 60, 91, 10.1079/PNS200070 Vigneri, 2009, Diabetes and cancer, Endocr Relat Cancer, 16, 1103, 10.1677/ERC-09-0087 Capasso, 2013, Homeostasis model assessment to detect insulin resistance and identify patients at high risk of breast cancer development: National Cancer Institute of Naples experience, J Exp Clin Cancer Res, 32, 14, 10.1186/1756-9966-32-14 Jee, 2005, Fasting serum glucose level and cancer risk in Korean men and women, JAMA, 293, 194, 10.1001/jama.293.2.194 Rapp, 2006, Fasting blood glucose and cancer risk in a cohort of more than 140,000 adults in Austria, Diabetologia, 49, 945, 10.1007/s00125-006-0207-6 Stattin, 2007, Prospective study of hyperglycemia and cancer risk, Diabetes Care, 30, 561, 10.2337/dc06-0922 Larsson, 2007, Diabetes mellitus and risk of breast cancer: a meta-analysis, Int J Cancer, 121, 856, 10.1002/ijc.22717 Larsson, 2005, Diabetes mellitus and risk of colorectal cancer: a meta-analysis, J Natl Cancer Inst, 97, 1679, 10.1093/jnci/dji375 Prat, 2010, Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer, Breast Cancer Res, 12, R68, 10.1186/bcr2635 Goldhirsch, 2013, Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013, Ann Oncol, 24, 2206, 10.1093/annonc/mdt303 Perou, 2000, Molecular portraits of human breast tumours, Nature, 406, 747, 10.1038/35021093 Sorlie, 2001, Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications, Proc Natl Acad Sci U S A, 98, 10869, 10.1073/pnas.191367098 Millikan, 2008, Epidemiology of basal-like breast cancer, Breast Cancer Res Treat, 109, 123, 10.1007/s10549-007-9632-6 Tamimi, 2012, Traditional breast cancer risk factors in relation to molecular subtypes of breast cancer, Breast Cancer Res Treat, 131, 159, 10.1007/s10549-011-1702-0 National Cholesterol Education Program Expert Panel on Detection E, 2002, Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report, Circulation, 106, 3143, 10.1161/circ.106.25.3143 Goodwin, 2002, Fasting insulin and outcome in early-stage breast cancer: results of a prospective cohort study, J Clin Oncol, 20, 42, 10.1200/JCO.20.1.42 Matthews, 1985, Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man, Diabetologia, 28, 412, 10.1007/BF00280883 Gayoso-Diz, 2013, Insulin resistance (HOMA-IR) cut-off values and the metabolic syndrome in a general adult population: effect of gender and age: EPIRCE cross-sectional study, BMC Endocr Disord, 13, 47, 10.1186/1472-6823-13-47 Colditz, 2004, Risk factors for breast cancer according to estrogen and progesterone receptor status, J Natl Cancer Inst, 96, 218, 10.1093/jnci/djh025 Enger, 2000, Body size, physical activity, and breast cancer hormone receptor status: results from two case-control studies, Cancer Epidemiol Biomarkers Prev, 9, 681 Potter, 1995, Progesterone and estrogen receptors and mammary neoplasia in the Iowa Women's Health Study: how many kinds of breast cancer are there?, Cancer Epidemiol Biomarkers Prev, 4, 319 Cotterchio, 2003, Hormonal factors and the risk of breast cancer according to estrogen- and progesterone-receptor subgroup, Cancer Epidemiol Biomarkers Prev, 12, 1053 Huang, 2000, Hormone-related factors and risk of breast cancer in relation to estrogen receptor and progesterone receptor status, Am J Epidemiol, 151, 703, 10.1093/oxfordjournals.aje.a010265 Rosenberg, 2006, Risk factors for hormone receptor-defined breast cancer in postmenopausal women, Cancer Epidemiol Biomarkers Prev, 15, 2482, 10.1158/1055-9965.EPI-06-0489 Suzuki, 2006, Body weight and postmenopausal breast cancer risk defined by estrogen and progesterone receptor status among Swedish women: a prospective cohort study, Int J Cancer, 119, 1683, 10.1002/ijc.22034 Capasso, 2014, Metabolic syndrome-breast cancer link varies by intrinsic molecular subtype, Diabetol Metabol Syndr, 6, 105, 10.1186/1758-5996-6-105 Phipps, 2008, Body size and risk of luminal, HER2-overexpressing, and triple-negative breast cancer in postmenopausal women, Cancer Epidemiol Biomarkers Prev, 17, 2078, 10.1158/1055-9965.EPI-08-0206 Wang, 2015, Aromatase overexpression in dysfunctional adipose tissue links obesity to postmenopausal breast cancer, J Steroid Biochem Mol Biol, 10.1016/j.jsbmb.2015.07.008 Bosetti, 2012, Diabetes mellitus and cancer risk in a network of case-control studies, Nutr Cancer, 64, 643, 10.1080/01635581.2012.676141 Campbell, 2012, Diabetes and cause-specific mortality in a prospective cohort of one million U.S. adults, Diabetes Care, 35, 1835, 10.2337/dc12-0002 Boyle, 2013, Blood glucose concentrations and breast cancer risk in women without diabetes: a meta-analysis, Eur J Nutr, 52, 1533, 10.1007/s00394-012-0460-z Calip, 2015, Associations between diabetes medication use and risk of second breast cancer events and mortality, Cancer Causes Control, 26, 1065, 10.1007/s10552-015-0599-z Barba, 2012, Fasting glucose and treatment outcome in breast and colorectal cancer patients treated with targeted agents: results from a historic cohort, Ann Oncol, 23, 1838, 10.1093/annonc/mdr540 Zelzer, 1998, Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT, EMBO J, 17, 5085, 10.1093/emboj/17.17.5085 Pollak, 2008, Insulin and insulin-like growth factor signalling in neoplasia, Nat Rev Cancer, 8, 915, 10.1038/nrc2536 Coppola, 1994, A functional insulin-like growth factor I receptor is required for the mitogenic and transforming activities of the epidermal growth factor receptor, Mol Cell Biol, 14, 4588, 10.1128/MCB.14.7.4588 Roudabush, 2000, Transactivation of the EGF receptor mediates IGF-1-stimulated shc phosphorylation and ERK1/2 activation in COS-7 cells, J Biol Chem, 275, 22583, 10.1074/jbc.M002915200 Gallardo, 2012, Increased signalling of EGFR and IGF1R, and deregulation of PTEN/PI3K/Akt pathway are related with trastuzumab resistance in HER2 breast carcinomas, Br J Cancer, 106, 1367, 10.1038/bjc.2012.85 Nahta, 2012, Deciphering the role of insulin-like growth factor-I receptor in trastuzumab resistance, Chemother Res Pract, 2012, 648965 Ye, 2014, Epigenetic silencing of miR-375 induces trastuzumab resistance in HER2-positive breast cancer by targeting IGF1R, BMC Cancer, 14, 134, 10.1186/1471-2407-14-134