Blood flow restriction in human skeletal muscle during rest periods after high-load resistance training down-regulates miR-206 and induces Pax7

Takarada, 2002, Effects of resistance exercise combined with vascular occlusion on muscle function in athletes, Eur J Appl Physiol, 86, 308, 10.1007/s00421-001-0561-5 Fujita, 2007, Blood flow restriction during low-intensity resistance exercise increases S6K1 phosphorylation and muscle protein synthesis, J Appl Physiol (1985), 103, 903, 10.1152/japplphysiol.00195.2007 Bahreinipour, 2018, Mild aerobic training with blood flow restriction increases the hypertrophy index and MuSK in both slow and fast muscles of old rats: Role of PGC-1α, Life Sci, 202, 103, 10.1016/j.lfs.2018.03.051 Yasuda, 2012, Effects of blood flow restricted low-intensity concentric or eccentric training on muscle size and strength, PLoS One, 7, e52843, 10.1371/journal.pone.0052843 Gundermann, 2012, Reactive hyperemia is not responsible for stimulating muscle protein synthesis following blood flow restriction exercise, J Appl Physiol (1985), 112, 1520, 10.1152/japplphysiol.01267.2011 Suga, 2009, Intramuscular metabolism during low-intensity resistance exercise with blood flow restriction, J Appl Physiol (1985), 106, 1119, 10.1152/japplphysiol.90368.2008 Natsume, 2015, Effects of electrostimulation with blood flow restriction on muscle size and strength, Med Sci Sports Exerc, 47, 2621, 10.1249/MSS.0000000000000722 Fatela, 2018, Acute neuromuscular adaptations in response to low-intensity blood-flow restricted exercise and high-intensity resistance exercise: Are there any differences?, J Strength Cond Res, 32, 902, 10.1519/JSC.0000000000002022 Martín-Hernández, 2017, Adaptation of perceptual responses to low-load blood flow restriction training, J Strength Cond Res, 31, 765, 10.1519/JSC.0000000000001478 Conceição, 2016, Attenuated PGC-1α isoforms following endurance exercise with blood flow restriction, Med Sci Sports Exerc, 48, 1699, 10.1249/MSS.0000000000000970 Lixandrão, 2015, Effects of exercise intensity and occlusion pressure after 12 weeks of resistance training with blood-flow restriction, Eur J Appl Physiol, 115, 2471, 10.1007/s00421-015-3253-2 Takada, 2012, Blood flow restriction exercise in sprinters and endurance runners, Med Sci Sports Exerc, 44, 413, 10.1249/MSS.0b013e31822f39b3 Brandner, 2017, Delayed onset muscle soreness and perceived exertion after blood flow restriction exercise, J Strength Cond Res, 31, 3101, 10.1519/JSC.0000000000001779 Souza, 2019, Improvement of lower-body resistance-exercise performance with blood-flow restriction following acute caffeine intake, Int J Sports Physiol Perform, 14, 216, 10.1123/ijspp.2018-0224 Koltai, 2017, SIRT1 may play a crucial role in overload-induced hypertrophy of skeletal muscle, J Physiol, 595, 3361, 10.1113/JP273774 Bartel, 2009, MicroRNAs: Target recognition and regulatory functions, Cell, 136, 215, 10.1016/j.cell.2009.01.002 Radak, 2017, Exercise, oxidants, and antioxidants change the shape of the bell-shaped hormesis curve, Redox Biol, 12, 285, 10.1016/j.redox.2017.02.015 Levinger, 2009, The reliability of the 1RM strength test for untrained middle-aged individuals, J Sci Med Sport, 12, 310, 10.1016/j.jsams.2007.10.007 Kacin, 2011, Frequent low-load ischemic resistance exercise to failure enhances muscle oxygen delivery and endurance capacity, Scand J Med Sci Sports, 21, e231, 10.1111/j.1600-0838.2010.01260.x Noble, 1983, A category-ratio perceived exertion scale: Relationship to blood and muscle lactates and heart rate, Med Sci Sports Exerc, 15, 523, 10.1249/00005768-198315060-00015 Layne, 2017, Effects of blood-flow restriction on biomarkers of myogenesis in response to resistance exercise, Appl Physiol Nutr Metab, 42, 89, 10.1139/apnm-2016-0224 Petrick, 2019, Blood flow restricted resistance exercise and reductions in oxygen tension attenuate mitochondrial H2O2 emission rates in human skeletal muscle, J Physiol, 597, 3985, 10.1113/JP277765 Xie, 2012, miRDeepFinder: A miRNA analysis tool for deep sequencing of plant small RNAs, Plant Mol Biol, 80, 75, 10.1007/s11103-012-9885-2 Vandesompele, 2002, Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multipleinternal control genes, Genome Biol, 3, 10.1186/gb-2002-3-7-research0034 Andersen, 2004, Normalization of real-time quantitative reverse transcription-PCR data: A model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets, Cancer Res, 64, 5245, 10.1158/0008-5472.CAN-04-0496 Pfaffl, 2004, Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: Best Keeper—Excel-based tool using pair-wise correlations, Biotechnol Lett, 26, 509, 10.1023/B:BILE.0000019559.84305.47 Silver, 2006, Selection of housekeeping genes for gene expression studies in human reticulocytes using real-time PCR, BMC Mol Biol, 7, 33, 10.1186/1471-2199-7-33 Shelton, 2016, Robust generation and expansion of skeletal muscle progenitors and myocytes from human pluripotent stem cells, Methods, 101, 73, 10.1016/j.ymeth.2015.09.019 Hayashi, 2014, Systems biology strategy reveals PKCσ is key for sensitizing TRAIL-resistant human fibrosarcoma, Front Immunol, 5, 659 Xie, 2016, SIRT3 mediates the antioxidant effect of hydrogen sulfide in endothelial cells, Antioxid Redox Signal, 24, 329, 10.1089/ars.2015.6331 Bori, 2012, The effects of aging, physical training, and a single bout of exercise on mitochondrial protein expression in human skeletal muscle, Exp Gerontol, 47, 417, 10.1016/j.exger.2012.03.004 Koltai, 2018, Master athletes have higher miR-7, SIRT3 and SOD2 expression in skeletal muscle than age-matched sedentary controls, Redox Biol, 19, 46, 10.1016/j.redox.2018.07.022 Glover, 2011, IFN-γ attenuates hypoxia-inducible factor (HIF) activity in intestinal epithelial cells through transcriptional repression of HIF-1β, J Immunol, 186, 1790, 10.4049/jimmunol.1001442 Acs, 2014, High altitude exposure alters gene expression levels of DNA repair enzymes, and modulates fatty acid metabolism by SIRT4 induction in human skeletal muscle, Respir Physiol Neurobiol, 196, 33, 10.1016/j.resp.2014.02.006 Chock, 2010, BRCA1-IRIS overexpression promotes cisplatin resistance in ovarian cancer cells, Cancer Res, 70, 8782, 10.1158/0008-5472.CAN-10-1352 Radak, 2011, Age-dependent changes in 8-oxoguanine-DNA glycosylase activity are modulated by adaptive responses to physical exercise in human skeletal muscle, Free Radic Biol Med, 51, 417, 10.1016/j.freeradbiomed.2011.04.018 Guo, 2016, miR-23a/b regulates the balance between osteoblast and adipocyte differentiation in bone marrow mesenchymal stem cells, Bone Res, 4, 16022, 10.1038/boneres.2016.22 Livak, 2001, Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method, Methods, 25, 402, 10.1006/meth.2001.1262 Iida, 2011, Effects of walking with blood flow restriction on limb venous compliance in elderly subjects, Clin Physiol Funct Imaging, 31, 472, 10.1111/j.1475-097X.2011.01044.x Karabulut, 2011, Effects of high-intensity resistance training and low-intensity resistance training with vascular restriction on bone markers in older men, Eur J Appl Physiol, 111, 1659, 10.1007/s00421-010-1796-9 Fry, 2010, Blood flow restriction exercise stimulates mTORC1 signaling and muscle protein synthesis in older men, J Appl Physiol (1985), 108, 1199, 10.1152/japplphysiol.01266.2009 Clarkson, 2017, Blood flow restriction walking and physical function in older adults: A randomized control trial, J Sci Med Sport, 20, 1041, 10.1016/j.jsams.2017.04.012 Yasuda, 2016, Thigh muscle size and vascular function after blood flow-restricted elastic band training in older women, Oncotarget, 7, 33595, 10.18632/oncotarget.9564 Vechin, 2015, Comparisons between low-intensity resistance training with blood flow restriction and high-intensity resistance training on quadriceps muscle mass and strength in elderly, J Strength Cond Res, 29, 1071, 10.1519/JSC.0000000000000703 Centner, 2019, Effects of blood flow restriction training on muscular strength and hypertrophy in older individuals: A systematic review and meta-analysis, Sports Med, 49, 95, 10.1007/s40279-018-0994-1 Krustrup, 2009, Heterogeneous recruitment of quadriceps muscle portions and fibre types during moderate intensity knee-extensor exercise: Effect of thigh occlusion, Scand J Med Sci Sports, 19, 576, 10.1111/j.1600-0838.2008.00801.x D'Souza, 2017, Acute resistance exercise modulates microRNA expression profiles: Combined tissue and circulatory targeted analyses, PLoS One, 12 Winbanks, 2013, miR-206 represses hypertrophy of myogenic cells but not muscle fibers via inhibition of HDAC4, PLoS One, 8, e73589, 10.1371/journal.pone.0073589 Winbanks, 2011, TGF-beta regulates miR-206 and miR-29 to control myogenic differentiation through regulation of HDAC4, J Biol Chem, 286, 13805, 10.1074/jbc.M110.192625 Rao, 2006, Myogenic factors that regulate expression of muscle-specific microRNAs, Proc Natl Acad Sci U S A, 103, 8721, 10.1073/pnas.0602831103 Chen, 2010, microRNA-1 and microRNA-206 regulate skeletal muscle satellite cell proliferation and differentiation by repressing Pax7, J Cell Biol, 190, 867, 10.1083/jcb.200911036 Radak, 2013, Oxygen consumption and usage during physical exercise: The balance between oxidative stress and ROS-dependent adaptive signaling, Antioxid Redox Signal, 18, 1208, 10.1089/ars.2011.4498 Taylor, 2016, Acute and chronic effect of sprint interval training combined with postexercise blood-flow restriction in trained individuals, Exp Physiol, 101, 143, 10.1113/EP085293 Barnes, 2004, Repair and genetic consequences of endogenous DNA base damage in mammalian cells, Annu Rev Genet, 38, 445, 10.1146/annurev.genet.38.072902.092448 Motohashi, 2014, Muscle satellite cell heterogeneity and self-renewal, Front Cell Dev Biol, 2, 1, 10.3389/fcell.2014.00001 Snijders, 2015, Satellite cells in human skeletal muscle plasticity, Front Physiol, 6, 283, 10.3389/fphys.2015.00283 Toth, 2011, IL-6 induced STAT3 signalling is associated with the proliferation of human muscle satellite cells following acute muscle damage, PLoS One, 6, e17392, 10.1371/journal.pone.0017392