Blood-Contacting Biomaterials: In Vitro Evaluation of the Hemocompatibility

Marbod Weber1, Heidrun Steinle1, Sonia Golombek1, Ludmilla Hann1, Christian Schlensak1, Hans Peter Wendel1, Meltem Avci‐Adali1
1Department of Thoracic and Cardiovascular Surgery, University Hospital Tübingen, Germany

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Aguilar, 2002, Polymeric active coatings with functionality in vascular applications, J. Mater. Sci. Mater. Med., 13, 1099, 10.1023/A:1021100916920

Andersson, 2005, Binding of C3 fragments on top of adsorbed plasma proteins during complement activation on a model biomaterial surface, Biomaterials, 26, 1477, 10.1016/j.biomaterials.2004.05.011

Bae, 2003, Rapid increase in endothelial nitric oxide production by bradykinin is mediated by protein kinase A signaling pathway, Biochem. Biophys. Res. Commun., 306, 981, 10.1016/S0006-291X(03)01086-6

Balasubramanian, 2001, Effects of fibrinogen residence time and shear rate on the morphology and procoagulant activity of human platelets adherent to polymeric biomaterials, ASAIO J., 47, 354, 10.1097/00002480-200107000-00012

Ballet, 2010, Protein conformational changes induced by adsorption onto material surfaces: an important issue for biomedical applications of material science, Bull. Pol. Acad. Sci. Tech. Sci., 58, 303, 10.2478/v10175-010-0028-0

Basu, 2017, Hemocompatibility of Ca(2+) -crosslinked nanocellulose hydrogels: toward efficient management of hemostasis, Macromol. Biosci., 17, 10.1002/mabi.201700236

Biró, 2003, Human cell-derived microparticles promote thrombus formation in vivo in a tissue factor-dependent manner, J. Thromb. Haemost., 1, 2561, 10.1046/j.1538-7836.2003.00456.x

Blok, 2016, In vitro hemocompatibility testing: the importance of fresh blood, Biointerphases, 11, 029802, 10.1116/1.4941850

Brandt, 2000, The beta-thromboglobulins and platelet factor 4: blood platelet-derived CXC chemokines with divergent roles in early neutrophil regulation, J. Leukoc. Biol., 67, 471, 10.1002/jlb.67.4.471

Brass, 2013, Harnessing the platelet signaling network to produce an optimal hemostatic response, Hematol. Oncol. Clin. North Am., 27, 381, 10.1016/j.hoc.2013.02.002

Braune, 2013, Are there sufficient standards for the in vitro hemocompatibility testing of biomaterials?, Biointerphases, 8, 33, 10.1186/1559-4106-8-33

Brill, 2012, Neutrophil extracellular traps promote deep vein thrombosis in mice, J. Thromb. Haemost., 10, 136, 10.1111/j.1538-7836.2011.04544.x

Brinkmann, 2004, Neutrophil extracellular traps kill bacteria, Science, 303, 1532, 10.1126/science.1092385

Camci-Unal, 2013, Synthesis and characterization of hybrid hyaluronic acid-gelatin hydrogels, Biomacromolecules, 14, 1085, 10.1021/bm3019856

Cerda-Cristerna, 2011, Hemocompatibility assessment of poly (2-dimethylamino ethylmethacrylate)(PDMAEMA)-based polymers, J. Control. Release, 153, 269, 10.1016/j.jconrel.2011.04.016

Costabile, 2010, Measuring the 50% haemolytic complement (CH50) activity of serum, J. Vis. Exp, 37, 1923, 10.3791/1923

Dahlgren, 1999, Respiratory burst in human neutrophils, J. Immunol. Methods., 232, 3, 10.1016/S0022-1759(99)00146-5

Delgado-Rizo, 2017, Neutrophil extracellular traps and its implications in inflammation: an overview, Front. Immunol., 8, 81, 10.3389/fimmu.2017.00081

Dunkelberger, 2010, Complement and its role in innate and adaptive immune responses, Cell Res., 20, 34, 10.1038/cr.2009.139

Engberg, 2015, Prediction of inflammatory responses induced by biomaterials in contact with human blood using protein fingerprint from plasma, Biomaterials, 36, 55, 10.1016/j.biomaterials.2014.09.011

Engberg, 2011, Blood protein-polymer adsorption: implications for understanding complement-mediated hemoincompatibility, J. Biomed. Mater. Res. A, 97, 74, 10.1002/jbm.a.33030

Fatisson, 2011, Determination of surface-induced platelet activation by applying time-dependency dissipation factor versus frequency using quartz crystal microbalance with dissipation, J. R. Soc. Interface, 8, 988, 10.1098/rsif.2010.0617

Ferrer, 2013, Hemocompatibility and biocompatibility of antibacterial biomimetic hybrid films, Toxicol. Appl. Pharmacol., 272, 703, 10.1016/j.taap.2013.07.023

Fitch-Tewfik, 2013, Platelet granule exocytosis: a comparison with chromaffin cells, Front. Endocrinol., 77

Frenette, 2000, P-Selectin glycoprotein ligand 1 (PSGL-1) is expressed on platelets and can mediate platelet-endothelial interactions in vivo, J. Exp. Med., 191, 1413, 10.1084/jem.191.8.1413

Frohlich, 2016, Action of nanoparticles on platelet activation and plasmatic coagulation, Curr. Med. Chem., 23, 408, 10.2174/0929867323666160106151428

Golebiewska, 2015, Platelet secretion: from haemostasis to wound healing and beyond, Blood Rev., 29, 153, 10.1016/j.blre.2014.10.003

Gorbet, 2004, Biomaterial-associated thrombosis: roles of coagulation factors, complement, platelets and leukocytes, Biomaterials, 25, 5681, 10.1016/j.biomaterials.2004.01.023

Gorbet, 1999, Flow cytometric study of in vitro neutrophil activation by biomaterials, J. Biomed. Mater. Res. A, 44, 289, 10.1002/(SICI)1097-4636(19990305)44:3<289::AID-JBM7>3.0.CO;2-O

Gramegna, 2017, Neutrophil elastase in bronchiectasis, Respir. Res., 18, 211, 10.1186/s12931-017-0691-x

Hansson, 2007, Surface plasmon resonance detection of blood coagulation and platelet adhesion under venous and arterial shear conditions, Biosens. Bioelectron., 23, 261, 10.1016/j.bios.2007.04.009

Haycox, 1993, In vitro platelet interactions in whole human blood exposed to biomaterial surfaces: insights on blood compatibility, J. Biomed. Mater. Res. A, 27, 1181, 10.1002/jbm.820270909

25654940Biological Evaluation of Medical Devices2000

Ikeda, 1997, C5a induces tissue factor activity on endothelial cells, Thromb. Haemost., 77, 394, 10.1055/s-0038-1655974

Kälsch, 2007, Endotoxin-induced effects on platelets and monocytes in an in vivo model of inflammation, Basic Res. Cardiol., 102, 460, 10.1007/s00395-007-0667-y

Kappelmayer, 1993, Tissue factor is expressed on monocytes during simulated extracorporeal circulation, Circ. Res., 72, 1075, 10.1161/01.RES.72.5.1075

Kent, 2010, Microfluidic device to study arterial shear-mediated platelet-surface interactions in whole blood: reduced sample volumes and well-characterised protein surfaces, Biomed. Microdevices, 12, 987, 10.1007/s10544-010-9453-y

Kopp, 2002, Mechanism of complement activation during extracorporeal blood-biomaterial interaction: effects of heparin coated and uncoated surfaces, ASAIO J., 48, 598, 10.1097/00002480-200211000-00005

Kourtzelis, 2010, Complement anaphylatoxin C5a contributes to hemodialysis-associated thrombosis, Blood, 116, 631, 10.1182/blood-2010-01-264051

Kovach, 2014, The effects of PEG-based surface modification of PDMS microchannels on long-term hemocompatibility, J. Biomed. Mater. Res. A, 102, 4195, 10.1002/jbm.a.35090

Krajewski, 2013, Hemocompatibility evaluation of different silver nanoparticle concentrations employing a modified Chandler-loop in vitro assay on human blood, Acta Biomater., 9, 7460, 10.1016/j.actbio.2013.03.016

Kuhbier, 2017, Influence of direct or indirect contact for the cytotoxicity and blood compatibility of spider silk, J. Mater. Sci. Mater. Med, 28, 127, 10.1007/s10856-017-5936-1

Kunze, 2014, Real-time monitoring of surface-confined platelet activation on Tio2, Colloids Surf. B Biointerfaces, 116, 446, 10.1016/j.colsurfb.2014.01.025

Lackner, 2012, Hemocompatibility of inorganic physical vapor deposition (PVD) coatings on thermoplastic polyurethane polymers, J. Funct. Biomater., 3, 283, 10.3390/jfb3020283

Li, 2016, Endotoxin contamination: a key element in the interpretation of nanosafety studies, Nanomedicine, 11, 269, 10.2217/nnm.15.196

Liu, 2014, Blood compatible materials: state of the art, J. Mater. Chem. B, 2, 5718, 10.1039/C4TB00881B

Long, 2016, Contact system revisited: an interface between inflammation, coagulation, and innate immunity, J. Thromb. Haemost., 14, 427, 10.1111/jth.13235

Magalhães, 2007, Methods of endotoxin removal from biological preparations: a review, J. Pharm. Pharm. Sci., 10, 388

Maitz, 2017, Biocompatibility assessment of silk nanoparticles: hemocompatibility and internalization by human blood cells, Nanomedicine, 13, 2633, 10.1016/j.nano.2017.07.012

Mayer, 2009, The role of nanoparticle size in hemocompatibility, Toxicology, 258, 139, 10.1016/j.tox.2009.01.015

McClung, 2007, Fibrinolytic properties of lysine-derivatized polyethylene in contact with flowing whole blood (Chandler loop model), J. Biomed. Mater. Res. A, 81, 644, 10.1002/jbm.a.31018

Meyers, 1982, Comparative study of platelet dense granule constituents, Am. J. Physiol., 243, R454

Millar, 2016, The inflammatory response to extracorporeal membrane oxygenation (ECMO): a review of the pathophysiology, Crit. Care, 20, 387, 10.1186/s13054-016-1570-4

Mohan, 2013, In vitro hemocompatibility and vascular endothelial cell functionality on titania nanostructures under static and dynamic conditions for improved coronary stenting applications, Acta Biomater., 9, 9568, 10.1016/j.actbio.2013.08.023

Müller, 2009, Platelet polyphosphates are proinflammatory and procoagulant mediators in vivo, Cell, 139, 1143, 10.1016/j.cell.2009.11.001

Müller, 2011, Profiling of active thrombin in human blood by supramolecular complexes, Angew. Chem. Int. Ed. Engl., 50, 6075, 10.1002/anie.201007032

Müller, 2012, Dynamic in vitro hemocompatibility testing–improving the signal to noise ratio, Biomed. Eng., 57, 549, 10.1515/bmt-2012-4211

Nagy, 2017, Use of microfluidics to assess the platelet-based control of coagulation, Platelets, 28, 441, 10.1080/09537104.2017.1293809

Neun, 2011, Method for analysis of nanoparticle hemolytic properties in vitro, Characterization of Nanoparticles Intended for Drug Delivery, 215, 10.1007/978-1-60327-198-1_23

Newton, 2012, Signaling in innate immunity and inflammation, Cold Spring Harb. Perspect. Biol., 4, a006049, 10.1101/cshperspect.a006049

Nilsson, 2007, The role of complement in biomaterial-induced inflammation, Mol. Immunol., 44, 82, 10.1016/j.molimm.2006.06.020

Nguyen, 2016, Rupture forces among human blood platelets at different degrees of activation, Sci. Rep., 6, 25402, 10.1038/srep25402

Nordling, 2014, A novel in vitro model for studying the interactions between human whole blood and endothelium, J. Vis. Exp., 96, e52112, 10.3791/52112

Noubouossie, 2017, In vitro activation of coagulation by human neutrophil DNA and histone proteins but not neutrophil extracellular traps, Blood, 129, 1021, 10.1182/blood-2016-06-722298

Nygren, 2000, Different kinetics of the respiratory burst response in granulocytes, induced by serum from blood coagulated in contact with polymer materials, Biomaterials, 21, 173, 10.1016/S0142-9612(99)00146-5

Oikonomopoulou, 2010, Interactions between coagulation and complement—their role in inflammation, Semin. immunopathol, 34, 151, 10.1007/s00281-011-0280-x

Onasoga-Jarvis, 2014, Thrombin generation and fibrin formation under flow on biomimetic tissue factor-rich surfaces, J. Thromb. Haemost., 12, 373, 10.1111/jth.12491

Onasoga-Jarvis, 2013, The effect of factor VIII deficiencies and replacement and bypass therapies on thrombus formation under venous flow conditions in microfluidic and computational models, PLoS ONE, 8, e78732, 10.1371/journal.pone.0078732

Park, 1990, Morphological characterization of surface-induced platelet activation, Biomaterials, 11, 24, 10.1016/0142-9612(90)90047-T

Peckham, 1997, Hemocompatibility studies of surface-treated polyurethane-based chronic indwelling catheters, J. Biomater. Sci., 8, 847, 10.1163/156856297X00047

Podias, 1995, The effect of shear rate on the adhesion/activation of human platelets in flow through a closed-loop polymeric tubular system, J. Biomater. Sci, 6, 399, 10.1163/156856294X00392

Punet, 2015, Biomolecular functionalization for enhanced cell–material interactions of poly (methyl methacrylate) surfaces, Regen. Biomater., 2, 167, 10.1093/rb/rbv014

Qian, 2010, Hemolysis and acute kidney failure, Am. J. Kidney Dis., 56, 780, 10.1053/j.ajkd.2010.03.025

Ritis, 2006, A novel C5a receptor-tissue factor cross-talk in neutrophils links innate immunity to coagulation pathways, J. Immunol, 177, 4794, 10.4049/jimmunol.177.7.4794

Ritz-Timme, 1997, Genesis and diagnostic value of leukocyte and platelet accumulations around “air bubbles” in blood after venous air embolism, Int. J. Leg. Med., 111, 22, 10.1007/s004140050105

Roesslein, 2013, Comparability of in vitro tests for bioactive nanoparticles: a common assay to detect reactive oxygen species as an example, Int. J. Mol. Sci., 14, 24320, 10.3390/ijms141224320

Sanak, 2010, Assessment of hemocompatibility of materials with arterial blood flow by platelet functional tests, Bull. Polish Acad. Sci. Tech. Sci., 58, 317, 10.2478/v10175-010-0029-z

Schrottmaier, 2016, Platelet activation at the onset of human endotoxemia is undetectable in vivo, Platelets, 27, 479, 10.3109/09537104.2015

Sinn, 2010, Platelet aggregation monitoring with a newly developed quartz crystal microbalance system as an alternative to optical platelet aggregometry, Analyst, 135, 2930, 10.1039/c0an00474j

Sinn, 2011, A novel in vitro model for preclinical testing of the hemocompatibility of intravascular stents according to ISO 10993-4, J. Mater. Sci. Mater. Med., 22, 1521, 10.1007/s10856-011-4335-2

Sperling, 2017, A positively charged surface triggers coagulation activation through factor VII activating protease (FSAP), ACS Appl. Mater. Interfaces, 9, 40107, 10.1021/acsami.7b14281

Sperling, 2007, In vitro blood reactivity to hydroxylated and non-hydroxylated polymer surfaces, Biomaterials, 28, 3617, 10.1016/j.biomaterials.2007.04.041

Sreeramkumar, 2014, Neutrophils scan for activated platelets to initiate inflammation, Science, 346, 1234, 10.1126/science.1256478

Stadie, 1920, A method for the determination of methaemoglobin in the blood, J. Biol. Chem., 41, 237, 10.1016/S0021-9258(18)87221-0

Stang, 2014, Hemocompatibility testing according to ISO 10993-4: discrimination between pyrogen-and device-induced hemostatic activation, Mater. Sci. Eng. C, 42, 422, 10.1016/j.msec.2014.05.070

Stoll, 2017, Generation of Large-Scale DNA Hydrogels with excellent blood and cell compatibility, Macromol. Biosci., 17, 1600252, 10.1002/mabi.201600252

Streller, 2003, Design and evaluation of novel blood incubation systems for in vitro hemocompatibility assessment of planar solid surfaces, J. Biomed. Mater. Res. B Appl. Biomater., 66, 379, 10.1002/jbm.b.10016

Sukavaneshvar, 2017, Device thrombosis and pre-clinical blood flow models for assessing antithrombogenic efficacy of drug-device combinations, Adv. Drug Deliv. Rev., 112, 24, 10.1016/j.addr.2016.07.009

Teligui, 2016, Ex vivo simulation of cardiopulmonary bypass with human blood for hemocompatibility testing, Perfusion, 31, 376, 10.1177/0267659115599454

Théorêt, 2011, P-selectin ligation induces platelet activation and enhances microaggregate and thrombus formation, Thromb. Res., 128, 243, 10.1016/j.thromres.2011.04.018

Thorsen, 1993, Bubble-induced aggregation of platelets: effects of gas species, proteins, decompression, Undersea Hyperb. Med., 20, 101

Tiffany, 1989, Bradykinin stimulates tumor necrosis factor and interleukin-1 release from macrophages, FEBS Lett., 247, 189, 10.1016/0014-5793(89)81331-6

Totea, 2014, In vitro hemocompatibility and corrosion behavior of new Zr-binary alloys in whole human blood, Open Chem., 12, 796, 10.2478/s11532-014-0535-1

Vafa Homann, 2016, Improved ex vivo blood compatibility of central venous catheter with noble metal alloy coating, J. Biomed. Mater. Res. B Appl. Biomater., 104, 1359, 10.1002/jbm.b.33403

Van Kruchten, 2012, Measurement of whole blood thrombus formation using parallel-plate flow chambers–a practical guide, Platelets, 23, 229, 10.3109/09537104.2011.630848

van Oeveren, 2013, Obstacles in haemocompatibility testing, Scientifica, 2013, 392584, 10.1155/2013/392584

Van Oeveren, 2012, Comparison of modified chandler, roller pump, and ball valve circulation models for in vitro testing in high blood flow conditions: application in thrombogenicity testing of different materials for vascular applications, Int. J. Biomater., 2012, 673163, 10.1155/2012/673163

van Velzen, 2012, Multicolor flow cytometry for evaluation of platelet surface antigens and activation markers, Thromb. Res., 130, 92, 10.1016/j.thromres.2012.02.041

Vroman, 1980, Interaction of high molecular weight kininogen, factor XII, and fibrinogen in plasma at interfaces, Blood, 55, 156, 10.1182/blood.V55.1.156.156

Wachtfogel, 1995, Selective kallikrein inhibitors alter human neutrophil elastase release during extracorporeal circulation, Am. J. Physiol., 268, H1352

Wang, 2001, Surface coating of stearyl poly (ethylene oxide) coupling-polymer on polyurethane guiding catheters with poly (ether urethane) film-building additive for biomedical applications, Biomaterials, 22, 1549, 10.1016/S0142-9612(00)00311-2

Watanabe, 2003, Endotoxins stimulate neutrophil adhesion followed by synthesis and release of platelet-activating factor in microparticles, J. Biol. Chem., 278, 33161, 10.1074/jbc.M305321200

Westein, 2012, Monitoring in vitro thrombus formation with novel microfluidic devices, Platelets, 23, 501, 10.3109/09537104.2012.709653

Wetterö, 2000, Complement activation on immunoglobulin G-coated hydrophobic surfaces enhances the release of oxygen radicals from neutrophils through an actin-dependent mechanism, J. Biomed. Mater. Res., 51, 742, 10.1002/1097-4636(20000915)51:4<742::AID-JBM24>3.0.CO;2-D

Wijeyeratne, 2011, Anti-platelet therapy: ADP receptor antagonists, Br. J. Clin. Pharmacol., 72, 647, 10.1111/j.1365-2125.2011.03999.x

Wu, 2015, Contact pathway of coagulation and inflammation, Thromb. J., 13, 17, 10.1186/s12959-015-0048-y

Xiao, 2011, Synthesis and characterization of photocrosslinkable gelatin and silk fibroin interpenetrating polymer network hydrogels, Acta Biomater., 7, 2384, 10.1016/j.actbio.2011.01.016

Yau, 2015, Endothelial cell control of thrombosis, BMC Cardiovasc. Disord., 15, 130, 10.1186/s12872-015-0124-z

Zhang, 2015, A two-step protocol to remove endotoxins from human-like collagen, Sep. Sci. Technol., 50, 993, 10.1080/01496395.2014.978467

Zhang, 2017, The influence of surface chemistry on adsorbed fibrinogen conformation, orientation, fiber formation and platelet adhesion, Acta Biomater, 54, 164, 10.1016/j.actbio.2017.03.002

Zhao, 2011, Interaction of mesoporous silica nanoparticles with human red blood cell membranes: size and surface effects, ACS Nano, 5, 1366, 10.1021/nn103077k

Zhu, 2015, In microfluidico: recreating in vivo hemodynamics using miniaturized devices, Biorheology, 52, 303, 10.3233/BIR-15065

Zimmermann, 2007, Effect of biopassive and bioactive surface-coatings on the hemocompatibility of membrane oxygenators, J. Biomed. Mater. Res. B Appl. Biomater., 80, 433, 10.1002/jbm.b.30614