Blocking the CD154–CD40 interaction with anti-CD154 antibody differentially regulates interleukin-4 synthesis in T cells and IgE production in B cells

Hilton, 1996, Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor, Proc. Natl Acad. Sci. USA, 93, 497, 10.1073/pnas.93.1.497 Gauchat, 1997, A novel 4 kb interleukin-13 receptor a mRNA expressed in human B, T, and endothelial cells encoding an alternate type-II interleukin-4/interleukin-13 receptor, Eur. J. Immunol., 27, 971, 10.1002/eji.1830270425 Lane, 1992, Activated human T cells express a ligand for the human B cell-associated antigen CD40 which participates in T cell-dependent activation of B lymphocytes, Eur. J. Immunol., 22, 2573, 10.1002/eji.1830221016 Spriggs, 1992, Recombinant human CD40 ligand stimulates B cell proliferation and immunoglobulin E secretion, J. Exp. Med., 176, 1543, 10.1084/jem.176.6.1543 Lanier, 1995, CD80 (B7) CD86 (B70) provide similar costimulatory signals for T cell proliferation, cytokine production, and generation of CTL, J. Immunol., 154, 97, 10.4049/jimmunol.154.1.97 Blotta, 1996, Cross-linking of the CD40 ligand on human CD4+ T lymphocytes generates a costimulatory signal that up-regulates IL-4 synthesis, J. Immunol., 156, 3133, 10.4049/jimmunol.156.9.3133 Yanagihara, 1999, Production of IL-4 and expression of CD40 ligand by human CD8+T cells, J. Allergy Clin. Immunol., 103, S405, 10.1016/S0091-6749(99)70155-7 Yanagihara, 1994, Recombinant soluble form of the human high-affinity immunoglobulin E (IgE) receptor inhibits IgE production through its specific binding to IgE-bearing B cells, J. Clin. Invest., 94, 2162, 10.1172/JCI117574 Ikizawa, 1995, Inhibition of IL-4 receptor up-regulation on B cells by antisense oligodeoxynucleotide suppresses IL-4-induced human IgE production, Clin. Exp. Immunol., 100, 383, 10.1111/j.1365-2249.1995.tb03710.x Yanagihara, 1998, Cultured basophils but not cultured mast cells induce human IgE synthesis in B cells after immunologic stimulation, Clin. Exp. Immunol, 111, 136, 10.1046/j.1365-2249.1998.00474.x Roy, 1995, Studies on the interdependence of gp39 and B7 expression and function during antigen-specific immune responses, Eur. J. Immunol., 25, 596, 10.1002/eji.1830250243 van Essen, 1995, CD40 ligand-transduced costimulation of T cells in the development of helper function, Nature, 378, 620, 10.1038/378620a0 Shapira, 1991, Deletional switch recombination occurs in interleukin-4-induced isotype switching to IgE expression by human B cells, Proc. Natl Acad. Sci. USA, 147, 7528, 10.1073/pnas.88.17.7528 Zhang, 1994, Switch circles from IL-4-directed s class switching from human B lymphocytes. Evidence for direct, sequential, and multiple step sequential switch from |i to s Ig chain gene, J. Immunol., 152, 3427, 10.4049/jimmunol.152.7.3427 Kehry, 1996, CD40-mediated signaling in B cells. Balancing cell survival, growth, and death, J. Immunol., 156, 2345, 10.4049/jimmunol.156.7.2345