Bisubstrate analog probes for the insulin receptor protein tyrosine kinase: Molecular yardsticks for analyzing catalytic mechanism and inhibitor design

Bioorganic Chemistry - Tập 33 - Trang 285-297 - 2005
Aliya C. Hines1, Keykavous Parang1,2, Ronald A. Kohanski1,3, Stevan R. Hubbard4, Philip A. Cole1
1Department of Pharmacology and Molecular Sciences Johns Hopkins University School of Medicine, Baltimore, MD 21205 USA
2Department of Biomedical and Pharmaceutical Sciences, University of Rhode Island, Kingston, RI 02881, USA
3Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA
4Structural Biology Program, Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY 10016, USA

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Bioorganic Chemistry

Tập 33

285-297

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