Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure.

Journal of Clinical Investigation - Tập 88 Số 6 - Trang 2095-2105 - 1991
Masahiko Sato1, W A Grasser2,3,4,5,6,7, Naoto Endo2,3,4,5,6,7, Robert E. Akins2,3,4,5,6,7, H. T. Simmons2,3,4,5,6,7, David D. Thompson2,3,4,5,6,7, Igor E. Golub2,3,4,5,6,7, Gideon A. Rodan2,3,4,5,6,7
1Department of Bone Biology and Osteoporosis Research, Merck Sharp & Dohme Research Laboratories, West Point, Pennsylvania 19486.
2Department of Biochemistry, University of Pennsylvania,
3Department of Biology, Univer-sity of Pennsylvania, Philadelphia, PA 19104. Dr.
4Department ofBone Biology and Osteoporosis Research, Merck Sharp & Dohme Research Laboratories, West Point, Pennsylvania 19486
5Pfizer Inc., Cen-tral Research Division, Box 272, Eastern Point Road, Groton, CT 06340. Dr.
6School of Dental Medicine, 4001 Spruce Street, Al, Philadelphia, PA 19174.
7partment of Bone Biology and Osteoporosis Research, Merck Sharp & Dohme Research Laboratories, West Point, PA 19486.

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