Biosynthesis of Macrolactam BE-14106 Involves Two Distinct PKS Systems and Amino Acid Processing Enzymes for Generation of the Aminoacyl Starter Unit

Chemistry & Biology - Tập 16 - Trang 1109-1121 - 2009
Hanne Jørgensen1, Kristin F. Degnes2, Håvard Sletta2, Espen Fjærvik1, Alexander Dikiy1, Lars Herfindal3, Per Bruheim1, Geir Klinkenberg2, Harald Bredholt4, Gyrid Nygård3, Stein O. Døskeland3, Trond E. Ellingsen2, Sergey B. Zotchev1
1Department of Biotechnology, Norwegian University of Science and Technology, N-7491 Trondheim, Norway
2Department of Industrial Biotechnology, SINTEF Materials and Chemistry, SINTEF, N-7034 Trondheim, Norway
3Department of Biomedicine, University of Bergen, N-5009 Bergen, Norway
4Axellia AS, Harbitzaleen 3, 0275 Oslo, Norway

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