Bioresorbable polymers for temporary therapeutic applications

Wiley - Tập 166 Số 1 - Trang 155-168 - 1989
Michel Vert1
1UA CNRS 500 ‐ University of Rouen, LSM, INSA Rouen, BP 08, 76131 Mont‐Saint‐Aignan, France

Tóm tắt

AbstractPolymer science is mature enough to allow one to think about tailor‐making macromolecular compounds aimed at interacting purposely with living systems. Reasons for developing bioresorbable polymers for temporary therapeutic applications are discussed with respect to property adjustments and economical factors. The field of the applications is first described and guidelines for tailor‐making multimeric macromolecules with desired properties are presented. The approach led to focuss investigations on poly(α‐hydroxy acids) and functional poly(β‐hydroxy acids) derived from natural hydroxy acids, namely lactic, glycolic and malic acids. Physical, mechanical and biological properties of some corresponding polymers and copolymers are presented. Last but not least, examples of applications currently investigated are recalled.

Từ khóa


Tài liệu tham khảo

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Thông tin xuất bản

Wiley

Tập 166 Số 1

155-168

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