Biopsychosocial risk factors for pain and pain-related disability 1 year after surgery for breast cancer

Springer Science and Business Media LLC - Tập 30 - Trang 4465-4475 - 2022
Lore Dams1,2,3, Elien Van der Gucht4,3, Vincent Haenen1,2,3, Magalie Lauwers1, Sofie De Pauw1, Tinne Steurs1, Nele Devoogdt2,5, Ann Smeets6, Koen Bernar7, Tessa De Vrieze1,2, An De Groef1,4,3, Mira Meeus1,3,8
1Faculty of Medicine and Health Sciences, Department of Rehabilitation Sciences and Physiotherapy, MOVANT, University of Antwerp, Antwerp, Belgium
2Department of Rehabilitation Sciences, KU Leuven, University of Leuven, Leuven, Belgium
3Pain In Motion International Research Group, http://www.paininmotion.be, Brussels, Belgium
4Department of Rehabilitation Sciences, KU Leuven - University of Leuven, Leuven, Belgium
5Department of Vascular Surgery and Department of Physical Medicine and Rehabilitation, Center for Lymphedema, UZ Leuven - University Hospitals Leuven, Leuven, Belgium
6Department of Surgical Oncology, University Hospitals Leuven, Leuven, Belgium
7The Leuven Centre for Algology and Pain Management, University Hospitals Leuven, Leuven, Belgium
8Faculty of Medicine and Health Sciences, Department of Rehabilitation Sciences and Physiotherapy, Ghent University, Ghent, Belgium

Tóm tắt

Knowledge regarding risk factors for pain in the long term after surgery for breast cancer may be of great value in preventing this prevalent and debilitating side effect. Despite the biopsychosocial nature of pain, the predictive value of both pre- and postoperative biopsychosocial functioning for long-term pain intensity and pain-related disability has not yet been studied. One hundred sixty-six women planned for unilateral breast cancer surgery were included in this prospective cohort study. Pre- and postoperative outcomes related to pain, psychosocial, and somatosensory functioning (questionnaires and quantitative sensory testing) were evaluated as risk factors for pain intensity (visual analog scale) and pain-related disability (pain disability index) 1 year after surgery for breast cancer. Both bivariable and stepwise linear regression analyses were performed. The most consistent biopsychosocial risk factors were symptoms related to altered central somatosensory functioning (central sensitization inventory), psychological symptoms, and social support (psychological symptoms and support subscale of McGill Quality of Life Questionnaire). Results also showed that a pre- and postoperative disturbed functioning of the somatosensory nervous system in the surgical area could provide additional information regarding pain intensity or pain-related disability in the long term after surgery for breast cancer. This study revealed several biopsychosocial characteristics that might be used to identify women more vulnerable to have pain and pain-related disability in the long term after surgery for breast cancer, allowing for more effective pain management and prevention.

Tài liệu tham khảo

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