Biophotonics and Biotechnology in Pancreatic Cancer: Cyclic RGD-Peptide-Conjugated Type II Quantum Dots for in vivo Imaging

Yeo, 2004, Pancreatic cancer, Curr Prob Cancer, 26, 176, 10.1067/mcn.2002.129579 Hingorani, 2003, Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse, Cancer Cell, 4, 437, 10.1016/S1535-6108(03)00309-X Hruban, 2007, Precursors to pancreatic cancer, Gastroenterol Clin N Am, 36, 831, 10.1016/j.gtc.2007.08.012 Swierczynski, 2004, Analysis of novel tumor markers in pancreatic and biliary carcinomas using tissue microarrays, Hum Pathol, 35, 357, 10.1016/j.humpath.2003.10.012 Cao, 2006, Combination of integrin sirna and irradiation for breast cancer therapy, Biochem Biophys Res Commun, 351, 726, 10.1016/j.bbrc.2006.10.100 Psimadas, 2006, Study of the labeling of two novel RGD-peptidic derivatives with the precursor [99mtc(H2O)3(CO)3]+ and evaluation for early angiogenesis detection in cancer, Appl Radiat Isotopes, 64, 151, 10.1016/j.apradiso.2005.06.010 Cai, 2008, vol 45, 141 Chen, 2004, Pharmacokinetics and tumor retention of 125I-labeled RGD peptide are improved by pegylation, Nucl Med Biol, 31, 11, 10.1016/j.nucmedbio.2003.07.003 Dobrucki, 2007, Imaging angiogenesis, Curr Opin Biotechnol, 18, 90, 10.1016/j.copbio.2007.01.005 Chen, 2004, 18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis, Nucl Med Biol, 31, 179, 10.1016/j.nucmedbio.2003.10.002 Juzenas, 2008, Quantum dots and nanoparticles for photodynamic and radiation therapies of cancer, Adv Drug Deliv Rev, 60, 1600, 10.1016/j.addr.2008.08.004 Li, 2008, Glutathione-mediated release of functional plasmid DNA from positively charged quantum dots, Biomaterials, 29, 2776, 10.1016/j.biomaterials.2008.03.007 Yu, 2006, Water-soluble quantum dots for biomedical applications, Biochem Biophys Res Commun, 348, 781, 10.1016/j.bbrc.2006.07.160 Azzazy, 2007, From diagnostics to therapy: prospects of quantum dots, Clin Biochem, 40, 917, 10.1016/j.clinbiochem.2007.05.018 Hild, 2008, Quantum dots — nano-sized probes for the exploration of cellular and intracellular targeting, Eur J Pharmaceut Biopharmaceut, 68, 153, 10.1016/j.ejpb.2007.06.009 Santos, 2008, 773 Yong, 2006, Growth of CDSE quantum rods and multipods seeded by noble metal nanoparticles, Adv Mater, 18, 1978, 10.1002/adma.200600368 Dubertret, 2002, In vivo imaging of quantum dots encapsulated in phospholipid micelles, Science, 298, 1759, 10.1126/science.1077194 Pan, 2009, Targeting and imaging cancer cells by folate-decorated, quantum dots (QDs)-loaded nanoparticles of biodegradable polymers, Biomaterials, 30, 1176, 10.1016/j.biomaterials.2008.10.039 Yong, 2007, Quantum rod bioconjugates as targeted probes for confocal and two-photon fluorescence imaging of cancer cells, Nano Lett, 7, 761, 10.1021/nl063031m Yong, 2008, Multiplex imaging of pancreatic cancer cells by using functionalized quantum rods, Adv Materials, 20, 1412, 10.1002/adma.200702462 Sanvicens, 2008, Multifunctional nanoparticles — properties and prospects for their use in human medicine, Trends Biotechnol, 26, 425, 10.1016/j.tibtech.2008.04.005 Terai, 2008, Fluorescent probes for bioimaging applications, Curr Opin Chem Biol, 12, 515, 10.1016/j.cbpa.2008.08.007 Wang, 2009, QD as a bifunctional cell-surface marker for both fluorescence and atomic force microscopy, Ultramicroscopy, 109, 268, 10.1016/j.ultramic.2008.11.020 Tan, 2007, Ultrafine biocompatible chitosan nanoparticles encapsulating multi-coloured quantum dots for bio-applications, J Colloid Interface Sci, 310, 464, 10.1016/j.jcis.2007.01.083 Smith, 2008, Bio-conjugated quantum dots for in vivo molecular and cellular imaging, Adv Drug Deliv Rev, 60, 1226, 10.1016/j.addr.2008.03.015 Prasad, 2004 Choi, 2007, Renal clearance of quantum dots, Nat Biotech, 25, 1165, 10.1038/nbt1340 Wang, 2007, Application of ultrasonic irradiation in aqueous synthesis of highly fluorescent CdTe/CdS core-shell nanocrystals, J Phys Chem C, 111, 2465, 10.1021/jp066601f Schreder, 2000, CdTe/CdS clusters with ‘core-shell’ structure in colloids and films: the path of formation and thermal breakup, J Phys Chem B, 104, 1677, 10.1021/jp991468v Schöps, 2006, Recombination dynamics of CdTe/CdS core-shell nanocrystals, J Phys Chem B, 110, 2074, 10.1021/jp0557013 Bao, 2004, Enhancement effect of illumination on the photoluminescence of water-soluble CDTE nano crystals: toward highly fluorescent CdTe/CdS core-shell structure, Chem Materials, 16, 3853, 10.1021/cm049172b He, 2006, Microwave-assisted growth and characterization of water-dispersed CdTe/CdS core-shell nanocrystals with high photoluminescence, J Phys Chem B, 110, 13370, 10.1021/jp057498h Yang L, Mao H, Cao Z, Wang YA, Peng X, Wang X, Sajja HK, Wang L, Duan H, Ni C, Staley CA, Wood WC, Gao X, Nie S; Molecular imaging of pancreatic cancer in a preclinical animal tumor model using targeted multifunctional nanoparticles. Gastroenterology. In press, uncorrected proof. Cho, 2007, Long-term exposure to cdte quantum dots causes functional impairments in live cells, Langmuir, 23, 1974, 10.1021/la060093j Gao, 2004, In vivo cancer targeting and imaging with semiconductor quantum dots, Nat Biotech, 22, 969, 10.1038/nbt994 Cai, 2006, Peptide-labeled near-infrared quantum dots for imaging tumor vasculature in living subjects, Nano Lett, 6, 669, 10.1021/nl052405t Chen, 2008, Bio-distribution and metabolic paths of silica coated CDSEs quantum dots, Toxicol Appl Pharmacol, 230, 364, 10.1016/j.taap.2008.03.022 Gao, 2008, Quantum dots bearing lectin-functionalized nanoparticles as a platform for in vivo brain imaging, Bioconjugate Chem, 19, 2189, 10.1021/bc8002698 Ballou, 2004, Noninvasive imaging of quantum dots in mice, Bioconjugate Chem, 15, 79, 10.1021/bc034153y Ballou, 2007, Sentinel lymph node imaging using quantum dots in mouse tumor models, Bioconjugate Chem, 18, 389, 10.1021/bc060261j Li, 2009, In vitro cancer cell imaging and therapy using transferrin-conjugated gold nanoparticles, Cancer Lett, 274, 319, 10.1016/j.canlet.2008.09.024 Papagiannaros A, Levchenko T, Hartner W, Mongayt D, Torchilin V; Quantum dots encapsulated in phospholipid micelles for imaging and quantification of tumors in the near-infrared region. Nanomed Nanotechnol Biol Med. In press, corrected proof. Zhang, 2009, Influence of anchoring ligands and particle size on the colloidal stability and in vivo biodistribution of polyethylene glycol-coated gold nanoparticles in tumor-xenografted mice, Biomaterials, 30, 1928, 10.1016/j.biomaterials.2008.12.038 Zhang, 2007, Preparation and characterization of 99mtc(co)3-bpy-RGD complex as [alpha]v[beta]3 integrin receptor-targeted imaging agent, Appl Radiat Isotopes, 65, 70, 10.1016/j.apradiso.2006.07.013 Kennel, 2008, The fate of mab-targeted cd125mte/zns nanoparticles in vivo, Nucl Med Biol, 35, 501, 10.1016/j.nucmedbio.2008.02.001 Maysinger, 2007, Fate of micelles and quantum dots in cells, Eur J Pharmaceut Biopharmaceut, 65, 270, 10.1016/j.ejpb.2006.08.011 Su, 2009, The cytotoxicity of cadmium based, aqueous phase — synthesized, quantum dots and its modulation by surface coating, Biomaterials, 30, 19, 10.1016/j.biomaterials.2008.09.029 Erogbogbo, 2008, Biocompatible luminescent silicon quantum dots for imaging of cancer cells, ACS Nano, 2, 873, 10.1021/nn700319z