Biomimetic nanoengineered scaffold for enhanced full-thickness cutaneous wound healing

Dussoyer, 2020, Decellularized Scaffolds for Skin Repair and Regeneration, Appl. Sci., 10, 3435, 10.3390/app10103435 Zielins, 2014, Wound healing: an update, Regenerative medicine, 9, 817, 10.2217/rme.14.54 Gurtner, 2008, Wound repair and regeneration, Nature, 453, 314, 10.1038/nature07039 Liang, 2019, Adhesive Hemostatic Conducting Injectable Composite Hydrogels with Sustained Drug Release and Photothermal Antibacterial Activity to Promote Full-Thickness Skin Regeneration During Wound Healing, Small, 15, 10.1002/smll.201900046 Rameshbabu, 2018, Silk sponges ornamented with a placenta-derived extracellular matrix augment full-thickness cutaneous wound healing by stimulating neovascularization and cellular migration, ACS Appl. Mater. Interfaces, 10, 16977, 10.1021/acsami.7b19007 Golchin, 2020, Effects of bilayer nanofibrillar scaffolds containing epidermal growth factor on full-thickness wound healing, Polym. Adv. Technol., 31, 2443, 10.1002/pat.4960 Yannas, 1980, Design of an artificial skin. I. Basic design principles, J. Biomed. Mater. Res., 14, 65, 10.1002/jbm.820140108 Silver, 2001, Viscoelastic properties of human skin and processed dermis, Skin Res. Technol., 7, 18, 10.1034/j.1600-0846.2001.007001018.x Mao, 2003, Structure and properties of bilayer chitosan–gelatin scaffolds, Biomaterials, 24, 1067, 10.1016/S0142-9612(02)00442-8 Wang, 2007, Evaluation and biological characterization of bilayer gelatin/chondroitin-6-sulphate/hyaluronic acid membrane, Journal of Biomedical Materials Research Part B: Applied Biomaterials: An Official Journal of The Society for Biomaterials, The Japanese Society for Biomaterials, and The Australian Society for Biomaterials and the Korean Society for Biomaterials, 82, 390 Zhu, 2011, Design properties of hydrogel tissue-engineering scaffolds, Expert review of medical devices, 8, 607, 10.1586/erd.11.27 Dong, 2016, Application of collagen scaffold in tissue engineering: recent advances and new perspectives, Polymers, 8, 42, 10.3390/polym8020042 De Vuyst, 2013, Reconstruction of normal and pathological human epidermis on polycarbonate filter, Epidermal Cells, Springer, 191, 10.1007/7651_2013_40 Krishnan, 2004, Design and application of a test system for viscoelastic characterization of collagen gels, Tissue Eng., 10, 241, 10.1089/107632704322791880 Beauchamp, 1992, A critical review of the toxicology of glutaraldehyde, Crit. Rev. Toxicol., 22, 143, 10.3109/10408449209145322 Yeh, 2011, A novel cell support membrane for skin tissue engineering: gelatin film cross-linked with 2-chloro-1-methylpyridinium iodide, Polymer, 52, 996, 10.1016/j.polymer.2010.10.060 Nichol, 2010, Cell-laden microengineered gelatin methacrylate hydrogels, Biomaterials, 31, 5536, 10.1016/j.biomaterials.2010.03.064 Bahney, 2011, Visible light photoinitiation of mesenchymal stem cell-laden bioresponsive hydrogels, Eur. Cells Mater., 22, 43, 10.22203/eCM.v022a04 Saghazadeh, 2018, Drug delivery systems and materials for wound healing applications, Adv. Drug. Deliv. Rev., 127, 138, 10.1016/j.addr.2018.04.008 Kokabi, 2007, PVA–clay nanocomposite hydrogels for wound dressing, Eur. Polym. J., 43, 773, 10.1016/j.eurpolymj.2006.11.030 Ruzicka, 2011, Observation of empty liquids and equilibrium gels in a colloidal clay, Nat. Mater., 10, 56, 10.1038/nmat2921 Wang, 2010, High-water-content mouldable hydrogels by mixing clay and a dendritic molecular binder, Nature, 463, 339, 10.1038/nature08693 Xavier, 2015, Bioactive nanoengineered hydrogels for bone tissue engineering: a growth-factor-free approach, ACS nano, 9, 3109, 10.1021/nn507488s Sun, 2014, Advances in skin grafting and treatment of cutaneous wounds, Science, 346, 941, 10.1126/science.1253836 Parries, 1995, The Human Urinary Epidermal Growth Factor (EGF) Precursor ISOLATION OF A BIOLOGICALLY ACTIVE 160-KILODALTON HEPARIN-BINDING PRO-EGF WITH A TRUNCATED CARBOXYL TERMINUS, J. Biol. Chem., 270, 27954, 10.1074/jbc.270.46.27954 Hardwicke, 2008, Epidermal growth factor therapy and wound healing—Past, present and future perspectives, The Surgeon, 6, 172, 10.1016/S1479-666X(08)80114-X Gorouhi, 2014, Epidermal growth factor-functionalized polymeric multilayer films: interplay between spatial location and bioavailability of EGF, J. Invest. Dermatol., 134, 1757, 10.1038/jid.2014.7 Chen, 2003, Polymeric growth factor delivery strategies for tissue engineering, Pharm. Res., 20, 1103, 10.1023/A:1025034925152 Nishida, 1988, The network structure of corneal fibroblasts in the rat as revealed by scanning electron microscopy, Invest. Ophthalmol. Vis. Sci., 29, 1887 Huang, 2015, Biomimetic LBL structured nanofibrous matrices assembled by chitosan/collagen for promoting wound healing, Biomaterials, 53, 58, 10.1016/j.biomaterials.2015.02.076 Siimon, 2015, Mechanical characterization of electrospun gelatin scaffolds cross-linked by glucose, J. Mater. Sci. Mater. Med., 26, 37, 10.1007/s10856-014-5375-1 Jafari, 2020, Bioactive antibacterial bilayer PCL/gelatin nanofibrous scaffold promotes full-thickness wound healing, Int. J. Pharm., 10.1016/j.ijpharm.2020.119413 Ghafari, 2019, Fabrication and characterization of novel bilayer scaffold from nanocellulose based aerogel for skin tissue engineering applications, Int. J. Biol. Macromol., 136, 796, 10.1016/j.ijbiomac.2019.06.104 Kamali, 2020, Fabrication and evaluation of a bilayer hydrogel-electrospinning scaffold prepared by the freeze-gelation method, J. Biomech., 98, 10.1016/j.jbiomech.2019.109466 Miraftab, 2015, Physical stabilisation of electrospun poly (vinyl alcohol) nanofibres: comparative study on methanol and heat-based crosslinking, J. Mater. Sci., 50, 1943, 10.1007/s10853-014-8759-1 Bunn, 1981, Reaction of monosaccharides with proteins: possible evolutionary significance, Science, 213, 222, 10.1126/science.12192669 Zandi, 2020, Core-sheath gelatin based electrospun nanofibers for dual delivery release of biomolecules and therapeutics, Mater. Sci. Eng.: C, 108, 10.1016/j.msec.2019.110432 Lin, 2012, Preparation and surface activities of modified gelatin–glucose conjugates, Colloids Surf. A, 408, 97, 10.1016/j.colsurfa.2012.05.036 Nguyen, 2010, Fabrication and characterization of cross-linked gelatin electro-spun nano-fibers, J. Biomed. Sci. Eng., 3, 1117, 10.4236/jbise.2010.312145 Paul, 2016, Nanoengineered biomimetic hydrogels for guiding human stem cell osteogenesis in three dimensional microenvironments, J. Mater. Chem. B., 4, 3544, 10.1039/C5TB02745D Modaresifar, 2018, Design and fabrication of GelMA/chitosan nanoparticles composite hydrogel for angiogenic growth factor delivery, Artificial cells, Nanomedicine, and Biotechnology, 46, 1799 Yue, 2015, Synthesis, properties, and biomedical applications of gelatin methacryloyl (GelMA) hydrogels, Biomaterials, 73, 254, 10.1016/j.biomaterials.2015.08.045 Annabi, 2017, Engineering a sprayable and elastic hydrogel adhesive with antimicrobial properties for wound healing, Biomaterials, 139, 229, 10.1016/j.biomaterials.2017.05.011 Liu, 2010, A biomimetic hydrogel based on methacrylated dextran-graft-lysine and gelatin for 3D smooth muscle cell culture, Biomaterials, 31, 1158, 10.1016/j.biomaterials.2009.10.040 Van den Steen, 2002, Biochemistry and molecular biology of gelatinase B or matrix metalloproteinase-9 (MMP-9), Crit. Rev. Biochem. Mol. Biol., 37, 375, 10.1080/10409230290771546 Tondera, 2016, Gelatin-based hydrogel degradation and tissue interaction in vivo: insights from multimodal preclinical imaging in immunocompetent nude mice, Theranostics, 6, 2114, 10.7150/thno.16614 Sani, 2019, An antimicrobial dental light curable bioadhesive hydrogel for treatment of peri-implant diseases, Matter, 1, 926, 10.1016/j.matt.2019.07.019 Yang, 2014, Cellulose nanocrystals mechanical reinforcement in composite hydrogels with multiple cross-links: correlations between dissipation properties and deformation mechanisms, Macromolecules, 47, 4077, 10.1021/ma500729q Trappmann, 2012, Extracellular-matrix tethering regulates stem-cell fate, Nat. Mater., 11, 642, 10.1038/nmat3339 Shin, 2013, Carbon-nanotube-embedded hydrogel sheets for engineering cardiac constructs and bioactuators, ACS Nano, 7, 2369, 10.1021/nn305559j Shin, 2013, Cell-laden microengineered and mechanically tunable hybrid hydrogels of gelatin and graphene oxide, Adv. Mater., 25, 6385, 10.1002/adma.201301082 Li, 2011, Determining elastic properties of skin by measuring surface waves from an impulse mechanical stimulus using phase-sensitive optical coherence tomography, J. R. Soc., Interface, 9, 831, 10.1098/rsif.2011.0583 Yang, 2010, A green fabrication approach of gelatin/CM-chitosan hybrid hydrogel for wound healing, Carbohydr. Polym., 82, 1297, 10.1016/j.carbpol.2010.07.013 Zhao, 2016, Photocrosslinkable gelatin hydrogel for epidermal tissue engineering, Adv. Healthc. Mater, 5, 108, 10.1002/adhm.201500005 Ghobril, 2015, The chemistry and engineering of polymeric hydrogel adhesives for wound closure: a tutorial, Chem. Soc. Rev., 44, 1820, 10.1039/C4CS00332B Gaharwar, 2014, Nanocomposite hydrogels for biomedical applications, Biotechnol. Bioeng., 111, 441, 10.1002/bit.25160 Avery, 2016, An injectable shear-thinning biomaterial for endovascular embolization, Sci. Transl. Med., 8, 365ra156, 10.1126/scitranslmed.aah5533 Gaharwar, 2014, Shear-thinning nanocomposite hydrogels for the treatment of hemorrhage, ACS Nano, 8, 9833, 10.1021/nn503719n Roger, 2007, Hemostasis and hemostatic agents in minimally invasive surgery, Surgery, 142, S39, 10.1016/j.surg.2007.06.023 Ostomel, 2007, Metal oxide surface charge mediated hemostasis, Langmuir, 23, 11233, 10.1021/la701281t Duarte, 2012, Surgical adhesives: systematic review of the main types and development forecast, Prog. Polym. Sci., 37, 1031, 10.1016/j.progpolymsci.2011.12.003 Sierra, 1992, A method to determine shear adhesive strength of fibrin sealants, J. Appl. Biomater., 3, 147, 10.1002/jab.770030210 Rajabi, 2020, An adhesive and injectable nanocomposite hydrogel of thiolated gelatin/gelatin methacrylate/Laponite® as a potential surgical sealant, J. Colloid Interface Sci., 564, 155, 10.1016/j.jcis.2019.12.048 Lang, 2014, A blood-resistant surgical glue for minimally invasive repair of vessels and heart defects, Sci. Transl. Med., 6, 218ra6, 10.1126/scitranslmed.3006557 Yao, 2010, Phototoxicity is not associated with photochemical tissue bonding of skin, Lasers in Surgery and Medicine: The Official Journal of the American Society for Laser Medicine and Surgery, 42, 123, 10.1002/lsm.20869 Smart, 2005, The basics and underlying mechanisms of mucoadhesion, Adv. Drug. Deliv. Rev., 57, 1556, 10.1016/j.addr.2005.07.001 Buckley, 1985, Sustained release of epidermal growth factor accelerates wound repair, Proc. Natl. Acad. Sci., 82, 7340, 10.1073/pnas.82.21.7340 Lashinger, 2014, Interacting inflammatory and growth factor signals underlie the obesity-cancer link, J. Nutr., 144, 109, 10.3945/jn.113.178533 Ritger, 1987, A simple equation for description of solute release II. Fickian and anomalous release from swellable devices, J. Control. Release, 5, 37, 10.1016/0168-3659(87)90035-6 Ding, 2016, A shear-thinning hydrogel that extends in vivo bioactivity of FGF2, Biomaterials, 111, 80, 10.1016/j.biomaterials.2016.09.026 Dawson, 2011, Clay gels for the delivery of regenerative microenvironments, Adv. Mater., 23, 3304, 10.1002/adma.201100968 Wang, 2012, Effect of mitomycin on normal dermal fibroblast and HaCat cell: an in vitro study, Journal of Zhejiang University SCIENCE B, 13, 997, 10.1631/jzus.B1200055 Guerreiro, 2012, Implanted neonatal human dermal fibroblasts influence the recruitment of endothelial cells in mice, Biomatter, 2, 43, 10.4161/biom.20063 Grayson, 2008, Effects of initial seeding density and fluid perfusion rate on formation of tissue-engineered bone, Tissue Eng. Part A, 14, 1809, 10.1089/ten.tea.2007.0255 Divieto, 2015, A first approach to evaluate the cell dose in highly porous scaffolds by using a nondestructive metabolic method, Future science OA, 1, 10.4155/fso.15.58 Turner, 1978, Effects of glucose and sorbitol on proliferation of cultured human skin fibroblasts and arterial smooth-muscle cells, Diabetes, 27, 583, 10.2337/diab.27.5.583 Sarker, 2014, Evaluation of fibroblasts adhesion and proliferation on alginate-gelatin crosslinked hydrogel, PLoS One, 9, 10.1371/journal.pone.0107952 Dawson, 2013, Clay: new opportunities for tissue regeneration and biomaterial design, Adv. Mater., 25, 4069, 10.1002/adma.201301034 Singer, 1999, Cutaneous wound healing, N. Engl. J. Med., 341, 738, 10.1056/NEJM199909023411006 Sundaramurthi, 2014, Electrospun nanofibers as scaffolds for skin tissue engineering, Polym. Rev., 54, 348, 10.1080/15583724.2014.881374 Goh, 2016, Epidermal growth factor loaded heparin-based hydrogel sheet for skin wound healing, Carbohydr. Polym., 147, 251, 10.1016/j.carbpol.2016.03.072 Choi, 2008, In vivo wound healing of diabetic ulcers using electrospun nanofibers immobilized with human epidermal growth factor (EGF), Biomaterials, 29, 587, 10.1016/j.biomaterials.2007.10.012 Lokhande, 2018, Nanoengineered injectable hydrogels for wound healing application, Acta Biomater., 70, 35, 10.1016/j.actbio.2018.01.045 Maver, 2015, Functional wound dressing materials with highly tunable drug release properties, RSC Adv., 5, 77873, 10.1039/C5RA11972C Gonzalez, 2016, Wound healing-A literature review, An. Bras. Dermatol., 91, 614, 10.1590/abd1806-4841.20164741