Biomechanics of Concussion

Clinics in Sports Medicine - Tập 30 Số 1 - Trang 19-31 - 2011
David F. Meaney1, Douglas H. Smith2
1Department of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 South 33rd Street, Philadelphia, PA 19104-6392, USA.
2Department of Neurosurgery, University of Pennsylvania, 105D Hayden Hall, 240 South 33rd Street, Philadelphia, PA 19104-6392, USA

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Bazarian, 2005, Mild traumatic brain injury in the United States, 1998–2000, Brain Inj, 19, 85, 10.1080/02699050410001720158

Langlois, 2006, The epidemiology and impact of traumatic brain injury: a brief overview, J Head Trauma Rehabil, 21, 375, 10.1097/00001199-200609000-00001

Eibner, 2009, Care of war veterans with mild traumatic brain injury, N Engl J Med, 361, 537

Preiss-Farzanegan, 2009, The relationship between gender and postconcussion symptoms after sport-related mild traumatic brain injury, PM R, 1, 245, 10.1016/j.pmrj.2009.01.011

Xydakis, 2008, Mild traumatic brain injury in U.S. soldiers returning from Iraq, N Engl J Med, 358, 2177, 10.1056/NEJMc086083

McElhaney, 1995, Mechanisms of basilar skull fracture, J Neurotrauma, 12, 669, 10.1089/neu.1995.12.669

Shreiber, 1999, Immediate in vivo response of the cortex and the blood-brain barrier following dynamic cortical deformation in the rat, Neurosci Lett, 259, 5, 10.1016/S0304-3940(98)00853-2

Raymond, 2009, Tolerance of the skull to blunt ballistic temporo-parietal impact, J Biomech, 42, 2479, 10.1016/j.jbiomech.2009.07.018

Yoganandan, 2004, Biomechanics of temporo-parietal skull fracture, Clin Biomech (Bristol, Avon), 19, 225, 10.1016/j.clinbiomech.2003.12.014

Graham, 1995, The nature, distribution and causes of traumatic brain injury, Brain Pathol, 5, 397, 10.1111/j.1750-3639.1995.tb00618.x

Adams, 1985, The contusion index: a reappraisal in human and experimental non-missile head injury, Neuropathol Appl Neurobiol, 11, 299, 10.1111/j.1365-2990.1985.tb00027.x

Gurdjian, 1961, Intracranial pressure and acceleration accompanying head impacts in human cadavers, Surg Gynecol Obstet, 113, 185

Thomas, 1966, Experimental intracranial pressure gradients in the human skull, J Neurol Neurosurg Psychiatr, 29, 404, 10.1136/jnnp.29.5.404

Lindgren, 1966, Experimental studies in head injury. II. Pressure propagation in “percussion concussion”, Biophysik, 3, 174, 10.1007/BF01191611

Gurdjian, 1954, Studies on experimental concussion: relation of physiologic effect to time duration of intracranial pressure increase at impact, Neurology, 4, 674, 10.1212/WNL.4.9.674

Denny-Brown, 1941, Experimental concussion: (section of neurology), Proc R Soc Med, 34, 691

Gurdjian, 1950, The mechanism of skull fracture, J Neurosurg, 7, 106, 10.3171/jns.1950.7.2.0106

Gurdjian, 1949, Studies on skull fracture with particular reference to engineering factors, Am J Surg, 78, 736, 10.1016/0002-9610(49)90315-3

Gurdjian, 1947, The mechanism of production of linear skull fracture; further studies on deformation of the skull by the stresscoat technique, Surg Gynecol Obstet, 85, 195

Takhounts, 2003, On the importance of nonlinearity of brain tissue under large deformations, Stapp Car Crash J, 47, 79

Miller, 1997, Constitutive modelling of brain tissue: experiment and theory, J Biomech, 30, 1115, 10.1016/S0021-9290(97)00092-4

Donnelly, 1997, Shear properties of human brain tissue, J Biomech Eng, 119, 423, 10.1115/1.2798289

Arbogast, 1997, A high-frequency shear device for testing soft biological tissues, J Biomech, 30, 757, 10.1016/S0021-9290(97)00023-7

Prange, 2000, Defining brain mechanical properties: effects of region, direction, and species, Stapp Car Crash J, 44, 205

Unterharnscheidt, 1969, Traumatic lesions of brain and spinal cord due to nondeforming angular acceleration of the head, Tex Rep Biol Med, 27, 127

Gennarelli, 1982, Diffuse axonal injury and traumatic coma in the primate, Ann Neurol, 12, 564, 10.1002/ana.410120611

Adams, 1982, Diffuse axonal injury due to nonmissile head injury in humans: an analysis of 45 cases, Ann Neurol, 12, 557, 10.1002/ana.410120610

Ommaya, 1974, Cerebral concussion and traumatic unconsciousness. Correlation of experimental and clinical observations of blunt head injuries, Brain, 97, 633, 10.1093/brain/97.1.633

Nahum AM, Smith R, Ward CC. Intracranial pressure dynamics during head impact. in 21st Annual Stapp Car Crash Conference. 1977: Society of Automotive Engineers.

Stalhammar, 1975, Experimental brain damage from fluid pressures due to impact acceleration, Acta Neurol Scand, 52, 38, 10.1111/j.1600-0404.1975.tb02826.x

Takhounts, 2008, Investigation of traumatic brain injuries using the next generation of simulated injury monitor (SIMon) finite element head model, Stapp Car Crash J, 52, 1

Ishikawa, 2006, Finite element analysis and experimental study on mechanism of brain injury using brain model, Conf Proc IEEE Eng Med Biol Soc, 1, 1327, 10.1109/IEMBS.2006.259665

Bell, 2007, Mild in vitro trauma induces rapid Glur2 endocytosis, robustly augments calcium permeability and enhances susceptibility to secondary excitotoxic insult in cultured Purkinje cells, Brain, 130, 2528, 10.1093/brain/awm164

Franklyn, 2005, Analysis of finite element models for head injury investigation: reconstruction of four real-world impacts, Stapp Car Crash J, 49, 1

Zhang, 2001, Recent advances in brain injury research: a new human head model development and validation, Stapp Car Crash J, 45, 369

Zhang, 2002, Computational study of the contribution of the vasculature on the dynamic response of the brain, Stapp Car Crash J, 46, 145

Thibault, 1992, Biomechanical aspects of a fluid percussion model of brain injury, J Neurotrauma, 9, 311, 10.1089/neu.1992.9.311

Smith, 2000, Immediate coma following inertial brain injury dependent on axonal damage in the brainstem, J Neurosurg, 93, 315, 10.3171/jns.2000.93.2.0315

Ivarsson, 2002, Influence of the lateral ventricles and irregular skull base on brain kinematics due to sagittal plane head rotation, J Biomech Eng, 124, 422, 10.1115/1.1485752

Ivarsson, 2000, Strain relief from the cerebral ventricles during head impact: experimental studies on natural protection of the brain, J Biomech, 33, 181, 10.1016/S0021-9290(99)00144-X

Nishimoto, 1998, Relation between diffuse axonal injury and internal head structures on blunt impact, J Biomech Eng, 120, 140, 10.1115/1.2834294

Zhang, 2004, A proposed injury threshold for mild traumatic brain injury, J Biomech Eng, 126, 226, 10.1115/1.1691446

Takahashi, 2007, 3-D finite element analysis and experimental study on brain injury mechanism, Conf Proc IEEE Eng Med Biol Soc, 2007, 3613

Li, 2007, Regional brain strains and role of falx in lateral impact-induced head rotational acceleration, Biomed Sci Instrum, 43, 24

Zhang, 2006, Role of translational and rotational accelerations on brain strain in lateral head impact, Biomed Sci Instrum, 42, 501

Zhang, 2001, Comparison of brain responses between frontal and lateral impacts by finite element modeling, J Neurotrauma, 18, 21, 10.1089/089771501750055749

Miller, 2009, Mechanically induced reactive gliosis causes ATP-mediated alterations in astrocyte stiffness, J Neurotrauma, 26, 789, 10.1089/neu.2008.0727

Charles, 1991, Intercellular signaling in glial cells: calcium waves and oscillations in response to mechanical stimulation and glutamate, Neuron, 6, 983, 10.1016/0896-6273(91)90238-U

Di, 2000, Mechanical injury alters volume activated ion channels in cortical astrocytes, Acta Neurochir Suppl, 76, 379, 10.1007/978-3-7091-6346-7_79

Floyd, 2001, Traumatic injury of cultured astrocytes alters inositol (1,4,5)-trisphosphate-mediated signaling, Glia, 33, 12, 10.1002/1098-1136(20010101)33:1<12::AID-GLIA1002>3.0.CO;2-V

Hoffman, 2000, Astrocytes generate isoprostanes in response to trauma or oxygen radicals, J Neurotrauma, 17, 415, 10.1089/neu.2000.17.415

Ahmed, 2000, Stretch-induced injury alters mitochondrial membrane potential and cellular ATP in cultured astrocytes and neurons, J Neurochem, 74, 1951, 10.1046/j.1471-4159.2000.0741951.x

Rzigalinski, 1999, Calcium influx factor, further evidence it is 5, 6-epoxyeicosatrienoic acid, J Biol Chem, 274, 175, 10.1074/jbc.274.1.175

Lamb, 1997, Alterations in phosphatidylcholine metabolism of stretch-injured cultured rat astrocytes, J Neurochem, 68, 1904, 10.1046/j.1471-4159.1997.68051904.x

Zhang, 1996, Reduction of voltage-dependent Mg2+ blockade of NMDA current in mechanically injured neurons, Science, 274, 1921, 10.1126/science.274.5294.1921

Kao, 2004, Potentiation of GABA(A) currents after mechanical injury of cortical neurons, J Neurotrauma, 21, 259, 10.1089/089771504322972059

Spaethling, 2008, Calcium-permeable AMPA receptors appear in cortical neurons after traumatic mechanical injury and contribute to neuronal fate, J Neurotrauma, 25, 1207, 10.1089/neu.2008.0532

Bell, 2009, PICK1-mediated GluR2 endocytosis contributes to cellular injury after neuronal trauma, Cell Death Differ, 16, 1665, 10.1038/cdd.2009.106

Cui, 2007, PDZ protein interactions underlying NMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors, J Neurosci, 27, 9901, 10.1523/JNEUROSCI.1464-07.2007

Aarts, 2002, Treatment of ischemic brain damage by perturbing NMDA receptor- PSD-95 protein interactions, Science, 298, 846, 10.1126/science.1072873

Sattler, 1999, Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein, Science, 284, 1845, 10.1126/science.284.5421.1845

Weber, 1999, Alterations in calcium-mediated signal transduction after traumatic injury of cortical neurons, Cell Calcium, 26, 289, 10.1054/ceca.1999.0082

LaPlaca, 2005, High rate shear strain of three-dimensional neural cell cultures: a new in vitro traumatic brain injury model, J Biomech, 38, 1093, 10.1016/j.jbiomech.2004.05.032

Geddes, 2003, Mechanical stretch to neurons results in a strain rate and magnitude-dependent increase in plasma membrane permeability, J Neurotrauma, 20, 1039, 10.1089/089771503770195885

Geddes, 2003, Susceptibility of hippocampal neurons to mechanically induced injury, Exp Neurol, 184, 420, 10.1016/S0014-4886(03)00254-1

Geddes-Klein, 2006, Mechanisms and consequences of neuronal stretch injury in vitro differ with the model of trauma, J Neurotrauma, 23, 193, 10.1089/neu.2006.23.193

Lucas, 1987, Proximal segment retraction increases the probability of nerve cell survival after dendrite transection, Brain Res, 425, 384, 10.1016/0006-8993(87)90526-9

Lucas, 1985, Neuronal survival or death after dendrite transection close to the perikaryon: correlation with electrophysiologic, morphologic, and ultrastructural changes, Cent Nerv Syst Trauma, 2, 231, 10.1089/cns.1985.2.231

Wolf, 2001, Traumatic axonal injury induces calcium influx modulated by tetrodotoxin-sensitive sodium channels, J Neurosci, 21, 1923, 10.1523/JNEUROSCI.21-06-01923.2001

Smith, 1999, High tolerance and delayed elastic response of cultured axons to dynamic stretch injury, J Neurosci, 19, 4263, 10.1523/JNEUROSCI.19-11-04263.1999

von Reyn, 2009, Calpain mediates proteolysis of the voltage-gated sodium channel alpha-subunit, J Neurosci, 29, 10350, 10.1523/JNEUROSCI.2339-09.2009

Iwata, 2004, Traumatic axonal injury induces proteolytic cleavage of the voltage-gated sodium channels modulated by tetrodotoxin and protease inhibitors, J Neurosci, 24, 4605, 10.1523/JNEUROSCI.0515-03.2004

Morrison, 2003, A tissue level tolerance criterion for living brain developed with an in vitro model of traumatic mechanical loading, Stapp Car Crash J, 47, 93

Morrison, 2000, Dynamic mechanical stretch of organotypic brain slice cultures induces differential genomic expression: relationship to mechanical parameters, J Biomech Eng, 122, 224, 10.1115/1.429650

Morrison, 2000, Traumatic injury induces differential expression of cell death genes in organotypic brain slice cultures determined by complementary DNA array hybridization, Neuroscience, 96, 131, 10.1016/S0306-4522(99)00537-0

Elkin, 2007, Region-specific tolerance criteria for the living brain, Stapp Car Crash J, 51, 127

Cater, 2006, Temporal development of hippocampal cell death is dependent on tissue strain but not strain rate, J Biomech, 39, 2810, 10.1016/j.jbiomech.2005.09.023

Morrison, 2006, An in vitro model of traumatic brain injury utilising two-dimensional stretch of organotypic hippocampal slice cultures, J Neurosci Methods, 150, 192, 10.1016/j.jneumeth.2005.06.014

DeRidder, 2006, Traumatic mechanical injury to the hippocampus in vitro causes regional caspase-3 and calpain activation that is influenced by NMDA receptor subunit composition, Neurobiol Dis, 22, 165, 10.1016/j.nbd.2005.10.011

Yu, 2009, Quantification of functional alterations after in vitro traumatic brain injury, Conf Proc IEEE Eng Med Biol Soc, 2009, 1135

Yu, 2009, Neural sensing of electrical activity with stretchable microelectrode arrays, Conf Proc IEEE Eng Med Biol Soc, 2009, 4210

Yu, 2010, Experimental mild traumatic brain injury induces functional alteration of the developing hippocampus, J Neurophysiol, 103, 499, 10.1152/jn.00775.2009

Yu, 2009, Monitoring hippocampus electrical activity in vitro on an elastically deformable microelectrode array, J Neurotrauma, 26, 1135, 10.1089/neu.2008.0810

Murphy, 1993, A model for compression trauma: pressure-induced injury in cell cultures, J Neurotrauma, 10, 431, 10.1089/neu.1993.10.431

Panizzon, 1998, Neuroprotection with Bcl-2(20-34) peptide against trauma, Neuroreport, 9, 4131, 10.1097/00001756-199812210-00024

Girard, 1996, Azelastine protects against CA1 traumatic neuronal injury in the hippocampal slice, Eur J Pharmacol, 300, 43, 10.1016/0014-2999(95)00804-7

Wallis, 1996, Traumatic neuroprotection with inhibitors of nitric oxide and ADP-ribosylation, Brain Res, 710, 169, 10.1016/0006-8993(95)01278-8

Panizzon, 1996, Neuroprotection against CA1 injury with metalloporphyrins, Neuroreport, 7, 662, 10.1097/00001756-199601310-00067

Wallis, 1995, Felbamate neuroprotection against CA1 traumatic neuronal injury, Eur J Pharmacol, 294, 475, 10.1016/0014-2999(95)00568-4

Lucas, 1991, In vitro studies of multiple impact injury to mammalian CNS neurons: prevention of perikaryal damage and death by ketamine, Brain Res, 543, 181, 10.1016/0006-8993(91)90027-S

Kiraly, 2007, Traumatic brain injury and delayed sequelae: a review—traumatic brain injury and mild traumatic brain injury (concussion) are precursors to later-onset brain disorders, including early-onset dementia, ScientificWorldJournal, 7, 1768, 10.1100/tsw.2007.269

Guskiewicz, 2005, Association between recurrent concussion and late-life cognitive impairment in retired professional football players, Neurosurgery, 57, 719, 10.1227/01.NEU.0000175725.75780.DD

Stern, 1991, Head trauma as a risk factor for Parkinson’s disease, Mov Disord, 6, 95, 10.1002/mds.870060202

Viano, 2007, Concussion in professional football: biomechanics of the struck player–part 14, Neurosurgery, 61, 313, 10.1227/01.NEU.0000279969.02685.D0

Pellman, 2003, Concussion in professional football: location and direction of helmet impacts-Part 2, Neurosurgery, 53, 1328, 10.1227/01.NEU.0000093499.20604.21

Manoogian, 2006, Head acceleration is less than 10 percent of helmet acceleration in football impacts, Biomed Sci Instrum, 42, 383

Brolinson, 2006, Analysis of linear head accelerations from collegiate football impacts, Curr Sports Med Rep, 5, 23, 10.1097/01.CSMR.0000306515.87053.fa

Duma, 2005, Analysis of real-time head accelerations in collegiate football players, Clin J Sport Med, 15, 3, 10.1097/00042752-200501000-00002