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Định vị biomacromolecule trong tế bào vi khuẩn qua cơ chế khuếch tán và bắt giữ
Tóm tắt
Định vị subcellular của biomacromolecules ( nucleotide và protein) là cơ sở cho chức năng đúng đắn của chúng trong tế bào vi khuẩn. Một mô hình để giải thích sự định vị của biomacromolecules, đặc biệt là protein, là "khuếch tán và bắt giữ". Trong mô hình này, protein được định vị bằng cách khuếch tán qua tế bào chất hoặc màng cho đến khi gắn với một protein hoặc các protein khác đã được tích tụ trước đó trong tế bào. Việc sử dụng các sự kết hợp với protein huỳnh quang để theo dõi số phận của biomacromolecules đã mang lại cái nhìn mới về các cơ chế định vị phân tử trong tế bào sống. Ở đây, một số protein đã được trình bày theo cơ chế khuếch tán và bắt giữ để đạt đến vị trí thích hợp của chúng trong tế bào. Một số RNA cũng dường như định vị theo cơ chế này. Đây là một đặc điểm tự nhiên rằng thông tin về định vị phân tử nên tồn tại trong các chuỗi của chính protein. Tuy nhiên, rất ít thông tin đã có sẵn trong lĩnh vực này cho đến nay.
Từ khóa
#biomacromolecules #vi khuẩn #định vị #khuếch tán #bắt giữ #protein #RNATài liệu tham khảo
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