Biological evaluation of dendrimers based on melamine

Duncan, 2003, The Dawning Era of Polymer Therapeutics, Nature Drug Discovery, 2, 347, 10.1038/nrd1088 Stiriba, 2002, Dendritic Polymers in Biomedical Applications: From Potential to Clinical Use in Diagnostics and Therapy, Angew. Chem. Int. Ed, 41, 1329, 10.1002/1521-3773(20020415)41:8<1329::AID-ANIE1329>3.0.CO;2-P Esfand, 2001, Poly(amidoamine) (PAMAM) dendrimers: from biomimicry to drug delivery and biomedical applications, Drug Discov. Today, 6, 427, 10.1016/S1359-6446(01)01757-3 Patri, 2002, Dendritic polymer macromolecular carriers for drug delivery, Curr. Opin. Chem. Biol, 6, 466, 10.1016/S1367-5931(02)00347-2 Aulenta, 2003, Dendrimers: A new class of nanoscopic containers and delivery devices, Eur. Poly. J., 39, 1741, 10.1016/S0014-3057(03)00100-9 Cloninger, 2002, Biological applications of dendrimers, Curr. Opin. Chem. Biol, 6, 742, 10.1016/S1367-5931(02)00400-3 Ihre, 2002, Polyester dendritic systems for drug delivery applications: design, synthesis, and characterization, Bioconj. Chem, 13, 443, 10.1021/bc010102u PADILLA DE JESÚS, 2002, Polyester dendritic systems for drug delivery applications: in vitro and in vivo evaluation, Bioconj. Chem, 13, 453, 10.1021/bc010103m Kojima, 2000, Synthesis of polyamidoamine dendrimers having poly(ethylene glycol) grafts and their ability to encapsulate anticancer drugs, Bioconjug Chem, 11, 910, 10.1021/bc0000583 Kono, 1999, Design of dendritic macromolecules containing folate or methotrexate residues, Bioconjug Chem, 10, 1115, 10.1021/bc990082k Zhuo, 1999, In vitro release of 5-fluorouracil with cyclic core dendritic polymer, J. Control. Rel, 57, 249, 10.1016/S0168-3659(98)00120-5 Bhadra, 2003, A PEGylated dendritic nanoparticulate carrier of fluorouracil, Int. J. Pharm, 257, 111, 10.1016/S0378-5173(03)00132-7 Tripathi, 2002, Dendrimer grafts for delivery of 5-fluorouracil, Pharmazie, 57, 261 Ooya, 2003, Effects of ethylene glycol-based graft, star-shaped, and dendritic polymers on solubilization and controlled release of paclitaxel, J Control. Rel, 93, 121, 10.1016/j.jconrel.2003.07.001 Wang, 2000, Synthesis of starlike N-(2-hydroxypropyl)metha crylamide copolymers: potential drug carriers, Biomacromolecules, 1, 313, 10.1021/bm0000236 Fischer, 2003, In vitro cytotoxicity testing of polycations: influence of polymer structure on cell viability and hemolysis, Biomaterials, 24, 1121, 10.1016/S0142-9612(02)00445-3 Roberts, 1996, Preliminary biological evaluation of polyamidoamine (PAMAM) Starburst(tm) dendrimers, J. Biomed. Mat. Res, 30, 53, 10.1002/(SICI)1097-4636(199601)30:1<53::AID-JBM8>3.0.CO;2-Q Jevprasesphant, 2003, The influence of surface modification on the cytotoxicity of PAMAM dendrimers, Int. J. Pharm, 252, 263, 10.1016/S0378-5173(02)00623-3 Malik, 2000, Dendrimers: Relationship between structure and biocompatibility in vitro, and preliminary studies on the biodistribution of 125I-labelled polyamidoamine dendrimers in vivo, J. Control. Rel, 65, 133, 10.1016/S0168-3659(99)00246-1 Nigavekar, 2004, 3H dendrimer nanoparticle organ/tumor distribution, Pharm Res, 21, 476, 10.1023/B:PHAM.0000019302.26097.cc Wilbur, 1998, Biotin reagents for antibody pretargeting. 3. Synthesis, radioiodination and evaluation of biotinylated starbburst dendrimers, Bioconj. Chem, 9, 813, 10.1021/bc980055e Fuchs, 2004, A Surface-modified Dendrimer Set for Potential Application as Drug Delivery Vehicles: Synthesis, In vitro Toxicity, and Intracellular Localization, Chem. Eur. J, 10, 1167, 10.1002/chem.200305386 Grayson, 2000, Synthesis and Surface Functionalization of Aliphatic Polyether Dendrons, J. Am. Chem. Soc, 122, 10335, 10.1021/ja001903v Grayson, 2002, A New Approach to Heterofunctionalized Dendrimers: A Versatile Triallyl Chloride Core, Org. Lett, 4, 3171, 10.1021/ol0262993 Zhang, 2000, Dendrimers Based on Melamine. Divergent and Orthogonal, Convergent Syntheses of a G3 Dendrimer, Org. Lett, 2, 843, 10.1021/ol005585g Zhang, 2002, Structure-Activity Relationships in Dendrimers Based on Triazines: Gelation Depends on Choice of Linking and Surface Groups, Macromolecules, 35, 9015, 10.1021/ma021101f Steffensen, 2004, Synthesis and Manipulation of Orthogonally Protected Dendrimers: Building Blocks for Library Synthesis, Angew. Chem. Int. Ed., 43, 2, 10.1002/anie.200460031 Zhang, 2001, Synthesis and Characterization of Higher Generation Dendrons Based on p-Aminobenzylamine. Evidence for Molecular Recognition of Cu(II), Tetrahedron Lett., 42, 5355, 10.1016/S0040-4039(01)01007-3 Zhang, 2001, Orthogonal, Convergent Syntheses of Dendrimers Based on Melamine with One or Two Surface Sites for Manipulation, J. Am. Chem. Soc, 123, 8914, 10.1021/ja0041369 Zhang, 2003, Evaluation of Multivalent Dendrimers Based on Melamine: Kinetics of Thiol-Disulfide Exchange Depends on the Structure of the Dendrimer, J. Am. Chem. Soc., 125, 5086, 10.1021/ja0210906 Umali, 2003, Preparation of Multivalent Dendrimers Through Thiol-disulfide Exchange, Org. Lett., 5, 1245, 10.1021/ol034161u Bell, 2003, Synthesis and Characterization of DNA-Dendrimer Conjugates, Bioconj. Chem, 14, 488, 10.1021/bc020075n Steffensen, 2003, Chemoselective building blocks for dendrimers from relative reactivity data, Org. Lett., 5, 2359, 10.1021/ol0347491 Chen, 2004, Cytotoxicty, Hemolysis and Acute In vivo Toxicity of Dendrimers Based on Melamine, Candidate Vehicles for Drug Delivery, J. Am. Chem. Soc., 126, 10044, 10.1021/ja048548j Zhang, 2003, Triazine Dendrimers for Drug Delivery: Evaluation of Solubilization Properties, Activity in Cell Culture, and In vivo Toxicity of a Candidate Vehicle, Supramol. Chem., 15, 607, 10.1080/10610270310001605197 Neerman, 2004, In vitro and in vivo evaluation of a melamine dendrimer as a vehicle for drug delivery, Int. J. Pharm., 281, 129, 10.1016/j.ijpharm.2004.04.023 Jacobs, 1987, The role of lysine-132 and arginine-136 in the receptor-binding domain of the K99 fibrillar subunit, EMBO J., 6, 1805, 10.1002/j.1460-2075.1987.tb02434.x Neerman, 2004 Larsen, 2001, Synthesis and Biological Activity of Analogues of the Antidiabetic/Antiobesity Agent 3-Guanidinopropionic Acid: Discovery of a Novel Aminoguanidinoacetic Acid Antidiabetic Agent, J. Med. Chem, 44, 1217, 10.1021/jm000095f TRESTER-ZEDLITZ, 2003, A modular cross-linking approach for exploring protein interactions, J. Am. Chem. Soc, 125, 2416, 10.1021/ja026917a Adamczyk, 1998, Neopentyl 3-Triflyloxypropanesulfonate. A Reactive Sulfopropylation Reagent for the Preparation of Chemiluminescent Labels, J. Org. Chem., 63, 5636, 10.1021/jo980047r Rosowsky, 1988, Methotrexate analog. 32. Chain extension, alpha-carboxyl deletion, and gamma-carboxyl replacement by sulfonate and phosphate. Effect on enzyme binding and cell-growth inhibition, J. Med. Chem, 31, 1326, 10.1021/jm00402a012 Rosowsky, 2002, Synthesis of Quinolinylphosphane Oxides and -phosphonates from N-Arylimines Derived from Phosphane Oxides and Phosphonates, Eur. J. Org. Chem, 24, 4131 Maeda, 2000, Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review, J. Control. Rel, 65, 271, 10.1016/S0168-3659(99)00248-5 Maeda, 1992, Conjugates of anticancer agents and polymers: advantages of macromolecular therapeutic in vivo, Bioconj. Chem, 3, 351, 10.1021/bc00017a001 Ruoslahti, 2000, An address system in the vasculature of normal tissues and tumors, Annu. Rev. Immunol, 18, 813, 10.1146/annurev.immunol.18.1.813