Bifurcate evolution of quinone synthetases in basidiomycetes

citation_journal_title=Nat Prod Rep; citation_title=Pigments of fungi (macromycetes); citation_author=ZY Zhou, JK Liu; citation_volume=27; citation_issue=11; citation_publication_date=2010; citation_pages=1531-1570; citation_doi=10.1039/c004593d; citation_id=CR1 citation_journal_title=Fortschr Chem Org Naturst; citation_title=Pigments of fungi (Macromycetes); citation_author=M Gill, W Steglich; citation_volume=51; citation_publication_date=1987; citation_pages=1-317; citation_id=CR2 citation_journal_title=Proc Natl Acad Sci USA; citation_title=Bacterial endosymbionts protect beneficial soil fungus from nematode attack; citation_author=H Büttner, SP Niehs, K Vandelannoote, Z Cseresnyés, B Dose, I Richter, R Gerst, MT Figge, TP Stinear, SJ Pidot; citation_publication_date=2021; citation_doi=10.1073/pnas.2110669118; citation_id=CR3 citation_journal_title=Microb Biotechnol; citation_title=Interkingdom microbial consortia mechanisms to guide biotechnological applications; citation_author=S Zhang, N Merino, A Okamoto, P Gedalanga; citation_volume=11; citation_issue=5; citation_publication_date=2018; citation_pages=833-847; citation_doi=10.1111/1751-7915.13300; citation_id=CR4 citation_journal_title=Trends Biochem Sci; citation_title=Functional modulation of chemical mediators in microbial communities; citation_author=P Stallforth, M Mittag, AA Brakhage, C Hertweck, UA Hellmich; citation_volume=48; citation_issue=1; citation_publication_date=2023; citation_pages=71-81; citation_doi=10.1016/j.tibs.2022.07.006; citation_id=CR5 citation_journal_title=Annu Rev Genet; citation_title=Regulation and role of fungal secondary metabolites; citation_author=J Macheleidt, DJ Mattern, J Fischer, T Netzker, J Weber, V Schroeckh, V Valiante, AA Brakhage; citation_volume=50; citation_publication_date=2016; citation_pages=371-392; citation_doi=10.1146/annurev-genet-120215-035203; citation_id=CR6 citation_journal_title=Annu Rev Microbiol; citation_title=Chemical mediators at the bacterial-fungal interface; citation_author=K Scherlach, C Hertweck; citation_volume=74; citation_publication_date=2020; citation_pages=267-290; citation_doi=10.1146/annurev-micro-012420-081224; citation_id=CR7 citation_journal_title=Environ Microbiol; citation_title=Bacteria induce pigment formation in the basidiomycete Serpula lacrymans; citation_author=JP Tauber, V Schroeckh, E Shelest, AA Brakhage, D Hoffmeister; citation_volume=18; citation_issue=12; citation_publication_date=2016; citation_pages=5218-5227; citation_doi=10.1111/1462-2920.13558; citation_id=CR8 citation_journal_title=Environ Microbiol; citation_title=Bacterial cell wall-degrading enzymes induce basidiomycete natural product biosynthesis; citation_author=S Herkersdorf, T Krüger, P Wein, S Löffler, T Fontaine, M Gressler, C Hertweck, AA Brakhage, D Hoffmeister; citation_volume=23; citation_issue=8; citation_publication_date=2021; citation_pages=4360-4371; citation_doi=10.1111/1462-2920.15621; citation_id=CR9 citation_journal_title=Fungal Genet Biol; citation_title=Characterization of the atromentin biosynthesis genes and enzymes in the homobasidiomycete Tapinella panuoides; citation_author=P Schneider, S Bouhired, D Hoffmeister; citation_volume=45; citation_issue=11; citation_publication_date=2008; citation_pages=1487-1496; citation_doi=10.1016/j.fgb.2008.08.009; citation_id=CR10 citation_journal_title=ChemBioChem; citation_title=Characterization of the Suillus grevillei quinone synthetase GreA supports a nonribosomal code for aromatic α-keto acids; citation_author=B Wackler, G Lackner, YH Chooi, D Hoffmeister; citation_volume=13; citation_issue=12; citation_publication_date=2012; citation_pages=1798-1804; citation_doi=10.1002/cbic.201200187; citation_id=CR11 citation_journal_title=Chem Biol; citation_title=Three redundant synthetases secure redox-active pigment production in the basidiomycete Paxillus involutus; citation_author=J Braesel, S Götze, F Shah, D Heine, J Tauber, C Hertweck, A Tunlid, P Stallforth, D Hoffmeister; citation_volume=22; citation_issue=10; citation_publication_date=2015; citation_pages=1325-1334; citation_doi=10.1016/j.chembiol.2015.08.016; citation_id=CR12 citation_journal_title=Microbiol Spectr; citation_title=Blue light-dependent Pre-mRNA splicing controls pigment biosynthesis in the mushroom Terana caerulea; citation_author=S Lawrinowitz, JM Wurlitzer, D Weiss, HD Arndt, E Kothe, M Gressler, D Hoffmeister; citation_volume=10; citation_issue=5; citation_publication_date=2022; citation_pages=e0106522; citation_doi=10.1128/spectrum.01065-22; citation_id=CR13 citation_journal_title=Liebigs Ann Chem; citation_title=Über eine neue in der Natur vorkommende organische Säure; citation_author=C Stahlschmidt; citation_publication_date=1877; citation_doi=10.1002/jlac.18771870204; citation_id=CR14 citation_journal_title=Liebigs Ann Chem; citation_title=Untersuchungen über Pilzfarbstoffe. V. Die Konstitution der Polyporsäure; citation_author=F Kögl; citation_volume=447; citation_publication_date=1926; citation_pages=78-85; citation_doi=10.1002/jlac.19264470108; citation_id=CR15 citation_journal_title=EMBO J; citation_title=Structural basis for the activation of phenylalanine in the non-ribosomal biosynthesis of gramicidin S; citation_author=E Conti, T Stachelhaus, MA Marahiel, P Brick; citation_volume=16; citation_issue=14; citation_publication_date=1997; citation_pages=4174-4183; citation_doi=10.1093/emboj/16.14.4174; citation_id=CR16 citation_journal_title=J Biochem; citation_title=Molecular cloning and nucleotide sequence of the gramicidin S synthetase 1 gene; citation_author=K Hori, Y Yamamoto, T Minetoki, T Kurotsu, M Kanda, S Miura, K Okamura, J Furuyama, Y Saito; citation_volume=106; citation_issue=4; citation_publication_date=1989; citation_pages=639-645; citation_doi=10.1093/oxfordjournals.jbchem.a122909; citation_id=CR17 citation_journal_title=Fungal Biol Rev; citation_title=Fungal peptide synthetases: an update on functions and specificity signatures; citation_author=D Kalb, G Lackner, D Hoffmeister; citation_volume=27; citation_issue=2; citation_publication_date=2013; citation_pages=43-50; citation_doi=10.1016/j.fbr.2013.05.002; citation_id=CR18 citation_journal_title=Org Lett; citation_title=Design of α-Keto carboxylic acid dimers by domain recombination of nonribosomal peptide synthetase (NRPS)-like enzymes; citation_author=E Hühner, K Öquist, S-M Li; citation_volume=21; citation_issue=2; citation_publication_date=2019; citation_pages=498; citation_doi=10.1021/acs.orglett.8b03793; citation_id=CR19 citation_journal_title=Liebigs Ann Chem; citation_title=Fungal pigments 50 Synthesis of terphenylquinones via methoxide-catalyzed rearrangement of grevillin derivatives; citation_author=H-J Lohrisch, H Schmidt, W Steglich; citation_volume=1986; citation_publication_date=1986; citation_pages=195-204; citation_doi=10.1002/jlac.198619860117; citation_id=CR20 citation_journal_title=Molecules; citation_title=Secondary metabolites from the root rot biocontrol fungus Phlebiopsis gigantea; citation_author=D Kälvö, A Menkis, A Broberg; citation_volume=23; citation_issue=6; citation_publication_date=2018; citation_pages=1417; citation_doi=10.3390/molecules23061417; citation_id=CR21 citation_journal_title=ChemBioChem; citation_title=Genetic survey of Psilocybe natural products; citation_author=S Dörner, K Rogge, J Fricke, T Schäfer, JM Wurlitzer, M Gressler, DNK Pham, DR Manke, AR Chadeayne, D Hoffmeister; citation_publication_date=2022; citation_doi=10.1002/cbic.202200249; citation_id=CR22 citation_journal_title=Nat Protoc; citation_title=The Phyre2 web portal for protein modeling, prediction and analysis; citation_author=LA Kelley, S Mezulis, CM Yates, MN Wass, MJE Sternberg; citation_volume=10; citation_issue=6; citation_publication_date=2015; citation_pages=845-858; citation_doi=10.1038/nprot.2015.053; citation_id=CR23 citation_journal_title=J Biol Chem; citation_title=Catalytic mechanisms of Fe(II)- and 2-oxoglutarate-dependent oxygenases; citation_author=S Martinez, RP Hausinger; citation_volume=290; citation_issue=34; citation_publication_date=2015; citation_pages=20702-20711; citation_doi=10.1074/jbc.R115.648691; citation_id=CR24 citation_journal_title=Eur J Biochem; citation_title=The 2-His-1-carboxylate facial triad-an emerging structural motif in mononuclear non-heme iron(II) enzymes; citation_author=EL Hegg, L Que; citation_volume=250; citation_issue=3; citation_publication_date=1997; citation_pages=625-629; citation_doi=10.1111/j.1432-1033.1997.t01-1-00625.x; citation_id=CR25 citation_journal_title=Nucleic Acids Res; citation_title=Molecular basis for the substrate specificity and catalytic mechanism of thymine-7-hydroxylase in fungi; citation_author=W Li, T Zhang, J Ding; citation_volume=43; citation_issue=20; citation_publication_date=2015; citation_pages=10026-10038; citation_id=CR26 citation_journal_title=ChemRxiv; citation_title=Radical tropolone biosynthesis; citation_author=TJ Doyon, K Skinner, D Yang, L Mallik, T Wymore, M Koutmos, PM Zimmerman, A Narayan; citation_publication_date=2020; citation_doi=10.26434/chemrxiv.12780044.v1; citation_id=CR27 citation_journal_title=ACS Chem Biol; citation_title=Monoamine biosynthesis via a noncanonical calcium-activatable aromatic amino acid decarboxylase in psilocybin mushroom; citation_author=MP Torrens-Spence, CT Liu, T Pluskal, YK Chung, JK Weng; citation_volume=13; citation_issue=12; citation_publication_date=2018; citation_pages=3343-3353; citation_doi=10.1021/acschembio.8b00821; citation_id=CR28 citation_journal_title=Front Microbiol; citation_title=A new high-performance heterologous fungal expression system based on regulatory elements from the Aspergillus terreus terrein gene cluster; citation_author=M Gressler, P Hortschansky, E Geib, M Brock; citation_volume=6; citation_publication_date=2015; citation_pages=184; citation_doi=10.3389/fmicb.2015.00184; citation_id=CR29 citation_journal_title=Fungal Biol Biotechnol; citation_title=ATNT: an enhanced system for expression of polycistronic secondary metabolite gene clusters in Aspergillus niger; citation_author=E Geib, M Brock; citation_volume=4; citation_publication_date=2017; citation_pages=13; citation_doi=10.1186/s40694-017-0042-1; citation_id=CR30 citation_journal_title=Cell Chem Biol.; citation_title=Cross-chemistry leads to product diversity from atromentin synthetases in Aspergilli from section Nigri; citation_author=E Geib, F Baldeweg, M Doerfer, M Nett, M Brock; citation_volume=26; citation_issue=2; citation_publication_date=2019; citation_pages=223-234; citation_doi=10.1016/j.chembiol.2018.10.021; citation_id=CR31 citation_journal_title=Cell Chem Biol; citation_title=A non-canonical melanin biosynthesis pathway protects Aspergillus terreus conidia from environmental stress; citation_author=E Geib, M Gressler, I Viediernikova, F Hillmann, ID Jacobsen, S Nietzsche, C Hertweck, M Brock; citation_volume=23; citation_issue=5; citation_publication_date=2016; citation_pages=587-597; citation_doi=10.1016/j.chembiol.2016.03.014; citation_id=CR32 citation_journal_title=Angew Chem Int Ed; citation_title=Unprecedented mushroom polyketide synthases produce the universal anthraquinone precursor; citation_author=NA Löhr, F Eisen, W Thiele, L Platz, J Motter, W Hüttel, M Gressler, M Müller, D Hoffmeister; citation_volume=61; citation_issue=24; citation_publication_date=2022; citation_pages=e202116142; citation_doi=10.1002/anie.202116142; citation_id=CR33 citation_journal_title=PLoS Genet; citation_title=Analysis of the Phlebiopsis gigantea genome, transcriptome and secretome provides insight into its pioneer colonization strategies of wood; citation_author=C Hori, T Ishida, K Igarashi, M Samejima, H Suzuki, E Master, P Ferreira, FJ Ruiz-Dueñas, B Held, P Canessa; citation_volume=10; citation_issue=12; citation_publication_date=2014; citation_pages=e1004759; citation_doi=10.1371/journal.pgen.1004759; citation_id=CR34 citation_journal_title=Angew Chem Int Ed; citation_title=Nonribosomal peptide synthesis—principles and prospects; citation_author=RD Süssmuth, A Mainz; citation_volume=56; citation_issue=14; citation_publication_date=2017; citation_pages=3770-3821; citation_doi=10.1002/anie.201609079; citation_id=CR35 citation_journal_title=Ber Dtsch Chem Ges; citation_title=Über einen in einer Agaricus-Art vorkommenden chinonartigen Körper; citation_author=W Thörner; citation_volume=11; citation_issue=1; citation_publication_date=1878; citation_pages=533-535; citation_doi=10.1002/cber.187801101143; citation_id=CR36 citation_journal_title=Chem Rev; citation_title=Natural terphenyls: developments since 1877; citation_author=JK Liu; citation_volume=106; citation_issue=6; citation_publication_date=2006; citation_pages=2209-2223; citation_doi=10.1021/cr050248c; citation_id=CR37 citation_journal_title=Zeitschrift für Mykologie; citation_title=Wirkung von Pilzfruchtkörpern auf Drosophila-Maden; citation_author=H Besl, C Krump, M Schefcsik; citation_volume=53; citation_publication_date=1987; citation_pages=273-282; citation_id=CR38 citation_journal_title=Microbiology (Reading); citation_title=Dissimilar pigment regulation in Serpula lacrymans and Paxillus involutus during inter-kingdom interactions; citation_author=JP Tauber, R Gallegos-Monterrosa, AT Kovacs, E Shelest, D Hoffmeister; citation_volume=164; citation_issue=1; citation_publication_date=2018; citation_pages=65-77; citation_doi=10.1099/mic.0.000582; citation_id=CR39 citation_journal_title=Science; citation_title=The plant cell wall-decomposing machinery underlies the functional diversity of forest fungi; citation_author=DC Eastwood, D Floudas, M Binder, A Majcherczyk, P Schneider, A Aerts, FO Asiegbu, SE Baker, K Barry, M Bendiksby; citation_volume=333; citation_issue=6043; citation_publication_date=2011; citation_pages=762-765; citation_doi=10.1126/science.1205411; citation_id=CR40 citation_journal_title=Microorganisms; citation_title=Secretion of iron (III)-reducing metabolites during protein acquisition by the ectomycorrhizal fungus Paxillus involutus; citation_author=F Shah, M Gressler, S Nehzati, M Op De Beeck, L Gentile, D Hoffmeister, P Persson, A Tunlid; citation_volume=9; citation_issue=1; citation_publication_date=2020; citation_pages=35; citation_doi=10.3390/microorganisms9010035; citation_id=CR41 citation_journal_title=ChemBioChem; citation_title=Activity of α-aminoadipate reductase depends on the N-terminally extending domain; citation_author=D Kalb, G Lackner, M Rappe, D Hoffmeister; citation_volume=16; citation_issue=10; citation_publication_date=2015; citation_pages=1426-1430; citation_doi=10.1002/cbic.201500190; citation_id=CR42 citation_journal_title=Experientia; citation_title=Psilocybin, a psychotropic substance from the Mexican mushroom Psilocybe mexicana Heim; citation_author=A Hofmann, R Heim, A Brack, H Kobel; citation_volume=14; citation_issue=3; citation_publication_date=1958; citation_pages=107-109; citation_doi=10.1007/BF02159243; citation_id=CR43 citation_journal_title=J Pharm Sci; citation_title=Baeocystin and norbaeocystin: new analogs of psilocybin from Psilocybe baeocystis; citation_author=AY Leung, AG Paul; citation_volume=57; citation_issue=10; citation_publication_date=1968; citation_pages=1667-1671; citation_doi=10.1002/jps.2600571007; citation_id=CR44 citation_journal_title=ChemBioChem; citation_title=Iterative L-tryptophan methylation in Psilocybe evolved by subdomain duplication; citation_author=F Blei, J Fricke, J Wick, JC Slot, D Hoffmeister; citation_volume=19; citation_issue=20; citation_publication_date=2018; citation_pages=2160-2166; citation_doi=10.1002/cbic.201800336; citation_id=CR45 citation_journal_title=Chemistry; citation_title=Simultaneous production of psilocybin and a cocktail of β-carboline monoamine oxidase inhibitors in "magic" mushrooms; citation_author=F Blei, S Dörner, J Fricke, F Baldeweg, F Trottmann, A Komor, F Meyer, C Hertweck, D Hoffmeister; citation_volume=26; citation_issue=3; citation_publication_date=2020; citation_pages=729-734; citation_doi=10.1002/chem.201904363; citation_id=CR46 citation_journal_title=J Nat Prod; citation_title=Identification of ω-N-Methyl-4-hydroxytryptamine (Norpsilocin) as a Psilocybe Natural Product; citation_author=C Lenz, J Wick, D Hoffmeister; citation_volume=80; citation_issue=10; citation_publication_date=2017; citation_pages=2835-2838; citation_doi=10.1021/acs.jnatprod.7b00407; citation_id=CR47 citation_journal_title=Front Microbiol; citation_title=Microbial communication leading to the activation of silent fungal secondary metabolite gene clusters; citation_author=T Netzker, J Fischer, J Weber, DJ Mattern, CC König, V Valiante, V Schroeckh, AA Brakhage; citation_volume=6; citation_publication_date=2015; citation_pages=299; citation_doi=10.3389/fmicb.2015.00299; citation_id=CR48 citation_journal_title=Proc Natl Acad Sci U S A; citation_title=Intimate bacterial-fungal interaction triggers biosynthesis of archetypal polyketides in Aspergillus nidulans; citation_author=V Schroeckh, K Scherlach, HW Nützmann, E Shelest, W Schmidt-Heck, J Schuemann, K Martin, C Hertweck, AA Brakhage; citation_volume=106; citation_issue=34; citation_publication_date=2009; citation_pages=14558-14563; citation_doi=10.1073/pnas.0901870106; citation_id=CR49 citation_journal_title=Mol Microbiol; citation_title=Bacteria-induced production of the antibacterial sesquiterpene lagopodin B in Coprinopsis cinerea; citation_author=M Stöckli, BI Morinaka, G Lackner, A Kombrink, R Sieber, C Margot, CE Stanley, AJ deMello, J Piel, M Künzler; citation_volume=112; citation_issue=2; citation_publication_date=2019; citation_pages=605-619; citation_doi=10.1111/mmi.14277; citation_id=CR50 citation_journal_title=Adv Genet; citation_title=The genetics of Aspergillus nidulans; citation_author=G Pontecorvo, JA Roper, LM Hemmons, KD Macdonald, AW Bufton; citation_volume=5; citation_publication_date=1953; citation_pages=141-238; citation_doi=10.1016/S0065-2660(08)60408-3; citation_id=CR51 citation_journal_title=G3 (Bethesda); citation_title=Chromosome assembled and annotated genome sequence of Aspergillus flavus NRRL 3357; citation_author=JM Skerker, KM Pianalto, SJ Mondo, K Yang, AP Arkin, NP Keller, IV Grigoriev, NL Louise Glass; citation_publication_date=2021; citation_doi=10.1093/g3journal/jkab213; citation_id=CR52 citation_journal_title=Plant Methods; citation_title=Protocol: a simple method for extracting next-generation sequencing quality genomic DNA from recalcitrant plant species; citation_author=A Healey, A Furtado, T Cooper, RJ Henry; citation_volume=10; citation_publication_date=2014; citation_pages=21; citation_doi=10.1186/1746-4811-10-21; citation_id=CR53 citation_journal_title=J Antibiot (Tokyo); citation_title=The Laetiporus polyketide synthase LpaA produces a series of antifungal polyenes; citation_author=PS Seibold, C Lenz, M Gressler, D Hoffmeister; citation_volume=73; citation_issue=10; citation_publication_date=2020; citation_pages=711-720; citation_doi=10.1038/s41429-020-00362-6; citation_id=CR54 citation_journal_title=ChemBioChem; citation_title=S-Adenosyl-L-methionine salvage impacts psilocybin formation in "magic" mushrooms; citation_author=R Demmler, J Fricke, S Dörner, M Gressler, D Hoffmeister; citation_volume=21; citation_issue=9; citation_publication_date=2020; citation_pages=1364-1371; citation_doi=10.1002/cbic.201900649; citation_id=CR55 citation_journal_title=J Fungi (Basel); citation_title=Regulation of the leucine metabolism in Mortierella alpina; citation_author=R Sonnabend, L Seiler, M Gressler; citation_volume=8; citation_issue=2; citation_publication_date=2022; citation_pages=196; citation_doi=10.3390/jof8020196; citation_id=CR56 citation_journal_title=Nucleic Acids Res; citation_title=A new mathematical model for relative quantification in real-time RT-PCR; citation_author=MW Pfaffl; citation_volume=29; citation_issue=9; citation_publication_date=2001; citation_pages=e45; citation_doi=10.1093/nar/29.9.e45; citation_id=CR57 citation_journal_title=Nat Biotechnol; citation_title=De novo assembly of haplotype-resolved genomes with trio binning; citation_author=S Koren, A Rhie, BP Walenz, AT Dilthey, DM Bickhart, SB Kingan, S Hiendleder, JL Williams, TPL Smith, AM Phillippy; citation_volume=36; citation_publication_date=2018; citation_pages=1174-1182; citation_doi=10.1038/nbt.4277; citation_id=CR58 citation_journal_title=Genome Res; citation_title=Canu: scalable and accurate long-read assembly via adaptive k-mer weighting and repeat separation; citation_author=S Koren, BP Walenz, K Berlin, JR Miller, NH Bergman, AM Phillippy; citation_volume=27; citation_issue=5; citation_publication_date=2017; citation_pages=722-736; citation_doi=10.1101/gr.215087.116; citation_id=CR59 citation_journal_title=Nat Methods; citation_title=A complete bacterial genome assembled de novo using only nanopore sequencing data; citation_author=NJ Loman, J Quick, JT Simpson; citation_volume=12; citation_issue=8; citation_publication_date=2015; citation_pages=733-735; citation_doi=10.1038/nmeth.3444; citation_id=CR60 citation_journal_title=Genome Biol; citation_title=Performance of neural network basecalling tools for Oxford Nanopore sequencing; citation_author=RR Wick, LM Judd, KE Holt; citation_volume=20; citation_issue=1; citation_publication_date=2019; citation_pages=129; citation_doi=10.1186/s13059-019-1727-y; citation_id=CR61 citation_journal_title=Bioinformatics; citation_title=Minimap2: pairwise alignment for nucleotide sequences; citation_author=H Li; citation_volume=34; citation_issue=18; citation_publication_date=2018; citation_pages=3094-3100; citation_doi=10.1093/bioinformatics/bty191; citation_id=CR62 citation_journal_title=Bioinformatics; citation_title=The sequence alignment/map format and SAMtools; citation_author=H Li, B Handsaker, A Wysoker, T Fennell, J Ruan, N Homer, G Marth, G Abecasis, R Durbin; citation_volume=25; citation_issue=16; citation_publication_date=2009; citation_pages=2078-2079; citation_doi=10.1093/bioinformatics/btp352; citation_id=CR63 citation_journal_title=Gigascience; citation_title=Twelve years of SAMtools and BCFtools; citation_author=P Danecek, JK Bonfield, J Liddle, J Marshall, V Ohan, MO Pollard, A Whitwham, T Keane, SA McCarthy, RM Davies; citation_publication_date=2021; citation_doi=10.1093/gigascience/giab008; citation_id=CR64 citation_journal_title=Genomics Proteomics Bioinformatics; citation_title=Oxford nanopore MinION sequencing and genome assembly; citation_author=H Lu, F Giordano, Z Ning; citation_volume=14; citation_issue=5; citation_publication_date=2016; citation_pages=265-279; citation_doi=10.1016/j.gpb.2016.05.004; citation_id=CR65 citation_journal_title=Nucleic Acids Res; citation_title=AUGUSTUS: a web server for gene finding in eukaryotes; citation_author=M Stanke, R Steinkamp, S Waack, B Morgenstern; citation_volume=32; citation_publication_date=2004; citation_pages=W309-312; citation_doi=10.1093/nar/gkh379; citation_id=CR66 citation_journal_title=Nucleic Acids Res; citation_title=Gapped BLAST and PSI-BLAST: a new generation of protein database search programs; citation_author=SF Altschul, TL Madden, AA Schaffer, J Zhang, Z Zhang, W Miller, DJ Lipman; citation_volume=25; citation_issue=17; citation_publication_date=1997; citation_pages=3389-3402; citation_doi=10.1093/nar/25.17.3389; citation_id=CR67 citation_journal_title=Mol Biol Evol; citation_title=MEGA X: molecular evolutionary genetics analysis across computing platforms; citation_author=S Kumar, G Stecher, M Li, C Knyaz, K Tamura; citation_volume=35; citation_issue=6; citation_publication_date=2018; citation_pages=1547-1549; citation_doi=10.1093/molbev/msy096; citation_id=CR68 citation_journal_title=Bioinformatics; citation_title=Clustal W and Clustal X version 2.0; citation_author=MA Larkin, G Blackshields, NP Brown, R Chenna, PA McGettigan, H McWilliam, F Valentin, IM Wallace, A Wilm, R Lopez; citation_volume=23; citation_issue=21; citation_publication_date=2007; citation_pages=2947-2948; citation_doi=10.1093/bioinformatics/btm404; citation_id=CR69 citation_journal_title=Mol Biol Evol; citation_title=An improved general amino acid replacement matrix; citation_author=SQ Le, O Gascuel; citation_volume=25; citation_issue=7; citation_publication_date=2008; citation_pages=1307-1320; citation_doi=10.1093/molbev/msn067; citation_id=CR70 citation_journal_title=Comput Appl Biosci; citation_title=The rapid generation of mutation data matrices from protein sequences; citation_author=DT Jones, WR Taylor, JM Thornton; citation_volume=8; citation_issue=3; citation_publication_date=1992; citation_pages=275-282; citation_id=CR71 citation_journal_title=Evolution; citation_title=Confidence limits on phylogenies: an approach using the bootstrap; citation_author=J Felsenstein; citation_volume=39; citation_issue=4; citation_publication_date=1985; citation_pages=783-791; citation_doi=10.2307/2408678; citation_id=CR72 citation_journal_title=Nat Methods; citation_title=ColabFold: making protein folding accessible to all; citation_author=M Mirdita, K Schütze, Y Moriwaki, L Heo, S Ovchinnikov, M Steinegger; citation_volume=19; citation_issue=6; citation_publication_date=2022; citation_pages=679-682; citation_doi=10.1038/s41592-022-01488-1; citation_id=CR73 citation_journal_title=Protein Sci; citation_title=UCSF ChimeraX: meeting modern challenges in visualization and analysis; citation_author=TD Goddard, CC Huang, EC Meng, EF Pettersen, GS Couch, JH Morris, TE Ferrin; citation_volume=27; citation_issue=1; citation_publication_date=2018; citation_pages=14-25; citation_doi=10.1002/pro.3235; citation_id=CR74 citation_journal_title=Protein Sci; citation_title=UCSF ChimeraX: structure visualization for researchers, educators, and developers; citation_author=EF Pettersen, TD Goddard, CC Huang, EC Meng, GS Couch, TI Croll, JH Morris, TE Ferrin; citation_volume=30; citation_issue=1; citation_publication_date=2021; citation_pages=70-82; citation_doi=10.1002/pro.3943; citation_id=CR75 citation_journal_title=Acta Crystallogr D Biol Crystallogr; citation_title=Structure of the adenylation-peptidyl carrier protein didomain of the Microcystis aeruginosa microcystin synthetase McyG; citation_author=XF Tan, YN Dai, K Zhou, YL Jiang, YM Ren, Y Chen, CZ Zhou; citation_volume=71; citation_issue=Pt 4; citation_publication_date=2015; citation_pages=873-881; citation_doi=10.1107/S1399004715001716; citation_id=CR76 citation_journal_title=Eur J Org Chem; citation_title=Synthesis of a focused chemical library based on derivatives of embelin, a natural product with proapoptotic and anticancer properties; citation_author=G Viault, D Gree, S Das, JS Yadav, R Gree; citation_volume=2011; citation_issue=7; citation_publication_date=2011; citation_pages=1233-1241; citation_doi=10.1002/ejoc.201001627; citation_id=CR77 citation_journal_title=Chem Commun (Camb); citation_title=Fluorous-tagged indolylboron for the diversity-oriented synthesis of biologically-attractive bisindole derivatives; citation_author=T Kasahara, Y Kondo; citation_volume=8; citation_publication_date=2006; citation_pages=891-893; citation_doi=10.1039/b516487g; citation_id=CR78