Bevacizumab plus chemotherapy versus chemotherapy alone as second-line treatment for patients with HER2-negative locally recurrent or metastatic breast cancer after first-line treatment with bevacizumab plus chemotherapy (TANIA): an open-label, randomised phase 3 trial

The Lancet Oncology - Tập 15 Số 11 - Trang 1269-1278 - 2014
Gϋnter von Minckwitz1, Fabio Puglisi2, Javier Cortés3, Eduard Vrdoljak4, Norbert Marschner5, Christoph Zielinski6, Cristian Villanueva7, Gilles Romieu8, István Láng9, Eva Ciruelos10, Michelino De Laurentiis11, Corinne Veyret12, Sabine de Ducla13, Ulrich Freudensprung13, Stefanie Srock13, Joseph Gligorov14
1German Breast Group, Neu-Isenburg, and University Women's Hospital, Frankfurt, Germany
2University Hospital of Udine, Udine, Italy
3Vall d'Hebron Institute of Oncology and Vall d'Hebron University Hospital, Barcelona, Spain.
4Center of Oncology, University Hospital Split, Split, Croatia
5Outpatient Cancer Center, Freiburg, Germany
6Department of Medicine I and Comprehensive Cancer Center, Medical University Vienna, Vienna, Austria
7Centre Hospitalier-Universitaire de Besançon, Besançon, France
8Institut du Cancer Montpellier, Val d'Aurelle, France
9National Institute of Oncology, Budapest, Hungary
10Hospital Universitario 12 Octubre, Madrid, Spain
11Istituto Nazionale Tumori, Fondazione 'G. Pascale', Naples, Italy
12Centre Henri Becquerel, Rouen, France
13F. Hoffmann-La Roche Ltd, Basel, Switzerland
14Assistance-Publique Hôpitaux de Paris-Tenon, Institut Universitaire de Cancerologie Université Pierre et Marie Curie, Sorbonne Université, Paris, France

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