Liệu pháp beta-blocker có liên quan đến việc cải thiện chức năng tâm thu thất trái và khả năng luyện tập bền bỉ ở bệnh nhân cao tuổi mắc suy tim. Nghiên cứu phụ CIBIS-ELD

Jessup M, Brozena S. Heart failure. N Engl J Med 2003; 348: 2007–18. Mancini DM, Eisen H, Kussmaul W et al. Value of peak oxygen consumption for optimal timing of cardiac transplantation in ambulatory patients with heart failure. Circulation 1991: 83: 778–86. Myers J, Arena R, Dewey F et al. A cardiopulmonary exercise testing score for predicting outcome in patients with heart failure. Am Heart J 2008; 156: 1177–83. Wagoner LE, Craft LL, Singh B et al. Polymorphisms of the beta( 2)-adrenergic receptor determine exercise capacity in patients with heart failure. Circ Res 2000; 86: 834–40. Task Force of the Italian Working Group on Cardiac Rehabilitation Prevention; Working Group on Cardiac Rehabilitation and Exercise Physiology of the European Society of Cardiology, Piepoli MF, Corrà U, Agostoni PG et al. Statement on cardiopulmonary exercise testing in chronic heart failure due to left ventricular dysfunction: recommendations for performance and interpretation. Part I: Definition of cardiopulmonary exercise testing parameters for appropriate use in chronic heart failure. Eur J Cardiovasc Prev Rehabil 2006; 13: 150–64. Guazzi M, Agostoni P, Matturri M et al. Pulmonary function, cardiac function, and exercise capacity in a follow-up of patients with congestive heart failure treated with carvedilol. Am Heart J 1999; 138: 460–7. Australia/New Zealand Heart Failure Research Collaborative Group. Randomised, placebo-controlled trial of carvedilol in patients with congestive heart failure due to ischaemic heart disease. Lancet 1997; 349: 375–80. Düngen HD, Apostolovic S, Inkrot S et al. Bisoprolol vs. carvedilol in elderly patients with heart failure: rationale and design of the CIBIS-ELD trial. Clin Res Cardiol 2008; 97: 578–86. Lang RM, Bierig M, Devereux RB et al. American Society of Echocardiography’s Guidelines and Standards Committee; European Association of Echocardiography. Recommendations for chamber quantification: a report from the American Society of Echocardiography’s Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. J Am Soc Echocardiogr 2005; 18: 1440–63. Buchner S, Muscholl M, Debl K et al. Left atrial size by planimetry is superior to M-mode diameter: biochemical calibration by atrial and brain natriuretic peptide. J Am Soc Echocardiogr 2008; 21: 380–5. Ommen SR, Nishimura RA, Appleton CP et al. Clinical utility of Doppler echocardiography and tissue Doppler imaging in estimation of left ventricular filling pressure: a comparative simultaneous Doppler-catheterization study. Circulation 2000; 102: 788–94. Clark AL, Cleland JG. How do you measure exercise capacity in chronic heart failure? Eur Heart J 2001; 22: 627–8. Borg G. Subjective effort and physical activities. Scand J Rehabil 1978; 6: 108–13. Witte KA, Thackray S, Nikitin NP et al. The effects of long term beta blockade on the ventilatory responses to exercise in chronic heart failure. Eur J Heart Fail 2005; 7: 612–7. Metra M, Giubbini R, Nodari S et al. Differential effects of beta blockers in patients with heart failure. Circulation 2000; 102: 546–51. Jost A, Rauch B, Hochadel M et al. Beta-blocker treatment of chronic systolic heart failure improves prognosis even in patients meeting one or more exclusion criteria of the MERIT-HF study. Eur Heart J 2005; 26: 2689–97. Corra U, Mezzani A, Giordano A et al. Exercise haemodynamic variables rather than ventilatory efficiency indexes contribute to risk assessment in chronic heart failure patients treated with carvedilol. Eur Heart J 2009; 30: 3000–6. Cohen-Solal A, Beauvais F, Tan LB. Peak exercise responses in heart failure: back to basics. Eur Heart J 2009; 30: 2962–4. Zukck C, Haustetter A, Kruger C et al. Impact of beta-blocker treatment on the prognostic value of currently used risk predictors in congestive heart failure. J Am Coll Cardiol 2002; 38: 1615–22. Mezzani A, Corrà U, Bosimini E et al. Contribution of peak res- piratory exchange ratio to peak VO2 prognostic reliability in patients with chronic heart failure and severely reduced exercise capacity. Am Heart J 2003; 145: 1102–7. Albouaini K, Egred M, Alahmar A et al. Cardiopulmonary exercise testing and its application. Heart 2007; 93: 1285–92. Lars HL, Mancini DM. Peak VO2 in elderly patients with heart failure. Int J Cardiol 2007; 125: 166–71. Davies LC, Wensel R, Georgladou P et al. Enhanced prognostic value from cardiopulmonary exercise testing in chronic failure by non-linear analysis: oxygen uptake efficiency slope. Eur Heart J 2006; 27: 684–90. Ingle L, Witte KK, Cleland JF et al. The prognostic value of cardiopulmonary exercise testing with a peak respiratory exchange ratio of <1.0 in patients with chronic heart failure. Int J Cardiol 2008; 127: 88–92. Oliveira RB, Myers J, Araújo CG et al. Does peak oxygen pulse complement peak oxygen uptake in risk stratifying patients with heart failure? Am J Cardiol 2009; 104: 554–8. Giardini A, Lovato L, Donti A et al. A pilot study on the effects of carvedilol on right ventricular remodeling and excersise tolerance in patients with systemic right ventricle. Int J Cardiol 2007; 114: 241–6. King GJ, Murphy RT, Almuntaser I et al. Alterations in myocardial stiffness in elite athletes assessed by a new Doppler index Heart 2008; 94: 1323–5. Gardin JM, Leifer ES, Fleg JL et al. Relationship of dopplerechocardiographic left ventricular diastolic function to exercise performance in systolic heart failure: The HF-ACTION study. Am Heart J 2009; 158: S45–52. Donal E, Raud-Raynier P, De Place C et al. Resting echocardiographic assessment of left atrial function and filling pressure interest in the understanding of exercise capacity in patients with chronic congestive heart failure. J Am Soc Echocardiogr 2008; 21: 703–10. Smart N, Haluska B, Leano R et al. Determinants of functional capacity in patients with chronic heart failure: role of filling pressure and systolic and diastolic function. Am Heart J 2005; 149: 152–8. Dungen HD, Apostolovic S, Incrote S et al. Titration to target dose of bisoprolol vs carvedilol in elderly patients with heart failure: the CIBIS-ELD trial. Eur J Heart Fail 2011; 13: 670–80. Gelbrich G, Edelmann F, Incrot S et al. Is target dose the treatment target? Uptitrating beta-blockers for heart failure in the elderly. Int J Cardiol 2012; 155: 160–6. Effect of age on treatment, trends and outcome of patients hospitalized with atrial fibrillation: insights from a 20-years registry in a middle-eastern country (1991-2010)