Basic Science of Articular Cartilage and Osteoarthritis

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Mow, 1989, Biomechanics of articular cartilage, 31

Wong, 1996, Zone-specific cell biosynthetic activity in mature bovine articular cartilage: a new method using confocal microscopic stereology and quantitative autoradiography, J Orthop Res, 14, 424, 10.1002/jor.1100140313

Schumacher, 1999, Immunodetection and partial cDNA sequence of the proteoglycan, superficial zone protein, synthesized by cells lining synovial joints, J Orthop Res, 17, 110, 10.1002/jor.1100170117

Schumacher, 1994, A novel proteoglycan synthesized and secreted by chondrocytes of the superficial zone of articular cartilage, Arch Biochem Biophys, 311, 144, 10.1006/abbi.1994.1219

Klein, 2003, Tissue engineering of stratified articular cartilage from chondrocyte subpopulations, Osteoarthritis Cartilage, 11, 595, 10.1016/S1063-4584(03)00090-6

Macirowski, 1994, Cartilage stresses in the human hip joint, J Biomech Eng, 116, 10, 10.1115/1.2895693

Ateshian, 1997, Rolling resistance of articular cartilage due to interstitial fluid flow, Proc Inst Mech Eng [H], 211, 419, 10.1243/0954411971534548

Soltz, 2000, Interstitial fluid pressurization during confined compression cyclical loading of articular cartilage, Ann Biomed Eng, 28, 150, 10.1114/1.239

Soltz, 1998, Experimental verification and theoretical prediction of cartilage interstitial fluid pressurization at an impermeable contact interface in confined compression, J Biomech, 31, 927, 10.1016/S0021-9290(98)00105-5

Mankin, 1999, Articular cartilage structure, composition, and function, 444

Maroudas, 1976, Balance between swelling pressure and collagen tension in normal and degenerate cartilage, Nature, 260, 808, 10.1038/260808a0

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Mankin, 1982, The response of articular cartilage to mechanical injury, J Bone Joint Surg Am, 64, 460, 10.2106/00004623-198264030-00022

Mankin, 1999, Articular cartilage repair and osteoarthritis, 472

Akizuki, 1987, Tensile properties of human knee joint cartilage. II. Correlations between weight bearing and tissue pathology and the kinetics of swelling, J Orthop Res, 5, 173, 10.1002/jor.1100050204

Lai, 1991, A triphasic theory for the swelling and deformation behaviors of articular cartilage, J Biomech Eng, 113, 245, 10.1115/1.2894880

Setton, 1994, Mechanical properties of canine articular cartilage are significantly altered following transection of the anterior cruciate ligament, J Orthop Res, 12, 451, 10.1002/jor.1100120402

Lyyra, 1999, In vivo characterization of indentation stiffness of articular cartilage in the normal human knee, J Biomed Mater Res, 48, 482, 10.1002/(SICI)1097-4636(1999)48:4<482::AID-JBM13>3.0.CO;2-M

Franz, 2001, In situ compressive stiffness, biochemical composition, and structural integrity of articular cartilage of the human knee joint, Osteoarthritis Cartilage, 9, 582, 10.1053/joca.2001.0418

Bae, 2003, Indentation testing of human cartilage: sensitivity to articular surface degeneration, Arthritis Rheum, 48, 3382, 10.1002/art.11347

Wang H., Strauch R.J., Ateshian G.A., Pawluck R.J., Xu L., Rosenwasser M.P. Variations of compressive stiffness and thickness of the thumb carpometacarpal joint cartilage with degeneration and age. Orthopaedic Research Society 44th Annual Meeting, New Orleans (LA); March 16–19, 1998

Chevalier, 1997, Is a biological marker for osteoarthritis within reach, Rev Rheum, 64, 562

Wollheim, 1999, Serum markers of articular cartilage damage and repair, Rheum Dis Clin North Am, 25, 417, 10.1016/S0889-857X(05)70076-4

Lindhorst, 2000, Longitudinal characterization of synovial fluid biomarkers in the canine meniscectomy model of osteoarthritis, J Ortho Res, 18, 269, 10.1002/jor.1100180216

Bashir, 1999, Nondestructive imaging of human cartilage glycosaminoglycan concentration by MRI, Magn Reson Med, 41, 857, 10.1002/(SICI)1522-2594(199905)41:5<857::AID-MRM1>3.0.CO;2-E

Tiderius, 2003, Delayed gadolinium-enhanced MRI of cartilage (dGEMRIC) in early knee osteoarthritis, Magn Reson Med, 49, 488, 10.1002/mrm.10389

Wang, 2003, Cell orientation determines the alignment of cell-produced collagenous matrix, J Biomech, 36, 97, 10.1016/S0021-9290(02)00233-6

Nieminen, 2001, T2 relaxation reveals spatial collagen architecture in articular cartilage: a comparative quantitative MRI and polarized light microscopic study, Magn Reson Med, 46, 487, 10.1002/mrm.1218

Xia, 2001, Quantitative in situ correlation between microscopic MRI and polarized light microscopy studies of articular cartilage, Osteoarthritis Cartilage, 9, 393, 10.1053/joca.2000.0405

Maier, 2003, T2 quantitation of articular cartilage at 1.5 T, J Magn Reson Imaging, 17, 358, 10.1002/jmri.10263

Reboul, 1996, The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis, J Clin Invest, 97, 2011, 10.1172/JCI118636

Martel-Pelletier, 2004, Pathophysiology of osteoarthritis, Osteoarthritis Cartilage, 12, S31, 10.1016/j.joca.2003.10.002

Lark, 1997, Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints, J Clin Invest, 100, 93, 10.1172/JCI119526

Tortorella, 2000, Sites of aggrecan cleavage by recombinant human aggrecanase-1 (ADAMTS-4), J Biol Chem, 275, 18566, 10.1074/jbc.M909383199

Choy, 2002, Therapeutic benefit of blocking interleukin-6 activity with an anti-interleukin-6 receptor monoclonal antibody in rheumatoid arthritis: a randomized, double-blind, placebo-controlled, dose-escalation trial, Arthritis Rheum, 46, 3143, 10.1002/art.10623

Brandt K.D., Mazzuca S.A., Katz B.P., Lane K.A. Doxycycline (Doxy) slows the rate of joint space narrowing (JSN) in patients with knee osteoarthritis (OA). Late-breaking abstracts. Program and abstracts of American College of Rheumatology 67th Annual Scientific Meeting, Orlando (FL), October 23–28, 2003

Chen, 2003, Time, stress, and location dependent chondrocyte death and collagen damage in cyclically loaded articular cartilage, J Orthop Res, 21, 888, 10.1016/S0736-0266(03)00050-0

Lucchinetti, 2002, Cartilage viability after repetitive loading: a preliminary report, Osteoarthritis Cartilage, 10, 71, 10.1053/joca.2001.0483

Lin, 2004, Increased stromelysin-1 (MMP-3), proteoglycan degradation (3B3- and 7D4) and collagen damage in cyclically load-injured articular cartilage, Osteoarthritis Cartilage, 12, 485, 10.1016/j.joca.2004.02.012

Sakkas, 1998, T cells and T-cell cytokine transcripts in the synovial membrane in patients with osteoarthritis, Clin Diagn Lab Immunol, 5, 430, 10.1128/CDLI.5.4.430-437.1998

Moos, 1999, Immunohistological analysis of cytokine expression in human osteoarthritic and healthy cartilage, J Rheumatol, 26, 870

Caron, 1996, Chondroprotective effect of intraarticular injections of interleukin-1 receptor antagonist in experimental osteoarthritis. Suppression of collagenase-1 expression, Arthritis Rheum, 39, 1535, 10.1002/art.1780390914

van de Loo, 1995, Role of interleukin-1, tumor necrosis factor alpha, and interleukin-6 in cartilage proteoglycan metabolism and destruction. Effect of in situ blocking in murine antigen- and zymosan-induced arthritis, Arthritis Rheum, 38, 164, 10.1002/art.1780380204

Kaneyama, 2002, Importance of proinflammatory cytokines in synovial fluid from 121 joints with temporomandibular disorders, Br J Oral Maxillofac Surg, 40, 418, 10.1016/S0266-4356(02)00215-2

Segami, 2002, Does joint effusion on T2 magnetic resonance images reflect synovitis? Part 2. Comparison of concentration levels of proinflammatory cytokines and total protein in synovial fluid of the temporomandibular joint with internal derangements and osteoarthrosis, Oral Surg Oral Med Oral Pathol Oral Radiol Endod, 94, 515, 10.1067/moe.2002.126697

Nishimura, 2002, Proinflammatory cytokines and arthroscopic findings of patients with internal derangement and osteoarthritis of the temporomandibular joint, Br J Oral Maxillofac Surg, 40, 68, 10.1054/bjom.2001.0742

Dougados, 2001, Evaluation of the structure-modifying effects of diacerein in hip osteoarthritis: ECHODIAH, a three-year, placebo-controlled trial. Evaluation of the Chondromodulating Effect of Diacerein in OA of the Hip, Arthritis Rheum, 44, 2539, 10.1002/1529-0131(200111)44:11<2539::AID-ART434>3.0.CO;2-T

Bathon, 2000, A comparison of etanercept and methotrexate in patients with early rheumatoid arthritis, N Engl J Med, 343, 1586, 10.1056/NEJM200011303432201

Genovese, 2002, Etanercept versus methotrexate in patients with early rheumatoid arthritis: two-year radiographic and clinical outcomes, Arthritis Rheum, 46, 1443, 10.1002/art.10308

Yokota, 2003, Interleukin 6 as a therapeutic target in systemic-onset juvenile idiopathic arthritis, Curr Opin Rheumatol, 15, 581, 10.1097/00002281-200309000-00010

Iwamoto, 2002, Humanized monoclonal anti-interleukin-6 receptor antibody for treatment of intractable adult-onset Still's disease, Arthritis Rheum, 46, 3388, 10.1002/art.10620

Wolfe, 1997, The C-reactive protein but not erythrocyte sedimentation rate is associated with clinical severity in patients with osteoarthritis of the knee or hip, J Rheumatol, 24, 1486

Sharif, 1997, Elevated serum C-reactive protein levels in osteoarthritis, Br J Rheumatol, 36, 140, 10.1093/rheumatology/36.1.140

Otterness, 2000, An analysis of 14 molecular markers for monitoring osteoarthritis: segregation of the markers into clusters and distinguishing osteoarthritis at baseline, Osteoarthritis Cartilage, 8, 180, 10.1053/joca.1999.0288

Conrozier, 2000, Serum levels of YKL-40 and C reactive protein in patients with hip osteoarthritis and healthy subjects: a cross sectional study [in process citation], Ann Rheum Dis, 59, 828, 10.1136/ard.59.10.828

Conrozier, 1998, Increased serum C-reactive protein levels by immunonephelometry in patients with rapidly destructive hip osteoarthritis, Rev Rhum Engl Ed, 65, 759

Spector, 1997, Low-level increases in serum C-reactive protein are present in early osteoarthritis of the knee and predict progressive disease, Arthritis Rheum, 40, 723, 10.1002/art.1780400419

Sharif, 2000, Increased serum C reactive protein may reflect events that precede radiographic progression in osteoarthritis of the knee, Ann Rheum Dis, 59, 71, 10.1136/ard.59.1.71

Sowers, 2002, C-reactive protein as a biomarker of emergent osteoarthritis, Osteoarthritis Cartilage, 10, 595, 10.1053/joca.2002.0800