Baricitinib and primary biliary cholangitis

Journal of Translational Autoimmunity - Tập 4 - Trang 100107 - 2021
Stuart C. Gordon1,2, Sheri Trudeau3, Arie Regev4, Jonathan M. Uhas1, Sujatro Chakladar4, Ana Pinto-Correia4, Klaus Gottlieb4, Doug Schlichting4
1Division of Gastroenterology and Hepatology, Henry Ford Health System, Detroit, MI, USA
2Wayne State University School of Medicine, Detroit, MI, USA
3Department of Public Health Sciences, Henry Ford Health System, Detroit, MI, USA
4Eli Lilly & Company, Indianapolis, IN, USA.

Tài liệu tham khảo

Kaplan, 2005, Primary biliary cirrhosis, N. Engl. J. Med., 353, 1261, 10.1056/NEJMra043898 Lindor, 2009, Primary biliary cirrhosis, Hepatology, 50, 291, 10.1002/hep.22906 Kuiper, 2009, Improved prognosis of patients with primary biliary cirrhosis that have a biochemical response to ursodeoxycholic acid, Gastroenterology, 136, 1281, 10.1053/j.gastro.2009.01.003 Pares, 2006, Excellent long‐term survival in patients with primary biliary cirrhosis and biochemical response to ursodeoxycholic Acid, Gastroenterology, 130, 715, 10.1053/j.gastro.2005.12.029 Corpechot, 2008, Biochemical response to ursodeoxycholic acid and long‐term prognosis in primary biliary cirrhosis, Hepatology, 48, 871, 10.1002/hep.22428 Hirschfield, 2015, Efficacy of obeticholic acid in patients with primary biliary cirrhosis and inadequate response to ursodeoxycholic acid, Gastroenterology, 148, 751, 10.1053/j.gastro.2014.12.005 2016 Dyson, 2016, The inter‐relationship of symptom severity and quality of life in 2055 patients with primary biliary cholangitis, Aliment. Pharmacol. Ther., 44, 1039, 10.1111/apt.13794 Fuchs, 2017, Novel treatments targeting metabolic and signaling mechanisms in primary biliary cholangitis, Clin. Liver Dis., 9, 43, 10.1002/cld.613 Papp, 2016, A randomized phase 2b trial of baricitinib, an oral Janus kinase (JAK) 1/JAK2 inhibitor, in patients with moderate‐to‐severe psoriasis, Br. J. Dermatol., 174, 1266, 10.1111/bjd.14403 Blome, 2012, Assessment of pruritus intensity: prospective study on validity and reliability of the visual analogue scale, numerical rating scale and verbal rating scale in 471 patients with chronic pruritus, Acta Derm. Venereol., 92, 502, 10.2340/00015555-1246 Neuberge, 2003, Measures of fatigue: the fatigue questionnaire, fatigue severity scale, multidimensional assessment of fatigue scale, and short form‐36 vitality (Energy/Fatigue) subscale of the short form Health survey, Arthritis Rheum., 49, S175, 10.1002/art.11405 Phan, 2012, Assessment of pruritus intensity: prospective study on validity and reliability of the visual analogue scale, numerical rating scale and verbal rating scale in 471 patients with chronic pruritus, Acta Derm. Venereol., 92, 502, 10.2340/00015555-1246 Lichtinghagen, 2013, The Enhanced Liver Fibrosis (ELF) score: normal values, influence factors and proposed cut-off values, J. Hepatol., 59, 236, 10.1016/j.jhep.2013.03.016 Rush, 2003, The 16-Item Quick Inventory of Depressive Symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression, Biol. Psychiatr., 54, 573, 10.1016/S0006-3223(02)01866-8 Hirschfield, 2009, Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants, N. Engl. J. Med., 360, 2544, 10.1056/NEJMoa0810440 Kawata, 2013, Identification of potential cytokine pathways for therapeutic intervention in murine primary biliary cirrhosis, PloS One, 8, 10.1371/journal.pone.0074225 Fridman, 2010, Selective inhibition of JAK1 and JAK2 is efficacious in rodent models of arthritis: preclinical characterization of INCB028050, J. Immunol., 184, 5298, 10.4049/jimmunol.0902819 O'Shea, 2015, The JAK-STAT pathway: impact on human disease and therapeutic intervention, Annu. Rev. Med., 66, 311, 10.1146/annurev-med-051113-024537 O'Shea, 2013, Janus kinase inhibitors in autoimmune diseases, Ann. Rheum. Dis., 72, ii111, 10.1136/annrheumdis-2012-202576 Poupon, 1996, Primary biliary cirrhosis, 1329