BMI1 promotes spermatogonial stem cell maintenance by epigenetically repressing Wnt10b/β-catenin signaling

International Journal of Biological Sciences - Tập 18 Số 7 - Trang 2807-2820 - 2022
Jun Yu1, Cong Shen2, Meng Lin3, Xia Chen4, Xiuliang Dai5, Zhi‐Ran Li1, Yunhao Wu1, Yangbo Fu1, Jinxing Lv6, Xiaoyan Huang3, Bo Zheng7,2, Fei Sun1
1Institute of Reproductive Medicine, School of Medicine, Nantong University, Nantong, 226001, China
2State Key Laboratory of Reproductive Medicine, Center for Reproduction and Genetics, Suzhou Municipal Hospital, The Affiliated Suzhou Hospital of Nanjing Medical University, Gusu School, Nanjing Medical University, Suzhou, 215002, China
3State Key Laboratory of Reproductive Medicine, Department of Histology and Embryology, Nanjing Medical University, Nanjing 211166, China
4. Department of Obstetrics and Gynecology, Affiliated Hospital 2 of Nantong University and First People's Hospital of Nantong City, Nantong 226001, China.
5. Center of Clinical Reproductive Medicine, The Affiliated Changzhou Maternity and Child Health Care Hospital of Nanjing Medical University, Changzhou 213000, China.
6. Suzhou Dushu Lake Hospital (Dushu Lake Hospital Affiliated to Soochow University), Suzhou 215124, China.
7NHC Key Laboratory of Study on Abnormal Gametes and Reproductive Tract, Anhui Medical University, Hefei 230032, China

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