BAG3 Regulation of RAB35 Mediates the Endosomal Sorting Complexes Required for Transport/Endolysosome Pathway and Tau Clearance
Tài liệu tham khảo
Hipp, 2019, The proteostasis network and its decline in ageing, Nat Rev Mol Cell Biol, 20, 421, 10.1038/s41580-019-0101-y
Kurtishi, 2019, Cellular proteostasis in neurodegeneration, Mol Neurobiol, 56, 3676, 10.1007/s12035-018-1334-z
Long, 2019, Alzheimer disease: An update on pathobiology and treatment strategies, Cell, 179, 312, 10.1016/j.cell.2019.09.001
Chen, 2019, Alzheimer disease pathogenesis: Insights from molecular and cellular biology studies of oligomeric Aβ and tau species, Front Neurosci, 13, 659, 10.3389/fnins.2019.00659
Nixon, 2020, The aging lysosome: An essential catalyst for late-onset neurodegenerative diseases, Biochim Biophys Acta Proteins Proteom, 1868, 140443, 10.1016/j.bbapap.2020.140443
Jiang, 2019, Lysosomal dysfunction in Down syndrome is APP-dependent and mediated by APP-βCTF (C99), J Neurosci, 39, 5255, 10.1523/JNEUROSCI.0578-19.2019
Winckler, 2018, The endolysosomal system and proteostasis: From development to degeneration, J Neurosci, 38, 9364, 10.1523/JNEUROSCI.1665-18.2018
Pensalfini, 2020, Endosomal dysfunction induced by directly overactivating Rab5 recapitulates prodromal and neurodegenerative features of Alzheimer’s disease, Cell Rep, 33, 108420, 10.1016/j.celrep.2020.108420
Majumder, 2016, ESCRTs and associated proteins in lysosomal fusion with endosomes and autophagosomes, Biochem Cell Biol, 94, 443, 10.1139/bcb-2016-0099
Hu, 2015, The endosomal-lysosomal system: From acidification and cargo sorting to neurodegeneration, Transl Neurodegener, 4, 18, 10.1186/s40035-015-0041-1
Cataldo, 2000, Endocytic pathway abnormalities precede amyloid beta deposition in sporadic Alzheimer’s disease and Down syndrome: Differential effects of APOE genotype and presenilin mutations, Am J Pathol, 157, 277, 10.1016/S0002-9440(10)64538-5
Tang, 2018, Nrf2 mediates the expression of BAG3 and autophagy cargo adaptor proteins and tau clearance in an age-dependent manner, Neurobiol Aging, 63, 128, 10.1016/j.neurobiolaging.2017.12.001
Behl, 2016, Breaking BAG: The co-chaperone BAG3 in health and disease, Trends Pharmacol Sci, 37, 672, 10.1016/j.tips.2016.04.007
Stürner, 2017, The role of the multifunctional BAG3 protein in cellular protein quality control and in disease, Front Mol Neurosci, 10, 177, 10.3389/fnmol.2017.00177
Zhou, 2020, Cyclin-dependent kinase 5-dependent BAG3 degradation modulates synaptic protein turnover, Biol Psychiatry, 87, 756, 10.1016/j.biopsych.2019.11.013
Chakraborty, 2019, Enhanced autophagic-lysosomal activity and increased BAG3-mediated selective macroautophagy as adaptive response of neuronal cells to chronic oxidative stress, Redox Biol, 24, 101181, 10.1016/j.redox.2019.101181
Lin, 2022, The role of BAG3 in health and disease: A “Magic BAG of Tricks”, J Cell Biochem, 123, 4, 10.1002/jcb.29952
Fu, 2019, A tau homeostasis signature is linked with the cellular and regional vulnerability of excitatory neurons to tau pathology, Nat Neurosci, 22, 47, 10.1038/s41593-018-0298-7
Lei, 2015, BAG3 facilitates the clearance of endogenous tau in primary neurons, Neurobiol Aging, 36, 241, 10.1016/j.neurobiolaging.2014.08.012
Cao, 2017, A role of BAG3 in regulating SNCA/α-synuclein clearance via selective macroautophagy, Neurobiol Aging, 60, 104, 10.1016/j.neurobiolaging.2017.08.023
Hsu, 2010, Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C, J Cell Biol, 189, 223, 10.1083/jcb.200911018
Hanono, 2006, EPI64 regulates microvillar subdomains and structure, J Cell Biol, 175, 803, 10.1083/jcb.200604046
Klinkert, 2016, Rab35 GTPase: A central regulator of phosphoinositides and F-actin in endocytic recycling and beyond, Traffic, 17, 1063, 10.1111/tra.12422
Mignogna, 2018, Critical importance of RAB proteins for synaptic function, Small GTPases, 9, 145, 10.1080/21541248.2016.1277001
Sheehan, 2019, Coordination of synaptic vesicle trafficking and turnover by the Rab35 signaling network, Small GTPases, 10, 54, 10.1080/21541248.2016.1270392
Vaz-Silva, 2018, Endolysosomal degradation of Tau and its role in glucocorticoid-driven hippocampal malfunction, EMBO J, 37, 10.15252/embj.201899084
Ji, 2019, BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes, Autophagy, 15, 1199, 10.1080/15548627.2019.1580096
Granger, 2014, The role of the cytoskeleton and molecular motors in endosomal dynamics, Semin Cell Dev Biol, 31, 20, 10.1016/j.semcdb.2014.04.011
Wandinger-Ness, 2014, Rab proteins and the compartmentalization of the endosomal system, Cold Spring Harb Perspect Biol, 6, a022616, 10.1101/cshperspect.a022616
Chesneau, 2012, An ARF6/Rab35 GTPase cascade for endocytic recycling and successful cytokinesis, Curr Biol, 22, 147, 10.1016/j.cub.2011.11.058
Sheehan, 2016, Activity-dependent degradation of synaptic vesicle proteins requires Rab35 and the ESCRT pathway, J Neurosci, 36, 8668, 10.1523/JNEUROSCI.0725-16.2016
Aaron, 2018, Image co-localization—Co-occurrence versus correlation, J Cell Sci, 131, jcs211847, 10.1242/jcs.211847
Fuchs, 2009, Identification of the key structural motifs involved in HspB8/HspB6-Bag3 interaction [published correction appears in Biochem J 2010; 430:559], Biochem J, 425, 245, 10.1042/BJ20090907
Carra, 2008, HspB8 chaperone activity toward poly(Q)-containing proteins depends on its association with Bag3, a stimulator of macroautophagy, J Biol Chem, 283, 1437, 10.1074/jbc.M706304200
Ulbricht, 2013, Cellular mechanotransduction relies on tension-induced and chaperone-assisted autophagy, Curr Biol, 23, 430, 10.1016/j.cub.2013.01.064
Doong, 2003, CAIR-1/BAG-3 abrogates heat shock protein-70 chaperone complex-mediated protein degradation: Accumulation of poly-ubiquitinated Hsp90 client proteins, J Biol Chem, 278, 28490, 10.1074/jbc.M209682200
Arimura, 2011, Dilated cardiomyopathy-associated BAG3 mutations impair Z-disc assembly and enhance sensitivity to apoptosis in cardiomyocytes, Hum Mutat, 32, 1481, 10.1002/humu.21603
Li, 2015, Validation of the Hsp70-Bag3 protein-protein interaction as a potential therapeutic target in cancer, Mol Cancer Ther, 14, 642, 10.1158/1535-7163.MCT-14-0650
Fuchs, 2015, A role for the chaperone complex BAG3-HSPB8 in actin dynamics, spindle orientation and proper chromosome segregation during mitosis, PLoS Genet, 11, 10.1371/journal.pgen.1005582
Rivera-Molina, 2009, A Rab GAP cascade defines the boundary between two Rab GTPases on the secretory pathway, Proc Natl Acad Sci U S A, 106, 14408, 10.1073/pnas.0906536106
Zhen, 2015, Cellular functions of Rab GTPases at a glance, J Cell Sci, 128, 3171
Nottingham, 2009, Defining the boundaries: Rab GEFs and GAPs, Proc Natl Acad Sci U S A, 106, 14185, 10.1073/pnas.0907725106
Kobayashi, 2015, Measurement of Rab35 activity with the GTP-Rab35 trapper RBD35, Methods Mol Biol, 1298, 207, 10.1007/978-1-4939-2569-8_18
Hokanson, 2012, EPI64 interacts with Slp1/JFC1 to coordinate Rab8a and Arf6 membrane trafficking, Mol Biol Cell, 23, 701, 10.1091/mbc.e11-06-0521
Hou, 2013, EPI64B acts as a GTPase-activating protein for Rab27B in pancreatic acinar cells, J Biol Chem, 288, 19548, 10.1074/jbc.M113.472134
Skibinski, 2005, Mutations in the endosomal ESCRTIII-complex subunit CHMP2B in frontotemporal dementia, Nat Genet, 37, 806, 10.1038/ng1609
Wenzel, 2018, Concerted ESCRT and clathrin recruitment waves define the timing and morphology of intraluminal vesicle formation, Nat Commun, 9, 2932, 10.1038/s41467-018-05345-8
Bache, 2003, Hrs regulates multivesicular body formation via ESCRT recruitment to endosomes, J Cell Biol, 162, 435, 10.1083/jcb.200302131
Yoshiyama, 2007, Synapse loss and microglial activation precede tangles in a P301S tauopathy mouse model [published correction appears in Neuron 2007; 54:343–344], Neuron, 53, 337, 10.1016/j.neuron.2007.01.010
Makani, 2016, Evaluation of the brain-penetrant microtubule-stabilizing agent, dictyostatin, in the PS19 tau transgenic mouse model of tauopathy, Acta Neuropathol Commun, 4, 106, 10.1186/s40478-016-0378-4
Zhang, 2012, The microtubule-stabilizing agent, epothilone D, reduces axonal dysfunction, neurotoxicity, cognitive deficits, and Alzheimer-like pathology in an interventional study with aged tau transgenic mice, J Neurosci, 32, 3601, 10.1523/JNEUROSCI.4922-11.2012
Clavaguera, 2009, Transmission and spreading of tauopathy in transgenic mouse brain, Nat Cell Biol, 11, 909, 10.1038/ncb1901
Johnson, 1997, The tau protein in human cerebrospinal fluid in Alzheimer’s disease consists of proteolytically derived fragments, J Neurochem, 68, 430, 10.1046/j.1471-4159.1997.68010430.x
Lasagna-Reeves, 2012, Identification of oligomers at early stages of tau aggregation in Alzheimer’s disease, FASEB J, 26, 1946, 10.1096/fj.11-199851
Jicha, 1997, Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau, J Neurosci Res, 48, 128, 10.1002/(SICI)1097-4547(19970415)48:2<128::AID-JNR5>3.0.CO;2-E
Hunt, 1996, PSD-95 is associated with the postsynaptic density and not with the presynaptic membrane at forebrain synapses, J Neurosci, 16, 1380, 10.1523/JNEUROSCI.16-04-01380.1996
Bernhardt, 1984, Light and electron microscopic studies of the distribution of microtubule-associated protein 2 in rat brain: A difference between dendritic and axonal cytoskeletons, J Comp Neurol, 226, 203, 10.1002/cne.902260205
Klaips, 2018, Pathways of cellular proteostasis in aging and disease, J Cell Biol, 217, 51, 10.1083/jcb.201709072
Krüger, 2016, Tau neurotoxicity and rescue in animal models of human Tauopathies, Curr Opin Neurobiol, 36, 52, 10.1016/j.conb.2015.09.004
Yin, 2016, Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling, Proc Natl Acad Sci U S A, 113, E3773, 10.1073/pnas.1604519113
Kimura, 2007, Hyperphosphorylated tau in parahippocampal cortex impairs place learning in aged mice expressing wild-type human tau, EMBO J, 26, 5143, 10.1038/sj.emboj.7601917
Jadhav, 2019, A walk through tau therapeutic strategies, Acta Neuropathol Commun, 7, 22, 10.1186/s40478-019-0664-z
Suzuki, 2011, BAG3 (BCL2-associated athanogene 3) interacts with MMP-2 to positively regulate invasion by ovarian carcinoma cells, Cancer Lett, 303, 65, 10.1016/j.canlet.2011.01.019
Feldman, 2016, BAG3 regulates contractility and Ca(2+) homeostasis in adult mouse ventricular myocytes, J Mol Cell Cardiol, 92, 10, 10.1016/j.yjmcc.2016.01.015
Chen, 2013, Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity, Mol Cell Proteomics, 12, 2804, 10.1074/mcp.M112.025882
Sondermann, 2001, Structure of a Bag/Hsc70 complex: Convergent functional evolution of Hsp70 nucleotide exchange factors, Science, 291, 1553, 10.1126/science.1057268
Kouranti, 2006, Rab35 regulates an endocytic recycling pathway essential for the terminal steps of cytokinesis, Curr Biol, 16, 1719, 10.1016/j.cub.2006.07.020
Chevallier, 2009, Rab35 regulates neurite outgrowth and cell shape, FEBS Lett, 583, 1096, 10.1016/j.febslet.2009.03.012
Cauvin, 2016, Rab35 GTPase triggers switch-like recruitment of the Lowe syndrome lipid phosphatase OCRL on newborn endosomes, Curr Biol, 26, 120, 10.1016/j.cub.2015.11.040
Um, 2016, IQ motif and SEC7 domain-containing protein 3 (IQSEC3) interacts with gephyrin to promote inhibitory synapse formation, J Biol Chem, 291, 10119, 10.1074/jbc.M115.712893
Frankel, 2018, ESCRT-dependent cargo sorting at multivesicular endosomes, Semin Cell Dev Biol, 74, 4, 10.1016/j.semcdb.2017.08.020
Yamashita, 2008, Ubiquitin-independent binding of Hrs mediates endosomal sorting of the interleukin-2 receptor beta-chain, J Cell Sci, 121, 1727, 10.1242/jcs.024455