Azathioprine and inhibition of the anticoagulant effect of warfarin: Evidence from a case report and a literature review

Heng Joo Ng1,2, Mark A. Crowther1
1St. Joseph's Hospital, McMaster University Faculty of Health Sciences, Hamilton, Ontario, Canada
2Department of Haematology, Singapore General Hospital, Singapore

Tài liệu tham khảo

Singleton, 1992, Warfarin and azathioprine: An important drug interaction, Am J Med, 92, 217, 10.1016/0002-9343(92)90116-S Rivier, 1993, Warfarin and azathioprine: A drug interaction does exist, Am J Med, 95, 342, 10.1016/0002-9343(93)90292-W Havrda, 2001, A case report of warfarm resistance due to azathioprine and review of the literature, Pharmacotherapy, 21, 355, 10.1592/phco.21.3.355.34208 Rotenberg, 2000, Effect of azathioprine on the anticoagulant activity of warfarin, Ann Pharmacother, 34, 120, 10.1345/aph.19088 Walker, 2002, Warfarin and azathioprine: Clinically significant drug interaction, J Rheumatol, 29, 398 Wells, 1994, Interactions of warfarin with drugs and food, Ann Intern Med, 121, 676, 10.7326/0003-4819-121-9-199411010-00009 Castellino, 2001, Characteristics of patients with antiphospholipid syndrome with major bleeding after oral anticoagulant treatment, Ann Rheum Dis, 60, 527, 10.1136/ard.60.5.527 Spiers, 1974, Letter: Increased warfarin requirement during mercaptopurine therapy: A new drug interaction, Lancet, 2, 221, 10.1016/S0140-6736(74)91523-2 Fernandez, 1999, Acenocoumarol and 6-mercaptopurine: An important drug interaction, Haematologica, 84, 664 Naranjo, 1981, A method for estimating the probability of adverse drug reactions, Clin Pharmacol Ther, 30, 239, 10.1038/clpt.1981.154