Axillary Granular Parakeratosis

Joseph C. English1, Amalie S. Derdeyn1, Wendy M. Wilson1, James W. Patterson1
1Department of Dermatology and Pathology, University of Virginia Health System, Charlottesville, Virginia, USA

Tóm tắt

Background: Granular parakeratosis is a hyperkeratotic eruption of unknown etiology that occurs in the axilla and other intertriginous areas. The histologic features are unique for the retention of keratohyalin granules in the stratum corneum. Objective: The aim of the article is to review the clinical manifestations and treatment of granular parakeratosis. Methods: A case report and literature review are presented. Results: Twenty-six cases of granular parakeratosis now have been reported and reviewed. Conclusion: Granular parakeratosis occurs predominantly in middle age women and most frequently in the axilla. A number of treatments have been applied to the 26 cases reported to date, without consistent responses. No evidence-based therapy can be suggested at present.

Tài liệu tham khảo

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