Autophagy and the Integrated Stress Response
Tóm tắt
Từ khóa
Tài liệu tham khảo
Alexander, 2010, ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS, Proc. Natl. Acad. Sci. USA, 107, 4153, 10.1073/pnas.0913860107
Axe, 2008, Autophagosome formation from membrane compartments enriched in phosphatidylinositol 3-phosphate and dynamically connected to the endoplasmic reticulum, J. Cell Biol., 182, 685, 10.1083/jcb.200803137
Baud, 2009, Is NF-kappaB a good target for cancer therapy? Hopes and pitfalls, Nat. Rev. Drug Discov., 8, 33, 10.1038/nrd2781
Behrends, 2010, Network organization of the human autophagy system, Nature, 466, 68, 10.1038/nature09204
Bellot, 2009, Hypoxia-induced autophagy is mediated through hypoxia-inducible factor induction of BNIP3 and BNIP3L via their BH3 domains, Mol. Cell. Biol., 29, 2570, 10.1128/MCB.00166-09
Bensaad, 2009, Modulation of intracellular ROS levels by TIGAR controls autophagy, EMBO J., 28, 3015, 10.1038/emboj.2009.242
Betin, 2009, Caspase cleavage of Atg4D stimulates GABARAP-L1 processing and triggers mitochondrial targeting and apoptosis, J. Cell Sci., 122, 2554, 10.1242/jcs.046250
Bonnet, 2000, PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex, Mol. Cell. Biol., 20, 4532, 10.1128/MCB.20.13.4532-4542.2000
Boya, 2005, Inhibition of macroautophagy triggers apoptosis, Mol. Cell. Biol., 25, 1025, 10.1128/MCB.25.3.1025-1040.2005
Buchberger, 2010, Protein quality control in the cytosol and the endoplasmic reticulum: brothers in arms, Mol. Cell, 40, 238, 10.1016/j.molcel.2010.10.001
Copetti, 2009, p65/RelA modulates BECN1 transcription and autophagy, Mol. Cell. Biol., 29, 2594, 10.1128/MCB.01396-08
Criollo, 2010, The IKK complex contributes to the induction of autophagy, EMBO J., 29, 619, 10.1038/emboj.2009.364
Deng, 2004, Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2, Mol. Cell. Biol., 24, 10161, 10.1128/MCB.24.23.10161-10168.2004
Di Bartolomeo, 2010, The dynamic interaction of Ambra1 with the dynein motor complex regulates mammalian autophagy, J. Cell Biol., 191, 155, 10.1083/jcb.201002100
Efeyan, 2010, mTOR and cancer: many loops in one pathway, Curr. Opin. Cell Biol., 22, 169, 10.1016/j.ceb.2009.10.007
Eisenberg, 2009, Induction of autophagy by spermidine promotes longevity, Nat. Cell Biol., 11, 1305, 10.1038/ncb1975
Furuya, 2010, Negative regulation of Vps34 by Cdk mediated phosphorylation, Mol. Cell, 38, 500, 10.1016/j.molcel.2010.05.009
Gan, 2008, FIP200, a key signaling node to coordinately regulate various cellular processes, Cell. Signal., 20, 787, 10.1016/j.cellsig.2007.10.021
Geisler, 2010, PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1, Nat. Cell Biol., 12, 119, 10.1038/ncb2012
Green, 2009, Cytoplasmic functions of the tumour suppressor p53, Nature, 458, 1127, 10.1038/nature07986
Gutierrez, 2004, Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages, Cell, 119, 753, 10.1016/j.cell.2004.11.038
Haigis, 2010, Mammalian sirtuins: biological insights and disease relevance, Annu. Rev. Pathol., 5, 253, 10.1146/annurev.pathol.4.110807.092250
Hailey, 2010, Mitochondria supply membranes for autophagosome biogenesis during starvation, Cell, 141, 656, 10.1016/j.cell.2010.04.009
Harding, 2003, An integrated stress response regulates amino acid metabolism and resistance to oxidative stress, Mol. Cell, 11, 619, 10.1016/S1097-2765(03)00105-9
Harrison, 2008, DAPK-1 binding to a linear peptide motif in MAP1B stimulates autophagy and membrane blebbing, J. Biol. Chem., 283, 9999, 10.1074/jbc.M706040200
Hayashi-Nishino, 2009, A subdomain of the endoplasmic reticulum forms a cradle for autophagosome formation, Nat. Cell Biol., 11, 1433, 10.1038/ncb1991
He, 2009, Regulation mechanisms and signaling pathways of autophagy, Annu. Rev. Genet., 43, 67, 10.1146/annurev-genet-102808-114910
Herrero-Martin, 2009, TAK1 activates AMPK-dependent cytoprotective autophagy in TRAIL-treated epithelial cells, EMBO J., 28, 677, 10.1038/emboj.2009.8
Hetz, 2009, Fine-tuning of the unfolded protein response: assembling the IRE1alpha interactome, Mol. Cell, 35, 551, 10.1016/j.molcel.2009.08.021
Hetz, 2009, XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy, Genes Dev., 23, 2294, 10.1101/gad.1830709
Hotamisligil, 2010, Endoplasmic reticulum stress and the inflammatory basis of metabolic disease, Cell, 140, 900, 10.1016/j.cell.2010.02.034
Huang, 2009, A novel function of poly(ADP-ribose) polymerase-1 in modulation of autophagy and necrosis under oxidative stress, Cell Death Differ., 16, 264, 10.1038/cdd.2008.151
Kimball, 2003, Mammalian stress granules represent sites of accumulation of stalled translation initiation complexes, Am. J. Physiol. Cell Physiol., 284, C273, 10.1152/ajpcell.00314.2002
Kirkin, 2009, A role for ubiquitin in selective autophagy, Mol. Cell, 34, 259, 10.1016/j.molcel.2009.04.026
Komatsu, 2010, The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1, Nat. Cell Biol., 12, 213, 10.1038/ncb2021
Kouroku, 2007, ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation, Cell Death Differ., 14, 230, 10.1038/sj.cdd.4401984
Kroemer, 2007, Mitochondrial membrane permeabilization in cell death, Physiol. Rev., 87, 99, 10.1152/physrev.00013.2006
Kume, 2010, Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney, J. Clin. Invest., 120, 1043, 10.1172/JCI41376
Lan, 2008, SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation, J. Biol. Chem., 283, 27628, 10.1074/jbc.M805711200
Lee, 2008, A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy, Proc. Natl. Acad. Sci. USA, 105, 3374, 10.1073/pnas.0712145105
Lee, 2009, Regulation of autophagy by the p300 acetyltransferase, J. Biol. Chem., 284, 6322, 10.1074/jbc.M807135200
Lee, 2009, FLIP-mediated autophagy regulation in cell death control, Nat. Cell Biol., 11, 1355, 10.1038/ncb1980
Lee, 2010, HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy, EMBO J., 29, 969, 10.1038/emboj.2009.405
Liang, 2007, The energy sensing LKB1-AMPK pathway regulates p27(kip1) phosphorylation mediating the decision to enter autophagy or apoptosis, Nat. Cell Biol., 9, 218, 10.1038/ncb1537
Lipinski, 2010, A genome-wide siRNA screen reveals multiple mTORC1 independent signaling pathways regulating autophagy under normal nutritional conditions, Dev. Cell, 18, 1041, 10.1016/j.devcel.2010.05.005
Liu, 2008, Hypoxic reactive oxygen species regulate the integrated stress response and cell survival, J. Biol. Chem., 283, 31153, 10.1074/jbc.M805056200
Madeo, 2010, Does autophagy induction prolong longevity?, Nat. Cell Biol., 11, 942
Maiuri, 2007, Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1, EMBO J., 26, 2527, 10.1038/sj.emboj.7601689
Majmundar, 2010, Hypoxia-inducible factors and the response to hypoxic stress, Mol. Cell, 40, 294, 10.1016/j.molcel.2010.09.022
Mammucari, 2007, FoxO3 controls autophagy in skeletal muscle in vivo, Cell Metab., 6, 458, 10.1016/j.cmet.2007.11.001
Mathew, 2009, Autophagy suppresses tumorigenesis through elimination of p62, Cell, 137, 1062, 10.1016/j.cell.2009.03.048
Mazure, 2010, Hypoxia-induced autophagy: cell death or cell survival?, Curr. Opin. Cell Biol., 22, 177, 10.1016/j.ceb.2009.11.015
Michiorri, 2010, The Parkinson-associated protein PINK1 interacts with Beclin1 and promotes autophagy, Cell Death Differ., 17, 962, 10.1038/cdd.2009.200
Milani, 2009, The role of ATF4 stabilization and autophagy in resistance of breast cancer cells treated with Bortezomib, Cancer Res., 69, 4415, 10.1158/0008-5472.CAN-08-2839
Mizushima, 2010, The role of the Atg1/ULK1 complex in autophagy regulation, Curr. Opin. Cell Biol., 22, 132, 10.1016/j.ceb.2009.12.004
Mizushima, 2008, Autophagy fights disease through cellular self-digestion, Nature, 451, 1069, 10.1038/nature06639
Mizushima, 2010, Methods in mammalian autophagy research, Cell, 140, 313, 10.1016/j.cell.2010.01.028
Morselli, 2010, Caloric restriction and resveratrol prolong longevity via the sirtuin-1 dependent induction of autophagy, Cell Death Disease, 1, e10, 10.1038/cddis.2009.8
Nakamura, 2010, Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis, Cell, 140, 338, 10.1016/j.cell.2010.01.001
Narendra, 2010, PINK1 is selectively stabilized on impaired mitochondria to activate Parkin, PLoS Biol., 8, e1000298, 10.1371/journal.pbio.1000298
Nasrin, 2009, JNK1 phosphorylates SIRT1 and promotes its enzymatic activity, PLoS ONE, 4, e8414, 10.1371/journal.pone.0008414
Neufeld, 2010, TOR-dependent control of autophagy: biting the hand that feeds, Curr. Opin. Cell Biol., 22, 157, 10.1016/j.ceb.2009.11.005
Nivon, 2009, Autophagy activation by NFkappaB is essential for cell survival after heat shock, Autophagy, 5, 766, 10.4161/auto.8788
Novak, 2010, Nix is a selective autophagy receptor for mitochondrial clearance, EMBO Rep., 11, 45, 10.1038/embor.2009.256
Orsi, 2010, Membrane trafficking events that partake in autophagy, Curr. Opin. Cell Biol., 22, 150, 10.1016/j.ceb.2009.11.013
Pattingre, 2005, Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy, Cell, 122, 927, 10.1016/j.cell.2005.07.002
Pattingre, 2009, Role of JNK1-dependent Bcl-2 phosphorylation in ceramide-induced macroautophagy, J. Biol. Chem., 284, 2719, 10.1074/jbc.M805920200
Polson, 2010, Mammalian Atg18 (WIPI2) localizes to omegasome-anchored phagophores and positively regulates LC3 lipidation, Autophagy, 6, 10.4161/auto.6.4.11863
Qing, 2007, Hsp90 regulates processing of NF-kappa B2 p100 involving protection of NF-kappa B-inducing kinase (NIK) from autophagy-mediated degradation, Cell Res., 17, 520, 10.1038/cr.2007.47
Ravikumar, 2010, Plasma membrane contributes to the formation of pre-autophagosomal structures, Nat. Cell Biol., 12, 747, 10.1038/ncb2078
Rouschop, 2010, The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5, J. Clin. Invest., 120, 127, 10.1172/JCI40027
Ruderman, 2010, AMPK and SIRT1: a long-standing partnership?, Am. J. Physiol. Endocrinol. Metab., 298, E751, 10.1152/ajpendo.00745.2009
Saitoh, 2009, Atg9a controls dsDNA-driven dynamic translocation of STING and the innate immune response, Proc. Natl. Acad. Sci. USA, 106, 10842, 10.1073/pnas.0911267106
Sandoval, 2008, Essential role for Nix in autophagic maturation of erythroid cells, Nature, 454, 232, 10.1038/nature07006
Sarkar, 2007, Small molecules enhance autophagy and reduce toxicity in Huntington's disease models, Nat. Chem. Biol., 3, 331, 10.1038/nchembio883
Scherz-Shouval, 2007, Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4, EMBO J., 26, 1749, 10.1038/sj.emboj.7601623
Sengupta, 2010, Regulation of the mTor complex 1 by nutrients, growth factors, and stress, Mol. Cell, 40, 310, 10.1016/j.molcel.2010.09.026
Shi, 2008, MyD88 and Trif target Beclin 1 to trigger autophagy in macrophages, J. Biol. Chem., 283, 33175, 10.1074/jbc.M804478200
Shi, 2010, TRAF6 and A20 regulate lysine 63-linked ubiquitination of Beclin-1 to control TLR4-induced autophagy, Sci. Signal., 3, ra42, 10.1126/scisignal.2000751
Sumpter, 2010, Autophagy and innate immunity: triggering, targeting and tuning, Semin. Cell. Dev. Biol., 21, 699, 10.1016/j.semcdb.2010.04.003
Talloczy, 2002, Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway, Proc. Natl. Acad. Sci. USA, 99, 190, 10.1073/pnas.012485299
Talloczy, 2006, PKR-dependent autophagic degradation of herpes simplex virus type 1, Autophagy, 2, 24, 10.4161/auto.2176
Vicencio, 2009, The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1, Cell Death Differ., 16, 1006, 10.1038/cdd.2009.34
Webber, 2010, Coordinated regulation of autophagy by p38alpha MAPK through mAtg9 and p38IP, EMBO J., 29, 27, 10.1038/emboj.2009.321
Wei, 2008, JNK1-mediated phosphorylation of Bcl-2 regulates starvation-induced autophagy, Mol. Cell, 30, 678, 10.1016/j.molcel.2008.06.001
Weidberg, 2010, LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis, EMBO J., 29, 1792, 10.1038/emboj.2010.74
Williams, 2008, Novel targets for Huntington's disease in an mTOR-independent autophagy pathway, Nat. Chem. Biol., 4, 295, 10.1038/nchembio.79
Wirawan, 2010, Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria, Cell Death Disease, 1, e18, 10.1038/cddis.2009.16
Wong, 2010, Simultaneous induction of non-canonical autophagy and apoptosis in cancer cells by ROS-dependent ERK and JNK activation, PLoS ONE, 5, e9996, 10.1371/journal.pone.0009996
Xia, 2010, Control of basal autophagy by calpain1 mediated cleavage of ATG5, Autophagy, 6, 61, 10.4161/auto.6.1.10326
Yang, 2010, Mammalian autophagy: core molecular machinery and signaling regulation, Curr. Opin. Cell Biol., 22, 124, 10.1016/j.ceb.2009.11.014
Yang, 2010, Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance, Cell Metab., 11, 467, 10.1016/j.cmet.2010.04.005
Yla-Anttila, 2009, 3D tomography reveals connections between the phagophore and endoplasmic reticulum, Autophagy, 5, 1180, 10.4161/auto.5.8.10274
Yousefi, 2006, Calpain-mediated cleavage of Atg5 switches autophagy to apoptosis, Nat. Cell Biol., 8, 1124, 10.1038/ncb1482
Zalckvar, 2009, DAP-kinase-mediated phosphorylation on the BH3 domain of beclin 1 promotes dissociation of beclin 1 from Bcl-XL and induction of autophagy, EMBO Rep., 10, 285, 10.1038/embor.2008.246