Autoantibodies against citrullinated serum albumin in patients with rheumatoid arthritis

Journal of Translational Autoimmunity - Tập 2 - Trang 100023 - 2019
Amanda Hefton1, Shu Ying Liang1, Kathryn Ni1, Victoria Carter1, Kennedy Ukadike1, Christian Lood1, Tomas Mustelin1
1Division of Rheumatology, Department of Medicines, University of Washington, 750 Republican Street, Room E507, Seattle, WA 99108, United States

Tài liệu tham khảo

Schellekens, 1998, Citrulline is an essential constituent of antigenic determinants recognized by rheumatoid arthritis-specific autoantibodies, J. Clin. Investig., 101, 273, 10.1172/JCI1316 Yamada, 2005, Peptidylarginine deiminase type 4, anticitrullinated peptide antibodies, and rheumatoid arthritis, Autoimmun. Rev., 4, 201, 10.1016/j.autrev.2004.11.002 van Jaarsveld, 1999, The prognostic value of the antiperinuclear factor, anti-citrullinated peptide antibodies and rheumatoid factor in early rheumatoid arthritis, Clin. Exp. Rheumatol., 17, 689 Yamada, 2003, Peptidylarginine deiminase type 4: identification of a rheumatoid arthritis-susceptible gene, Trends Mol. Med., 9, 503, 10.1016/j.molmed.2003.09.010 Suzuki, 2003, Functional haplotypes of PADI4, encoding citrullinating enzyme peptidylarginine deiminase 4, are associated with rheumatoid arthritis, Nat. Genet., 34, 395, 10.1038/ng1206 Bicker, 2013, The protein arginine deiminases: structure, function, inhibition, and disease, Biopolymers, 99, 155, 10.1002/bip.22127 Hua, 2018, Peptidylarginine deiminase 4 -104C/T polymorphism and risk of rheumatoid arthritis: A pooled analysis based on different populations, PLoS One, 13, 10.1371/journal.pone.0193674 Too, 2012, Polymorphisms in peptidylarginine deiminase associate with rheumatoid arthritis in diverse Asian populations: evidence from MyEIRA study and meta-analysis, Arthritis Res. Ther., 14, R250, 10.1186/ar4093 Vossenaar, 2003, A growing family of citrullinating enzymes: genes, features and involvement in disease, Bioessays, 25, 1106, 10.1002/bies.10357 Jones, 2009, Protein arginine deiminase 4 (PAD4): Current understanding and future therapeutic potential, Curr. Opin. Drug Discov. Dev., 12, 616 Raijmakers, 2012, Elevated levels of fibrinogen-derived endogenous citrullinated peptides in synovial fluid of rheumatoid arthritis patients, Arthritis Res. Ther., 14, R114, 10.1186/ar3840 Khandpur, 2013, NETs are a source of citrullinated autoantigens and stimulate inflammatory responses in rheumatoid arthritis, Sci. Transl. Med., 5, 178ra40, 10.1126/scitranslmed.3005580 Nielen, 2005, Antibodies to citrullinated human fibrinogen (ACF) have diagnostic and prognostic value in early arthritis, Ann. Rheum. Dis., 64, 1199, 10.1136/ard.2004.029389 Hill, 2006, Serum autoantibodies that bind citrullinated fibrinogen are frequently found in patients with rheumatoid arthritis, J. Rheumatol., 33, 2115 Vossenaar, 2004, Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin, Arthritis Res. Ther., 6, R142, 10.1186/ar1149 Tutturen, 2014, Assessing the citrullinome in rheumatoid arthritis synovial fluid with and without enrichment of citrullinated peptides, J. Proteome Res., 13, 2867, 10.1021/pr500030x Zhou, 2018, Evidence for a direct link between PAD4-mediated citrullination and the oxidative burst in human neutrophils, Sci. Rep., 8, 15228, 10.1038/s41598-018-33385-z Wang, 2016, Identification of citrullinated peptides in the synovial fluid of patients with rheumatoid arthritis using LC-MALDI-TOF/TOF, Clin. Rheumatol., 35, 2185, 10.1007/s10067-016-3247-4 Romero, 2013, Immune-mediated pore-forming pathways induce cellular hypercitrullination and generate citrullinated autoantigens in rheumatoid arthritis, Sci. Transl. Med., 5, 10.1126/scitranslmed.3006869 Zhou, 2015, Characterization of the hypercitrullination reaction in human neutrophils and other Leukocytes, Mediat. Inflamm., 236451 van Beers, 2013, The rheumatoid arthritis synovial fluid citrullinome reveals novel citrullinated epitopes in apolipoprotein E, myeloid nuclear differentiation antigen, and beta-actin, Arthritis Rheum., 65, 69, 10.1002/art.37720 Spengler, 2015, Release of active peptidyl arginine deiminases by neutrophils can explain production of extracellular citrullinated autoantigens in rheumatoid arthritis synovial fluid, Arthritis Rheum., 67, 3135, 10.1002/art.39313 Zhou, 2017, Spontaneous secretion of the citrullination enzyme PAD2 and cell surface exposure of PAD4 by neutrophils, Front. Immunol., 8, 1200, 10.3389/fimmu.2017.01200 Bongartz, 2007, Citrullination in extra-articular manifestations of rheumatoid arthritis, Rheumatol., 46, 70, 10.1093/rheumatology/kel202 Arnab, 2013, Anti-CCP antibody in patients with established rheumatoid arthritis: does it predict adverse cardiovascular profile?, J. Cardiovasc. Dis. Res., 4, 102, 10.1016/j.jcdr.2012.09.003