Autisme, la piste génétique se confirme

Jamain, 2008, Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism, Proc. Natl Acad. Sci. USA, 105, 1710, 10.1073/pnas.0711555105 Tabuchi, 2007, A neuroligin-3 mutation implicated in autism increases inhibitory synaptic transmission in mice, Science, 318, 71, 10.1126/science.1146221 Jamain, 2003, Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism, Nat. Genet., 34, 27, 10.1038/ng1136 Durand, 2007, Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders, Nat. Genet., 39, 25, 10.1038/ng1933 Laummonnier, 2004, X-linked mental retardation and autism are associated with a mutation in the NLGN4 gene, a member of the neuroligin family, Am. J. Hum. Genet, 74, 552, 10.1086/382137 Szatmari, 2007, Mapping autism risk loci using genetic linkage and chromosomal rearrangements, Nat. Genet., 39, 319, 10.1038/ng1985 Melke, 2008, Abnormal Melatonin Synthesis in Autism Spectrum Disorders, Molecular Psychiatry, 13, 90, 10.1038/sj.mp.4002016 Wasdell, 2008, A randomized, placebo-controlled trial of controlled release melatonin treatment of delayed sleep phase syndrome and impaired sleep maintenance in children with neurodevelopmental disabilities, Journal of pineal research, 44, 57