Atypical macular hole formation after Anti-VEGF therapy for neovascular age-related macular degeneration: Coincidence or consequence?

Ferris, 1984, Age-related macular degeneration and blindness due to neovascular maculopathy, Arch Ophthalmol., 102, 1640, 10.1001/archopht.1984.01040031330019 Kabanarou, 2017, Full-thickness macular hole formation following anti-VEGF injections for neovascular age-related macular degeneration, Clin Interv Aging., 12, 911, 10.2147/CIA.S135364 Grigoropoulos, 2010, Full-thickness macular hole after intravitreal injection of ranibizumab in a patient with retinal pigment epithelium detachment and tear, Eur J Ophthalmol., 20, 469, 10.1177/112067211002000235 Moisseiev, 2010, Macular hole following intravitreal bevacizumab injection in choroidal neovascularization caused by age-related macular degeneration, Case Rep Ophthalmol., 1, 36, 10.1159/000319827 Okamoto, 2014, Intraoperative and fluorescein angiographic findings of a secondary macular hole associated with age-related macular degeneration treated by pars plana vitrectomy, BMC Ophthalmol., 14, 1, 10.1186/1471-2415-14-114 Duker, 2013, The International Vitreomacular Traction Study Group classification of vitreomacular adhesion, traction, and macular hole, Ophthalmology., 120, 2611, 10.1016/j.ophtha.2013.07.042 Jackson, 2013, Vitreous attachment in age-related macular degeneration, diabetic macular edema, and retinal vein occlusion: a systematic review and metaanalysis, Retina., 33, 1099, 10.1097/IAE.0b013e31828991d6 Querques, 2009, Macular hole following intravitreal ranibizumab injection for choroidal neovascular membrane caused by age-related macular degeneration, Acta Ophthalmol., 87, 235, 10.1111/j.1755-3768.2008.01226.x Zayit-Soudry, 2010, Safety evaluation of repeated intravitreal injections of bevacizumab and ranibizumab in rabbit eyes, Retina., 30, 671, 10.1097/IAE.0b013e3181c0858c Clemens, 2010, Macular hole formation in the presence of a pigment epithelial detachment after three consecutive intravitreal antivascular endothelial growth factor injections, J Ocul Pharmacol Therapeut., 26, 297, 10.1089/jop.2009.0140 Mojana, 2008, The role of abnormal vitreo¬macular adhesion in age-related macular degeneration: spectral optical coherence tomography and surgical results, Am J Ophthalmol., 146, 218, 10.1016/j.ajo.2008.04.027 Cazabon, 2010, Full- thickness macular hole formation associated with pigment epithelial detachment: link or coincidence?, Int Ophthalmol., 30, 739, 10.1007/s10792-010-9376-x Oshima, 2015, Full thickness macular hole case after intravitreal aflibercept treatment, BMC Ophthalmol., 15, 30, 10.1186/s12886-015-0021-3 Pauleikhoff, 2002, Pigment epithelial detachment in the elderly. Clinical differentiation, natural course and pathogenetic implications, Graefes Arch Clin Exp Ophthalmol., 240, 533, 10.1007/s00417-002-0505-8 Emerson, 2005, Spontaneous rip of the retinal pigment epithelium with a macular hole in neovascular agerelated macular degeneration, Am J Ophthalmol., 140, 316, 10.1016/j.ajo.2005.01.028 Cunningham, 2011, Incidence of retinal pigment epithelial tears after intravitreal ranibizumab injection for neovascular age-related macular degeneration, Ophthalmology., 118, 2447, 10.1016/j.ophtha.2011.05.026 Kumar, 2012, Lamellar macular hole after ranibizumab in a patient with neovascular age-related macular degeneration and vitreomacular adhesion, Retin Cases Brief Rep., 6, 109, 10.1097/ICB.0b013e31820a2f30 Rao, 2017, Prevalence and surgical outcomes of macular hole in eyes with age-related macular degeneration, Ophthalmol Retina., 1, 158, 10.1016/j.oret.2016.09.014 Miura, 2011, Macular hole formation after intravitreal bevacizumab administration in a patient with myopic choroidal neovascularization, Retin Cases Brief Rep., 5, 149, 10.1097/ICB.0b013e3181cd1da1 Theodossiadis, 2010, Vitrectomy for treatment of a lamellar hole in a patient with exudative macular degeneration: the role of vitreous traction elimination, Eur J Ophthalmol., 20, 1086, 10.1177/112067211002000613