Attenuation of neuromotor deficits by natural antioxidants of Decalepis hamiltonii in transgenic Drosophila model of Parkinson’s disease

Abbott, 2005, Excessive daytime sleepiness and subsequent development of Parkinson disease, Neurology, 65, 1442, 10.1212/01.wnl.0000183056.89590.0d

Aebi, 1984, Catalase in vitro, Methods Enzymol, 105, 121, 10.1016/S0076-6879(84)05016-3

Alam, 1997, A generalised increase in protein carbonyls in the brain in Parkinson’s but not incidental Lewy body disease, J Neurochem, 69, 1326, 10.1046/j.1471-4159.1997.69031326.x

Alam, 1997, Oxidative DNA damage in the parkinsonian brain: an apparent selective increase in 8-hydroxyguanine levels insubstantial nigra, J Neurochem, 69, 1196, 10.1046/j.1471-4159.1997.69031196.x

Bekris, 2010, The genetics of Parkinson disease, J Geriatr Psychiatry Neurol, 23, 228, 10.1177/0891988710383572

Betarbet, 2000, Chronic systemic pesticide exposure reproduces features of Parkinson’s disease, Nat Neurosci, 3, 1301, 10.1038/81834

Bieschke, 2010, EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity, PNAS, 107, 7710, 10.1073/pnas.0910723107

Black, 1974, Spectrofluorometric analysis of hydrogen peroxide, Anal Biochem, 58, 246, 10.1016/0003-2697(74)90464-3

Bonilla-Ramirez, 2013, Low doses of paraquat and polyphenols prolong life span and locomotor activity in knock down parkin Drosophila melanogaster exposed to oxidative stress stimuli: implication in autosomal recessive juvenile Parkinsonism, Gene, 512, 355, 10.1016/j.gene.2012.09.120

Bruguerolle, 2002, Biologic rhythms and Parkinson’s disease: a chronopharmacologic approach to considering fluctuations in function, Clin Neuropharmacol, 25, 194, 10.1097/00002826-200207000-00002

Casani, 2013, Antioxidant compound supplementation prevents oxidative damage in a Drosophila model of Parkinson’s disease, Free Radic Biol Med, 61C, 151, 10.1016/j.freeradbiomed.2013.03.021

Chartier-Harlin, 2004, Alpha-synuclein locus duplication as a cause of familial Parkinson’s disease, Lancet, 364, 1167, 10.1016/S0140-6736(04)17103-1

Chau, 2010, Rasagiline protects against alpha-synuclein induced sensitivity to oxidative stress in dopaminergic cells, Neurochem Int, 57, 525, 10.1016/j.neuint.2010.06.017

Chaudhuri, 2005, The non-motor symptom complex of Parkinson’s disease: a comprehensive assessment is essential, Curr Neurol Neurosci Rep, 5, 275, 10.1007/s11910-005-0072-6

Chaudhuri, 2007, Interaction of genetic and environmental factors in a Drosophila Parkinsonism model, J Neurosci, 27, 2457, 10.1523/JNEUROSCI.4239-06.2007

Conway, 2000, Acceleration of oligomerization, not fibrillization, is a shared property of both alpha-synuclein mutations linked to early-onset Parkinson’s disease: implications for pathogenesis and therapy, Proc Natl Acad Sci U S A, 97, 571, 10.1073/pnas.97.2.571

Cuervo, 2010, Protein degradation, aggregation, and misfolding, Mov Disord, 25, S49, 10.1002/mds.22718

De Rijk, 1999, Prevalence of Parkinson’s disease in Europe: a collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group, Neurology, 54, S21

Dexter, 1989, Basal lipid peroxidation in substantia nigra is increased in Parkinson’s disease, J Neurochem, 52, 381, 10.1111/j.1471-4159.1989.tb09133.x

Dexter, 1989, Increased nigral iron content and alterations in other metal ions occurring in brain in Parkinson’s disease, J Neurochem, 52, 1830, 10.1111/j.1471-4159.1989.tb07264.x

Farrer, 2004, Comparison of kindreds with Parkinsonism and alpha-synuclein genomic multiplications, Ann Neurol, 55, 174, 10.1002/ana.10846

Faust, 2009, Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson’s disease, BMC Neurosci, 10.1186/1471-2202-10-109

Feany, 2000, A Drosophila model of Parkinson’s disease, Nature, 404, 394, 10.1038/35006074

Ferreira, 2006, Sleep disruption, daytime somnolence and ‘sleep attacks’ in Parkinson’s disease: a clinical survey in PD patients and age-matched healthy volunteers, Eur J Neurol, 13, 209, 10.1111/j.1468-1331.2006.01262.x

Forno, 1996, Neuropathology of Parkinson’s disease, J Neuropathol Exp Neurol, 55, 259, 10.1097/00005072-199603000-00001

Good, 1992, Neuromelanin-containing neurons of the substantia nigra accumulate iron and aluminum in Parkinson’s disease: a LAMMA study, Brain Res, 593, 343, 10.1016/0006-8993(92)91334-B

Haddadi, 2013, Decalepis hamiltonii root extract attenuates the age-related decline in the cognitive function in Drosophila melanogaster, Behav Brain Res, 249, 8, 10.1016/j.bbr.2013.04.017

Haddadi, 2014, Brain aging, memory impairment and oxidative stress: a study in Drosophila melanogaster, Behav Brain Res, 259, 60, 10.1016/j.bbr.2013.10.036

Halliwell, 2006, Oxidative stress and neurodegeneration: where are we now?, J Neurochem, 97, 1634, 10.1111/j.1471-4159.2006.03907.x

Hirsch, 1992, Why are nigral catecholaminergic neurons more vulnerable than other cells in Parkinson’s disease?, Ann Neurol, 32, S88, 10.1002/ana.410320715

Jahromi, 2013, Neuroprotective effect of Decalepis hamiltonii in paraquat-induced neurotoxicity in Drosophila melanogaster: biochemical and behavioral evidences, Neurochem Res, 38, 2616, 10.1007/s11064-013-1179-9

Jankovic, 2008, Parkinson’s disease: clinical features and diagnosis, J Neurol Neurosurg Psychiatry, 79, 368, 10.1136/jnnp.2007.131045

Jenner, 1997, Oxidative mechanisms in nigral cell death in Parkinson’s disease, Mov Disord, 13, 24

Koh, 2006, A Drosophila model for age-associated changes in sleep:wake cycles, Proc Natl Acad Sci U S A, 103, 13843, 10.1073/pnas.0605903103

Koller, 2004, Neuroprotection in Parkinson’s disease: an elusive goal, Curr Neurol Neurosci Rep, 4, 277, 10.1007/s11910-004-0052-2

Kudo, 2011, Circadian dysfunction in a mouse model of Parkinson’s disease, Exp Neurol, 232, 66, 10.1016/j.expneurol.2011.08.003

Kudo, 2011, Dysfunctions in circadian behavior and physiology in mouse models of Huntington’s disease, Exp Neurol, 228, 80, 10.1016/j.expneurol.2010.12.011

Kum, 2011, Treatment of idiopathic Parkinson’s disease with traditional Chinese herbal medicine: a randomized placebo-controlled pilot clinical study, Evid Based Complement Alternat Med, 10.1093/ecam/nep116

Lavara-Culebras, 2007, Drosophila DJ-1 mutants are sensitive to oxidative stress and show reduced lifespan and motor deficits, Gene, 400, 158, 10.1016/j.gene.2007.06.013

Lavara-Culebras, 2010, Effects of pharmacological agents on the lifespan phenotype of Drosophila DJ-1beta mutants, Gene, 462, 26, 10.1016/j.gene.2010.04.009

Litvan, 2007, The etiopathogenesis of Parkinson disease and suggestions for future research. Part II, J Neuropathol Exp Neurol, 66, 329, 10.1097/nen.0b013e318053716a

Lowry, 1951, Protein measurement with the Folin phenol reagent, J Biol Chem, 193, 265, 10.1016/S0021-9258(19)52451-6

Lü, 2010, Molecular mechanisms and clinical applications of nordihydroguaiaretic acid (NDGA) and its derivatives: an update, Med Sci Monit, 16, RA93

Mancuso, 2007, Mitochondrial dysfunction, free radical generation and cellular stress response in neurodegenerative disorders, Front Biosci, 12, 107, 10.2741/2130

Marklund, 1974, Involvement of the superoxide anion radical in the autoxidation of pyrogallol and a convenient assay for superoxide dismutase, Eur J Biochem, 47, 469, 10.1111/j.1432-1033.1974.tb03714.x

McCormack, 2002, Environmental risk factors and Parkinson’s disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat, Neurobiol Dis, 10, 119, 10.1006/nbdi.2002.0507

Meulener, 2005, Drosophila DJ-1 mutants are selectively sensitive to environmental toxins associated with Parkinson’s disease, Curr Biol, 15, 1572, 10.1016/j.cub.2005.07.064

Mizuno, 2010, α-Synuclein transgenic Drosophila as a model of Parkinson’s disease and related synucleinopathies, Parkinsons Dis, 20, 212706

Muñoz-Soriano, 2011, Drosophila models of Parkinson’s disease: discovering relevant pathways and novel therapeutic strategies, Parkinsons Dis, 10.4061/2011/520640

Nayar, 1978, Pharmacognostical studies on the root of Decalepis hamiltonii Wt. and Arn., and comparison with Hemidesmus indicus (L.) R. Br., Proc Plant Sci, 87, 37, 10.1007/BF03046869

Nuytemans, 2010, Genetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation update, Hum Mutat, 31, 763, 10.1002/humu.21277

Ohkawa, 1979, Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction, Anal Biochem, 95, 351, 10.1016/0003-2697(79)90738-3

Olanow, 2007, The pathogenesis of cell death in Parkinson’s disease, Mov Disord, S335, 10.1002/mds.21675

Ono, 2006, Antioxidant compounds have potent anti-fibrillogenic and fibril-destabilizing effects for α-synuclein fibrils in vitro, J Neurochem, 97, 105, 10.1111/j.1471-4159.2006.03707.x

Pal, 2011, Nitrosative stress-induced Parkinsonian Lewy-like aggregates prevented through polyphenolic phytochemical analog intervention, Biochem Biophys Res Commun, 404, 324, 10.1016/j.bbrc.2010.11.117

Pallier, 2007, Pharmacological imposition of sleep slows cognitive decline and reverses dysregulation of circadian gene expression in a transgenic mouse model of Huntington’s disease, J Neurosci, 27, 7869, 10.1523/JNEUROSCI.0649-07.2007

Parkinson, 2002, An essay on the shaking palsy, J Neuropsychiatry Clin Neurosci, 14, 223, 10.1176/jnp.14.2.223

Pendleton, 2002, Effects of pharmacological agents upon a transgenic model of Parkinson’s disease in Drosophila melanogaster, J Pharmacol Exp Ther, 300, 91, 10.1124/jpet.300.1.91

Polymeropoulos, 1997, Mutation in the alpha-synuclein gene identified in families with Parkinson’s disease, Science, 276, 2045, 10.1126/science.276.5321.2045

Quilty, 2006, Alpha-synuclein is upregulated in neurones in response to chronic oxidative stress and is associated with neuroprotection, Exp Neurol, 199, 249, 10.1016/j.expneurol.2005.10.018

Refinetti, 2010

Rosato, 2006, Analysis of locomotor activity rhythms in Drosophila, Nat Protoc, 1, 559, 10.1038/nprot.2006.79

Rosbash, 1989, The molecular biology of circadian rhythms, Neuron, 3, 387, 10.1016/0896-6273(89)90199-2

Satake, 2009, Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson’s disease, Nat Genet, 41, 1303, 10.1038/ng.485

Sian-Hülsmann, 2011, The relevance of iron in the pathogenesis of Parkinson’s disease, J Neurochem, 118, 939, 10.1111/j.1471-4159.2010.07132.x

Siddique, 2013, GC–MS analysis of Eucalyptus citriodora leaf extract and its role on the dietary supplementation in transgenic Drosophila model of Parkinson’s disease, Food Chem Toxicol, 55, 29, 10.1016/j.fct.2012.12.028

Siddique YH, Khan W, Singh BR, Naqvi AH. (2013), Synthesis of alginate-curcumin nanocomposite and its protective role in transgenic Drosophila model of Parkinson’s disease. International Scholarly Research Notices.

Singleton, 2003, Alpha-synuclein locus triplication causes Parkinson’s disease, Science, 31, 841, 10.1126/science.1090278

Sofic, 1992, Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson’s disease, Neurosci Lett, 142, 128, 10.1016/0304-3940(92)90355-B

Srivastava, 2010, Neuroprotective effect of Decalepis hamiltonii roots against ethanol-induced oxidative stress, Food Chem, 119, 626, 10.1016/j.foodchem.2009.07.003

Srivastava, 2011, Antioxidant and cytoprotective properties of 2-(hydroxymethyl)-3-methoxybenzaldehyde, Food Chem, 128, 458, 10.1016/j.foodchem.2011.03.053

Srivastava, 2006, Antioxidant activity of the roots of Decalepis hamiltonii (Wight & Arn.), LWT-Food Sci Technol, 39, 1059, 10.1016/j.lwt.2005.07.005

Srivastava, 2006, Novel antioxidant compounds from the aqueous extract of the roots of Decalepis hamiltonii (Wight and Arn.) and their inhibitory effect on low-density lipoprotein oxidation, J Agric Food Chem, 54, 790, 10.1021/jf052433x

Srivastava, 2007, Isolation of ellagic acid from the aqueous extract of the roots of Decalepis hamiltonii: antioxidant activity and cytoprotective effect, Food Chem, 103, 224, 10.1016/j.foodchem.2006.08.010

Srivastava, 2009, Decalepis hamiltonii roots boost antioxidant status of rat liver and brain, J Sci Food Agric, 89, 2461, 10.1002/jsfa.3748

Stevens, 2004, Daytime sleepiness and alertness in patients with Parkinson disease, Sleep, 27, 967, 10.1093/sleep/27.5.967

Sulzer, 2007, Multiple hit hypotheses for dopamine neuron loss in Parkinson’s disease, Trends Neurosci, 30, 244, 10.1016/j.tins.2007.03.009

Tanimura, 1982, Genetic dimorphism in the taste sensitivity to trehalose in Drosophila melanogaster, J Comp Physiol, 147, 433, 10.1007/BF00612007

Thorpy, 2005, Parkinson’s disease and sleep, Neurol Clin, 23, 1187, 10.1016/j.ncl.2005.05.001

Uttara, 2009, Oxidative stress and neurodegenerative diseases: a review of upstream and downstream antioxidant therapeutic options, Curr Neuropharmacol, 7, 65, 10.2174/157015909787602823

Uversky, 2002, Biophysical properties of the synucleins and their propensities to fibrillate: inhibition of alpha-synuclein assembly by beta- and gamma-synucleins, J Biol Chem, 277, 11970, 10.1074/jbc.M109541200

Vauzour, 2008, The neuroprotective potential of flavonoids: a multiplicity of effects, Genes Nutr, 3, 115, 10.1007/s12263-008-0091-4

Vila, 2004, Genetic clues to the pathogenesis of Parkinson’s disease, Nat Med, 10 Suppl., S58, 10.1038/nm1068

Volles, 2003, Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in Parkinson’s disease, Biochemistry, 42, 7871, 10.1021/bi030086j

Vrailas-Mortimer, 2012, A survey of the protective effects of some commercially available antioxidant supplements in genetically and chemically induced models of oxidative stress in Drosophila melanogaster, Exp Gerontol, 47, 712, 10.1016/j.exger.2012.06.016

Wassef, 2007, Methionine sulfoxide reductase A and a dietary supplement S-methyl-l-cysteine prevent Parkinson’s-like symptoms, J Neurosci, 27, 12808, 10.1523/JNEUROSCI.0322-07.2007

Weber, 2006, Antioxidants, supplements, and Parkinson’s disease, Ann Pharmacother, 40, 935, 10.1345/aph.1G551

Xun, 2007, Lifetime proteomic profiling of an A30P alpha-synuclein Drosophila model of Parkinson’s disease, J Proteome Res, 6, 3729, 10.1021/pr0700504

Xun, 2007, Protein expression in a Drosophila model of Parkinson’s disease, J Proteome Res, 6, 348, 10.1021/pr060488o

Yacoubian, 2009, Targets for neuroprotection in Parkinson’s disease, Biochim Biophys Acta, 1792, 676, 10.1016/j.bbadis.2008.09.009

Yumino, 2002, Paraquat-and diquat-induced oxygen radical generation and lipid peroxidation in rat brain microsomes, J Biochem, 131, 565, 10.1093/oxfordjournals.jbchem.a003135

Zecca, 2001, Substantia nigra neuromelanin: structure, synthesis, and molecular behaviour, Mol Pathol, 54, 414