Attempts to infect small laboratory animals with the infective larvae of Onchocerca lienalis

Journal of Helminthology - Tập 55 Số 4 - Trang 247-249 - 1981
Simon Townson1, A. E. Bianco1, Dawn G. Owen1
1London School of Hygiene ami Tropical Medicine, Winches Farm Field Station, 395 Hat field Road, St. A Ibans, Hertfordshire, ALA OXQ. UK

Tóm tắt

All the natural hosts of Onchocerca parasites are large animals (MULLI-R, 1979) andthere is, therefore an urgent need to develop a small animal model for onchoccrciasis,preferably one that employs a strain of inbred host. Rodents have been usedsuccessfully as experimental hosts for the microfilariac of O. guiturosa (sec NELSON et al. 1966), O. cervicalis (see RAbalais, 1974), O. armilluta (see EL Bihari & Hussein, 1975) and O. ijibsoni (see Beveridge et al., 1980) but there have been few publishedattempts to infect these hosts with infective-stage larvae.

Từ khóa


Tài liệu tham khảo

Doenhoff, 1978, Studies On The Host Parasite Relationship in Schistosoma infected mice: the immunological dependence of parasite egg excretion., Immunology, 35, 771

10.1017/S0022149X00007380

Bianco, 1980, Large Scale Recovery Of Onchocerca Microfilariae from naturally infected cattle and horses., Transactions of the Royal Society of Tropical Medicine and Hygiene, 74, 109

10.2307/3279458

10.1017/S0022149X00022707

10.1016/0035-9203(66)90164-7

Muller, 1979, The Identification Of Onchocerca, 175

Duke, 1962, Experimental Transmission Of Onchocerca Volvulus From Man To A Chimpanzee., Transactions of the Royal Society of Tropical Medicine and Hygiene, 56, 271

Beveridge, 1980, Experimental Infection Of Laboratoryrodents And calves with microfilariae of Onchocerca gihsoni, Tropenmcdizin und Parasitologic, 3, 82