Atherosclerotic neovasculature MR imaging with mixed manganese–gadolinium nanocolloids in hyperlipidemic rabbits

Benson, 1926, Present status of coronary artery disease, Arch Pathol Lab Med, 2, 876 Constantinides, 1966, Plaque fissures in human coronary thrombosis, J Atheroscler Res, 6, 1, 10.1016/S0368-1319(66)80056-X Ambrose, 1985, Angiographic morphology and pathogenesis of unstable angina pectoris, J Am Coll Cardiol, 5, 609, 10.1016/S0735-1097(85)80384-3 Brown, 1986, Incomplete lysis of thrombus in the moderate underlying atherosclerotic lesion during intracoronary infusion of streptokinase for acute myocardial infarction: quantitative angiographic observations, Circulation, 73, 653, 10.1161/01.CIR.73.4.653 Moreno, 2004, Plaque neovascularization is increased in ruptured atherosclerotic lesions of human aorta: implications for plaque vulnerability, Circulation, 110, 2032, 10.1161/01.CIR.0000143233.87854.23 Moreno, 2006, Neovascularization in human atherosclerosis, Circulation, 113, 2245, 10.1161/CIRCULATIONAHA.105.578955 Sipkins, 1998, Detection of tumor angiogenesis in vivo by alphavbeta3-targeted magnetic resonance imaging, Nat Med, 4, 623, 10.1038/nm0598-623 Flacke, 2001, Novel MRI contrast agent for molecular imaging of fibrin: implications for detecting vulnerable plaques, Circulation, 104, 1280, 10.1161/hc3601.094303 Winter, 2003, Molecular imaging of angiogenesis in early-stage atherosclerosis with alpha(v)beta3-integrin-targeted nanoparticles, Circulation, 108, 2270, 10.1161/01.CIR.0000093185.16083.95 Schmieder, 2005, Molecular MR imaging of melanoma angiogenesis with alpha (v) beta (3)-targeted paramagnetic nanoparticles, Magn Reson Med, 53, 621, 10.1002/mrm.20391 Mulder, 2005, Mr molecular imaging and fluorescence microscopy for identification of activated tumor endothelium using a bimodal lipidic nanoparticle, FASEB J, 19, 2008, 10.1096/fj.05-4145fje Strijkers, 2005, Relaxivity of liposomal paramagnetic MRI contrast agents, MAGMA, 18, 186, 10.1007/s10334-005-0111-y Winter, 2006, Endothelial alpha(nu)beta(3)-integrin targeted fumagillin nanoparticles inhibit angiogenesis in atherosclerosis, Arterioscler Thromb Vasc Biol, 26, 2103, 10.1161/01.ATV.0000235724.11299.76 Schmieder, 2008, Three-dimensional MR mapping of angiogenesis with {alpha}5{beta}1({alpha}{nu}{beta}3)-targeted theranostic nanoparticles in the mda-mb-435 xenograft mouse model, FASEB J, 22, 4179, 10.1096/fj.08-112060 Winter, 2008, Antiangiogenic synergism of integrin-targeted fumagillin nanoparticles and atorvastatin in atherosclerosis, J Am Coll Cardiol Img, 1, 624, 10.1016/j.jcmg.2008.06.003 Sherry, 1988, Stability constants for Gd3+ binding to model DTPA-conjugates and DTPA-proteins: implications for their use as magnetic resonance contrast agents, Magn Reson Med, 8, 180, 10.1002/mrm.1910080208 Winter, 2005, Improved paramagnetic chelate for molecular imaging with MRI, J Magn Magn Mater, 293, 540, 10.1016/j.jmmm.2005.01.062 Pham, 2011, Variable antibody-dependent activation of complement by functionalized phospholipid nanoparticle surfaces, J Biol Chem, 286, 123, 10.1074/jbc.M110.180760 Pflugfelder, 1988, Acute myocardial ischemia: MR imaging with Mn-TP, Radiology, 167, 129, 10.1148/radiology.167.1.3347711 Pomeroy, 1989, Magnetic resonance imaging of acute myocardial ischemia using a manganese chelate, Mn-DPDP, Invest Radiol, 24, 531, 10.1097/00004424-198907000-00004 Saeed, 1989, Occlusive and reperfused myocardial infarcts: differentiation with Mn-DPDP-enhanced MR imaging, Radiology, 172, 59, 10.1148/radiology.172.1.2500678 Saeed, 2000, T1-relaxation kinetics of extracellular, intracellular and intravascular mr contrast agents in normal and acutely reperfused infarcted myocardium using echo-planar mr imaging, Eur Radiol, 10, 310, 10.1007/s003300050050 Troughton, 2004, Synthesis and evaluation of a high relaxivity manganese(II)-based MRI contrast agent, Inorg Chem, 43, 6313, 10.1021/ic049559g Pan, 2010, Revisiting an old friend: manganese-based MRI contrast agents, Wiley Interdiscip Rev Nanomed Nanobiotechnol Pan, 2009, Sensitive and efficient detection of thrombus with fibrin-specific manganese nanocolloids, Chem Commun (Camb), 22, 3234, 10.1039/b902875g Wang, 2015, Synergy between surface and core entrapped metals in a mixed manganese–gadolinium nanobeacon affords safer mr imaging of sparse biomarkers, Nanomedicine, 10.1016/j.nano.2014.12.009 Meoli, 2004, Noninvasive imaging of myocardial angiogenesis following experimental myocardial infarction, J Clin Invest, 113, 1684, 10.1172/JCI200420352 Pan, 2011, Molecular photoacoustic imaging of angiogenesis with integrin-targeted gold nanobeacons, FASEB J, 25, 875, 10.1096/fj.10-171728 Hockett, 2011, Simultaneous dual frequency 1H and 19F-open coil imaging of arthritic rabbit knee at 3T, IEEE Trans Med Imaging, 30, 22, 10.1109/TMI.2010.2056689 Brott, 2011, ASA/ACCF/AHA/AANN/AANS/ACR/ASNR/CNS/SAIP/SCAI/SIR/SNIS/SVM/SVS guideline on the management of patients with extracranial carotid and vertebral artery disease: executive summary, Stroke, 42, e420 Go, 2013, Heart disease and stroke statistics—2013 update: a report from the American Heart Association, Circulation, 127, e6, 10.1161/CIR.0b013e31828124ad Roger, 2012, Executive summary: heart disease and stroke statistics—2012 update: a report from the American Heart Association, Circulation, 125, 188, 10.1161/CIR.0b013e3182456d46 Roger, 2012, Heart disease and stroke statistics—2012 update: a report from the American Heart Association, Circulation, 125, e2, 10.1161/CIR.0b013e31823ac046 Grobner, 2006, Gadolinium—a specific trigger for the development of nephrogenic fibrosing dermopathy and nephrogenic systemic fibrosis?, Nephrol Dial Transplant, 21, 1104, 10.1093/ndt/gfk062 Ersoy, 2007, Biochemical safety profiles of gadolinium-based extracellular contrast agents and nephrogenic systemic fibrosis, J Magn Reson Imaging, 26, 1190, 10.1002/jmri.21135 Perkins, 2007, Warning regarding gadolinium and nephrogenic systemic fibrosis, Liver Transpl, 13, 1752 Mendonca-Dias, 1983, Paramagnetic contrast agents in nuclear magnetic resonance medical imaging, Semin Nucl Med, 13, 364, 10.1016/S0001-2998(83)80048-8 Calne, 1994, Manganism and idiopathic parkinsonism: similarities and differences, Neurology, 44, 1583, 10.1212/WNL.44.9.1583 Ye, 2012, Polydisulfide manganese(II) complexes as non-gadolinium biodegradable macromolecular MRI contrast agents, J Magn Reson Imaging, 35, 737, 10.1002/jmri.22848