Atherogenic indices in clinical practice and biomedical research: A short review

Hussein Abid1, Zainab Abid2
1Medical Laboratory Technology Department, Technical Institute of Baquba, Middle Technical University, Baqubah 32001, Iraq
2Health Directorate of Diyala, Ministry of Health, Baqubah 32001, Iraq

Tóm tắt

Cardiovascular diseases (CVD) represent a major cause of mortality and morbidity worldwide. To date, many physicians still requesting traditional lipid profile tests (TG, TC, HDL-C, and LDL-C) to confirm the clinical diagnosis related to CVD. However, using these tests may be inadequate for the prediction of CVD risk, especially in intermediate risk. For better clinical practice, laboratory diagnostic alternatives should constantly be evaluated and developed by physicians and laboratory scientists. In this review, we sought to focus on the benefits of lipid ratios (CRI-, CRI-II, AIP, AC, and CHOLindex) in supporting clinical diagnosis and how they can be calculated. To attain this aim, a literature search in reputed databases (PubMed and Scopus) was performed and peer-reviewed research articles were included to conduct this review. Short theoretical and practical notes about each index were accordingly included along with calculation formulas. Thus, the current article can assist new researchers and young physicians to review what supports their knowledge in managing early CVDs.    

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Tài liệu tham khảo

10.1186/s12887-017-0868-y

10.1038/clpt.2014.85

10.1093/eurheartj/ehs092

10.2147/VHRM.S92461

10.1016/j.ihj.2014.12.001

10.4103/2230-8210.91191

10.15420/ecr.2019.18

10.1016/j.pop.2012.11.003

10.4103/1596-3519.194280

10.1161/CIRCULATIONAHA.106.667428

10.1016/j.jacc.2005.02.088

10.1161/hc4201.097189

10.1194/jlr.P011668

10.1016/j.arcmed.2019.08.009

10.1097/MD.0000000000008058

10.1515/jpem-2016-0479

10.1016/j.endien.2017.10.014

10.1161/01.CIR.67.4.730

10.1016/j.jad.2014.09.038

10.1373/clinchem.2004.037556

10.5152/akd.2013.208

10.5152/akd.2013.098

10.1016/j.jacl.2010.02.005

10.1016/j.ijcha.2020.100545

10.1177/0003319720949804

10.1136/jim-2016-000248

10.1177/2048004017740478

10.4067/S0034-98872018001001112

10.1111/and.13906

Igharo, O. G. et al. Lipid profile and Atherogenic Indices in Nigerians Occupationally Exposed to e-waste: A Cardiovascular Risk Assessment Study. Maedica 15, 196–205 (2020) doi: https://dx.doi.org/10.26574/maedica.2020.15.2.196.

10.1186/s42358-019-0096-2

10.5152/eurasianjmed.2019.18350

10.5543/tkda.2018.93762

10.1016/j.numecd.2020.07.039

10.1080/13685538.2020.1749996

10.1111/j.1751-7141.2008.00011.x

10.1016/j.amjcard.2007.01.071

10.1016/S0002-9343(98)00212-5

Bhardwaj, S. et al. Atherogenic Index of Plasma, Castelli Risk Index and Atherogenic Coefficient-New Parameters in Assessing Cardiovascular Risk. International Journal of Pharmacy and Biological Sciences 3, 359–364 (2013).

10.1515/bjmg-2017-0002

10.14744/nci.2019.54936

10.2147/DMSO.S281894