Astrocyte tissue factor controls CNS hemostasis and autoimmune inflammation
Tài liệu tham khảo
Henrich-Noack, 2006, Focal ischemia induces expression of protease-activated receptor1 (PAR1) and PAR3 on microglia and enhances PAR4 labeling in the penumbra, Brain research, 1070, 232, 10.1016/j.brainres.2005.10.100
Park, 2010, Activation of microglial cells via protease-activated receptor 2 mediates neuronal cell death in cultured rat primary neuron, Nitric oxide: biology and chemistry/official journal of the Nitric Oxide Society, 22, 18, 10.1016/j.niox.2009.10.008
Striggow, 2001, Four different types of protease-activated receptors are widely expressed in the brain and are up-regulated in hippocampus by severe ischemia, The European journal of neuroscience, 14, 595, 10.1046/j.0953-816x.2001.01676.x
Wang, 2004, Expression of protease-activated receptors (PARs) in OLN-93 oligodendroglial cells and mechanism of PAR-1-induced calcium signaling, Neuroscience, 126, 69, 10.1016/j.neuroscience.2004.03.024
Drake, 1989, Selective cellular expression of tissue factor in human tissues. Implications for disorders of hemostasis and thrombosis, Am J Pathol, 134, 1087
Fleck, 1990, Localization of human tissue factor antigen by immunostaining with monospecific, polyclonal anti-human tissue factor antibody, Thromb Res, 59, 421, 10.1016/0049-3848(90)90148-6
Eddleston, 1993, Astrocytes are the primary source of tissue factor in the murine central nervous system. A role for astrocytes in cerebral hemostasis, J Clin Invest, 92, 349, 10.1172/JCI116573
Thomas, 1993, Tissue factor contributes to microvascular defects after focal cerebral ischemia, Stroke, 24, 847, 10.1161/01.STR.24.6.847
Nagai, 2010, Role of coagulation factors in cerebral venous sinus and cerebral microvascular thrombosis, Neurosurgery, 66, 560, 10.1227/01.NEU.0000365745.49583.FD
Gavins, 2011, Mechanisms of enhanced thrombus formation in cerebral microvessels of mice expressing hemoglobin-S, Blood, 117, 4125, 10.1182/blood-2010-08-301366
Wang, 2014, Abstract 76: Astrocyte Tissue Factor: Double-Edged Sword of Brain Hemostasis, Arteriosclerosis, Thrombosis, and Vascular Biology, 34, A76, 10.1161/atvb.34.suppl_1.76
Lo, 2003, Mechanisms, challenges and opportunities in stroke, Nat Rev Neurosci, 4, 399, 10.1038/nrn1106
van Asch, 2010, Incidence, case fatality, and functional outcome of intracerebral haemorrhage over time, according to age, sex, and ethnic origin: a systematic review and meta-analysis, The Lancet Neurology, 9, 167, 10.1016/S1474-4422(09)70340-0
Matsushita, 2000, Evidence for apoptosis after intercerebral hemorrhage in rat striatum, J Cereb Blood Flow Metab, 20, 396, 10.1097/00004647-200002000-00022
Davis, 2006, Hematoma growth is a determinant of mortality and poor outcome after intracerebral hemorrhage, Neurology, 66, 1175, 10.1212/01.wnl.0000208408.98482.99
Wagner, 2003, Heme and iron metabolism: role in cerebral hemorrhage, J Cereb Blood Flow Metab, 23, 629, 10.1097/01.WCB.0000073905.87928.6D
Gaasch, 2007, Brain iron toxicity: differential responses of astrocytes, neurons, and endothelial cells, Neurochem Res, 32, 1196, 10.1007/s11064-007-9290-4
Wang, 2014, Toll-like receptor 2/4 heterodimer mediates inflammatory injury in intracerebral hemorrhage, Ann Neurol, 75, 876, 10.1002/ana.24159
Egashira, 2015, Intercellular cross-talk in intracerebral hemorrhage, Brain research, 1623, 97, 10.1016/j.brainres.2015.04.003
Liu, 2010, Blood-brain barrier breakdown and repair by Src after thrombin-induced injury, Ann Neurol, 67, 526, 10.1002/ana.21924
Lekic, 2015, Protease-activated receptor 1 and 4 signal inhibition reduces preterm neonatal hemorrhagic brain injury, Stroke, 46, 1710, 10.1161/STROKEAHA.114.007889
Mayer, 2005, Recombinant activated factor VII for acute intracerebral hemorrhage, N Engl J Med, 352, 777, 10.1056/NEJMoa042991
Mayer, 2008, Efficacy and safety of recombinant activated factor VII for acute intracerebral hemorrhage, N Engl J Med, 358, 2127, 10.1056/NEJMoa0707534
Striggow, 2000, The protease thrombin is an endogenous mediator of hippocampal neuroprotection against ischemia at low concentrations but causes degeneration at high concentrations, Proc Natl Acad Sci U S A, 97, 2264, 10.1073/pnas.040552897
Granziera, 2007, Thrombin-induced ischemic tolerance is prevented by inhibiting c-jun N-terminal kinase, Brain research, 1148, 217, 10.1016/j.brainres.2007.02.025
Donovan, 1997, Thrombin induces apoptosis in cultured neurons and astrocytes via a pathway requiring tyrosine kinase and RhoA activities, J Neurosci, 17, 5316, 10.1523/JNEUROSCI.17-14-05316.1997
Chen, 2010, Thrombin mediates severe neurovascular injury during ischemia, Stroke, 41, 2348, 10.1161/STROKEAHA.110.584920
Choi, 2005, Thrombin-induced oxidative stress contributes to the death of hippocampal neurons in vivo: role of microglial NADPH oxidase, J Neurosci, 25, 4082, 10.1523/JNEUROSCI.4306-04.2005
Xue, 2001, Acute tissue damage after injections of thrombin and plasmin into rat striatum, Stroke, 32, 2164, 10.1161/hs0901.095408
Junge, 2003, The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia, Proc Natl Acad Sci U S A, 100, 13019, 10.1073/pnas.2235594100
Wang, 2012, Role of protease-activated receptor-1 in brain injury after experimental global cerebral ischemia, Stroke, 43, 2476, 10.1161/STROKEAHA.112.661819
Okada, 1994, Fibrin contributes to microvascular obstructions and parenchymal changes during early focal cerebral ischemia and reperfusion, Stroke, 25, 1847, 10.1161/01.STR.25.9.1847
Mao, 2010, Deficiency of PAR4 attenuates cerebral ischemia/reperfusion injury in mice, J Cereb Blood Flow Metab, 30, 1044, 10.1038/jcbfm.2009.283
Sandercock, 2015, Anticoagulants for acute ischaemic stroke, Cochrane Database Syst Rev, 3, 10.1002/14651858.CD000024.pub4
Hankey, 2012, Anticoagulant therapy for patients with ischaemic stroke, Nat Rev Neurol, 8, 319, 10.1038/nrneurol.2012.77
Granger, 2012, Newer oral anticoagulants should be used as first-line agents to prevent thromboembolism in patients with atrial fibrillation and risk factors for stroke or thromboembolism, Circulation, 125, 159, 10.1161/CIRCULATIONAHA.111.031146
Prabhakaran, 2015, Acute stroke intervention: a systematic review, JAMA, 313, 1451, 10.1001/jama.2015.3058
Cheng, 2003, Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective, Nature medicine, 9, 338, 10.1038/nm826
Liu, 2004, Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C, Nature medicine, 10, 1379, 10.1038/nm1122
Cheng, 2006, Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage, Nature medicine, 12, 1278, 10.1038/nm1498
Wang, 2012, An activated protein C analog with reduced anticoagulant activity extends the therapeutic window of tissue plasminogen activator for ischemic stroke in rodents, Stroke, 43, 2444, 10.1161/STROKEAHA.112.658997
Marik, 2007, Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity?, Brain, 130, 2800, 10.1093/brain/awm236
Adams, 2007, The fibrin-derived gamma 377–395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease, J Exp Med, 204, 571, 10.1084/jem.20061931
Davalos, 2012, Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation, Nature communications, 3, 1227, 10.1038/ncomms2230
Ryu, 2015, Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation, Nature communications, 6, 8164, 10.1038/ncomms9164
Han, 2008, Proteomic analysis of active multiple sclerosis lesions reveals therapeutic targets, Nature, 451, 1076, 10.1038/nature06559
Kim, 2015, Protease activated receptor-1 antagonist ameliorates the clinical symptoms of experimental autoimmune encephalomyelitis via inhibiting breakdown of blood-brain barrier, Journal of neurochemistry, 135, 577, 10.1111/jnc.13285
Griffin, 2015, Activated protein C: biased for translation, Blood, 125, 2898, 10.1182/blood-2015-02-355974
Noorbakhsh, 2006, Proteinase-activated receptor 2 modulates neuroinflammation in experimental autoimmune encephalomyelitis and multiple sclerosis, The Journal of experimental medicine, 203, 425, 10.1084/jem.20052148